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Banfi

Aldo Banfi, Rodano IT

Patent application numberDescriptionPublished
20110230541PROCESS FOR THE PREPARATION OF ROTIGOTINE - A process for the preparation of Rotigotine (I) and of pharmaceutically acceptable salts thereof, which comprises the reductive amination of an amine of formula 6 with the 2-thienylacetic acid-sodium boron hydride complex and which makes use of hydrobromide 5 as an intermediate (II) The process is advantageous from the industrial point of view in that it allows to obtain Rotigotine with high enantiomeric purity starting from optically active 5,6,7,8-tetrahydro-6-(S)-N-propylamino-1-methoxy-naphthalene (2), avoiding the use of dangerous reactives, the need for difficult chromatographic separation or the formation of by-products. Furthermore, two novel crystalline forms are disclosed.09-22-2011

Aldo Banfi, Origgio IT

Patent application numberDescriptionPublished
20100226944PROCESS FOR THE PREPARATION OF CONTROLLED-RELEASE SOLID FORMULATIONS CONTAINING OXCARBAZEPINE, AND FORMULATIONS OBTAINABLE BY SAID PROCESS - The present invention relates to a process for the preparation of controlled-release solid oral pharmaceutical formulations of oxcarbazepine, and the pharmaceutical formulations obtainable by said process.09-09-2010

Andrea Banfi, Basel CH

Patent application numberDescriptionPublished
20100239535METHOD FOR ISOLATING HOMOGENEOUS POPULATIONS OF TRANSDUCED PROGENITORS STABLY EXPRESSING SPECIFIC LEVELS OF A TRANSGENE - The invention is directed to a method for producing precursor cells expressing a target gene, for example VEGF, at desired levels comprising stably transducing precursor cells with the target gene linked to a cell-surface marker gene, for example truncated CD8/CD809-23-2010

Angelo Banfi, Baden CH

Patent application numberDescriptionPublished
20110122877HIGH DEFINITION VIDEO/AUDIO DATA OVER IP NETWORKS - The system transmits High Definition (HD) video/audio data, e.g. a JPEG2000-compressed video stream multi-channel audio stream, over a packet switching network, e.g. an Ethernet or IP network. Both the transmitter unit VTB and the receiver unit VRB feature a modular structure consisting of a base module or baseboard common to both units and one or more exchangeable adapter cards attached to or inserted into the baseboards to perform selected functions. The basebord is unitary, i.e. identical for both the VTB and the VRB; its components are activated depending upon the baseboard being in a VTB or a VRB. Each card is unique and earmarked and serves a specific purpose, e.g. for video coding and decoding, SMPTE processing, clocking/re-clocking, audio embedding/extraction. Upon inserting a card into a baseboard, the earmark is identified and the baseboard configured as transmitter or receiver baseboard. Functions in the baseboard can be implemented in Field Programmable Gate Arrays (FPGAs) and the network management, configuration, and/or control of the transmitting and/or receiving processes be performed by a softcore processors. This inventive combination of modular hardware/software results in a cost-effective, reliable, and fast system for transmitting large data volumes over packet switching networks.05-26-2011

Biagio Banfi, Porro (como) IT

Botond Banfi, North Liberty, IA US

Patent application numberDescriptionPublished
20090246146HALIDES IN THE TREATMENT OF PATHOGENIC INFECTION - The present invention relates to the use of halides and halide salts for the treatment of microbial infections, including those caused by bacteria, fungi and viruses. The present invention takes advantage of endogenous immune function and augments this system using a non-toxic and inexpensive reagent that can be delivered to mucosal surfaces, for example, orally, topically, opthalmically and via inhalation.10-01-2009
20090263323Novel means and methods for the treatment of hearing loss and phantom hearing - This invention relates to a method of identifying a modulator of an NADPH oxidase, whereby said modulator is suitable as a lead compound and/or as a medicament for the treatment and/or prevention of hearing loss and/or phantom hearing, the method comprising the steps of (a) contacting a test compound with a protein, wherein said protein (i) comprises or consists of the amino acid sequence of any one of SEQ ID NO: 1, 3 or 5, or (ii) is encoded by a nucleic acid comprising or consisting of the sequence of any one of SEQ ID NO: 2, 4, 6, 23 or 24, or (iii) is a fragment of the protein according to (i) or (ii) and exhibits NADPH oxidase activity, or (iv) has a sequence at least 75% identical with the protein according to (i) or (ii) or with the fragment according to (iii) and exhibits NADPH oxidase activity, and optionally with one or more NADPH oxidase subunits, under conditions allowing binding of said test compound to said protein or, if present, said subunit(s); (b) optionally determining whether said test compound binds to said protein or, if present, said subunit(s); and (c) determining whether (ca) said test compound, upon contacting in step (a); or (cb) said test compound, upon binding in step (b) modulates the expression and/or activity of said protein or, if present, said subunit(s). Also provided are pharmaceutical compositions, medical uses and diagnostic uses of compounds of the invention.10-22-2009

Gaia Banfi, Lentate Sul Seveso (mi) IT

Patent application numberDescriptionPublished
20080200681Processes for preparing palonosetron salts - The present invention provides processes for preparing Palonosetron salts, especially, the hydrochloride salt and intermediates used to prepare Palonosetron salts.08-21-2008

Gaia Banfi, Lentate Sul Seveso IT

Patent application numberDescriptionPublished
20100016593CRYSTALLINE FORMS OF PALONOSETRON HYDROCHLORIDE - The present invention provides crystalline forms of Palonosetron hydrochloride, processes for their preparation and pharmaceutical compositions containing such crystalline forms of Palonosetron HCl.01-21-2010

Giuseppe Banfi, Gorla Maggiore (varese) IT

Patent application numberDescriptionPublished
20110312426ELASTIC COUPLING - An Elastic Coupling (12-22-2011

Leonardo Banfi, Novate Milanese IT

Patent application numberDescriptionPublished
20090209506AMINO DERIVATIVES OF BETA-HOMOANDROSTANES AND BETA-HETEROANDROSTANES - New aminoalkoxyimino derivatives at position 3 of substituted B-homoandrostanes and B-heteroandrostanes, processes for their preparation, and to pharmaceutical compositions containing them for the treatment of cardiovascular disorders, such as heart failure and hypertension. In particular compounds having the general formula (I) are described, where the radicals have the meanings described in detail in the application.08-20-2009
20110053902AMINO DERIVATIVES OF ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS - Compounds of formula (I) wherein: the groups are as defined in the description, are useful for the preparation of medicaments for the treatment of cardiovascular disorders, in particular heart failure and hypertension. The compounds are inhibitors of the enzymatic activity of the Na03-03-2011