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Bardelli

Achille Bardelli, Buguggiate IT

Achille Angelo Bardelli, Buguggiate IT

Patent application numberDescriptionPublished
20100298472COATING OF ORGANIC AND INORGANIC PIGMENTS WITH ACRYLIC RESINS - Coating of organic and inorganic pigments with acrylic resins, comprising a chemical compound consisting of particles of solid organic and inorganic substances, both defined as pigments, in that they are substances which absorb a fraction of the light and reflect the complementary part thereof, coated with acrylic and, optionally, aldehyde and/or ketone resins. The latter are deposited on the surface of the pigment by means of a process which envisages melting of the resin, consequent wetting and coating of the entire surface of the pigment with the resin in the melted state, the consequent cooling and subsequent step of grinding by means of mechanical systems operating in temperature conditions lower than 20° C., by means of cryogenic processes or granulate by means of a wet method with a water jet cutting action and separation of the granulates by the water on a vibrating screen and then dried on a spiral elevator. The product resulting from this invention will be used as a semifinished product for the colouring and pigmentation of powder paints and plastics as a monochromatic colouring material and or will also be used, after dissolving in a solvent, or in water with basic pH, as a pigmented paste or directly in solvent or water based resins in the liquid paints industry.11-25-2010

Alberto Bardelli, Torino IT

Patent application numberDescriptionPublished
20090075267K-ras and B-raf mutations and anti-EGFr antibody therapy - The present application relates to K-ras mutations, to polynucleotides encoding mutant K-ras polypeptides, and to methods of identifying K-ras mutations. The present application also relates to B-raf mutations, to polynucleotides encoding mutant B-raf polypeptides, to vectors containing those polynucleotides, and to methods of identifying B-raf mutations. The present application also relates to methods of diagnosing cancer; and methods and kits for predicting the usefulness of anti-EGFr specific binding agents in the treatment of tumors.03-19-2009
20090269344Anti-EGFR antibody therapy based on an increased copy number of the EGFR gene in tumor tissues - The invention relates to an indidualized and personalized diagnosis and therapy of cancer based on specific molecular alterations which occur in specific tumor tissue of specific tumor patient populations. The therapy and diagnostic is based on the findings that proliferation and tumor growth of specific EGFR bearing tumor tissue expressing an amplified EGFR gene copy number may be abolished by anti-EGFR antibodies, while other individual molecular alterations such as mutations occurring in tumor tissues are unaffected by the same anti-EGFR antibody treatment.10-29-2009
20110059434P13k pathway mutations in cancer - Given the important role of protein kinases in pathways affecting cellular growth and invasion, we have analyzed 340 serine/threonine kinases for genetic mutations in colorectal cancers. Mutations in eight genes were identified, including three members of the phosphatidylinositol-3-kinase (PI3K) pathway; the alterations in the latter genes each occurred in different tumors and did not overlap with mutations in PIK3CA or other non-serine-threonine kinase (STK) members of the PI3K pathway, suggesting that mutations in any of these genes had equivalent tumorigenic effects. These data demonstrate that the PI3K pathway is a major target for mutational activation in colorectal cancers and provide new opportunities for therapeutic intervention.03-10-2011

Patent applications by Alberto Bardelli, Torino IT

Alberto Bardelli, Baltimore, MD US

Patent application numberDescriptionPublished
20100184100Tyrosine Kinome - Protein kinases are important signaling molecules involved in tumorigenesis. Mutational analysis of the human tyrosine kinase gene family (98 genes) identified somatic alterations in −20% of colorectal cancers, with the majority of mutations occurring in NTRK3, FES, GUCY2F and a previously uncharacterized tyrosine kinase gene called MCCK/MLK4. Most alterations were in conserved residues affecting key regions of the kinase domain. These data represent a paradigm for the unbiased analysis of signal transducing genes in cancer and provide useful targets for therapeutic intervention.07-22-2010

Angelo Achille Bardelli, Buguggiate IT

Patent application numberDescriptionPublished
20100080923THERMOSETTING POWDER PAINTS - Thermosetting coloured powder paints to be used in electrostatic painting processes are described. These powder paints comprise not more than 30% by weight of at least one monochromatic pigment coated with at least one aldehyde and/or ketone resin, preferably 5 to 30% by weight, and up to 95% by weight of conversion agent, preferably 70 to 95% by weight; more than 90% of the particles of said at least one coated monochromatic pigment and said conversion agent have a particle size of between 10 and 40 microns, preferably between 15 and 35 microns. The coated monochromatic pigment and the conversion agent have the same specific weight which is between 1.3 and 1.7 g/cc.04-01-2010

Angelo Achille Bardelli, Buguggiate, VA US

Patent application numberDescriptionPublished
20080206568Coating of Organic and Inorganic Pigments with Aldehyde or Ketone Resins - Coating of organic and inorganic pigments with aldehyde or ketone resins, comprising a chemical compound consisting of particles of solid organic and inorganic substances, both defined as pigments, in that they are substances which absorb a fraction of the light and reflect the complementary part thereof, coated with aldehyde or ketone resins. The latter are deposited on the surface of the pigment by means of a process which envisages melting of the resin, consequent wetting and coating of the entire surface of the pigment with the resin in the melted state, the consequent cooling and subsequent step of atomization by means of mechanical systems operating in temperature conditions lower than 10° C., by means of cryogenic processes. The product resulting from this invention will be used as a semifinished product for the colouring and pigmentation of powder paints and plastics as a monochromatic colouring material and or will also be used, after dissolving in a solvent, as a pigmented paste in the liquid paints industry.08-28-2008

Anthony John Bardelli, Derby, CT US

Patent application numberDescriptionPublished
20110203600Cutting and storage device - Our invention is a combined cutting and storage device designed for use by a smoker who can not or chooses not to finish an entire cigarette. The device contains a cutting mechanism and a sealed storage compartment with a vertical pop-up lid for use with a single unfinished cigarette. A smoker can simply cut an unfinished cigarette or smoking material with the cutting means and place it in the sealed storage compartment for later use. The sealed storage compartment may be inserted into a box or pack of cigarettes.08-25-2011

Roberto Giorgio Bardelli, Fino Mornasco (como) IT

Patent application numberDescriptionPublished
20110156789CONTROL SYSTEM FOR A PHASE GENERATOR AND CORRESPONDING CONTROL METHOD - A control system for a phase generator including a delay block including delay units, and first and second multiplexers configured to receive output signals of each of the delay units and to respectively supply first and second output signals. The control system may include a controller configured to drive the first multiplexer and the second multiplexer respectively with a first select signal and a second select signal, a detection module configured to detect a phase difference between the first output signal and the second output signal and to generate a corresponding digital phase shift signal, the detection module including a phase comparator, and a Time-Digital converter circuit coupled thereto and having logic elements configured to generate the digital phase shift signal, and a logic circuit connected to the detection module and configured to process the digital phase shift signal and to generate a signal indicative of a control executed.06-30-2011