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Baltzer

Axel W. Baltzer, Neuss DE

Patent application number	Description	Published
20110280935	VIRAL AND NON-VIRAL VECTORS AS VEHICLES FOR DELIVERING TRANSGENES FOR TREATING BONE PATHOLOGIES - The present invention relates to a method for treating bone pathologies comprising delivering a viral or non-viral delivery vehicle comprising genetic information (e.g. a transgene) encoding a therapeutic osteoinductive factor to target cells in vivo enabling the cells to produce the osteoinductive factor at the site of the bone pathology. The delivery is achieved by a simplified method which does not require cumbersome ex vivo techniques or additional matrix or scaffolding agents. Such viral and non-viral delivery vehicles of the present invention are derived from the following nonlimiting examples: adenoviruses, adeno-associated viruses, retroviruses, herpes simplex viruses, liposomes, and plasmids. The osteoinductive factors include, but are not limited to, growth factors, cytokines, growth factor inhibitors and cytokine inhibitors.	11-17-2011

Boris Baltzer, Nahe DE

Patent application number	Description	Published
20090150667	MOBILE SMARTCARD BASED AUTHENTICATION - In an authentication server, information representing a first part of a response to a challenge is received during the authentication preparation phase. The challenge and the first part of the response are stored for further use. The challenge is resent and information representing a second part of the response to the challenge is received during a modified authentication phase. The first and second parts of the response are checked against the challenge for authenticating the user. In a smartcard reader, the response received from the smartcard is sent to a computing device, when the smartcard reader received the challenge via an interface to the computing device during normal authentication. In response to the smartcard reader having received the challenge via the interface to the computing device during an authentication preparation phase, the smartcard reader sends the first part of the response to the computing device. In response to the smartcard reader having received the challenge via a user interface, it presents at least the second part of the response to a user via the user interface.	06-11-2009

Lars Baltzer, Uppsala SE

Patent application number	Description	Published
20090305298	Binder for C-Reactive Protein - A polypeptide dimer is provided wherein both protomers have a sequence according to SEQ ID NO: 1 and at least one phosphocholine derivative is attached to the polypeptide. The polypeptide shows a specific binding for C-reactive protein (CRP). The utilization of the polypeptide in assays for determining the concentration of CRP is described. The purification of CRP, and compositions comprising the CRP also are provided.	12-10-2009
20100304398	NOVEL DIAGNOSTIC SENSOR FOR RAPID AND REPRODUCIBLE RO52 PROTEIN DOMAIN DETECTION - The present invention relates to the use of specific synthetic sensor molecules for the discrimination of proteins and protein domains involved in autoimmunity. More specifically, in one embodiment, the invention relates to the detection of antibodies which bind to specific domains of the Ro52 protein. In another embodiment, the invention relates to the use of specific synthetic sensor molecules to identify domains of the Ro52 protein with different antibody specificities. The invention also includes a method for assessing the risk that a fetus will develop congenital heart block. The invention enables the evaluation and differential diagnosis of a range of autoimmune disorders, allowing appropriate treatment or more generally medical intervention decisions to be made.	12-02-2010
20110053833	SYNTHETIC PEPTIDES AND THEIR USE - At least one embodiment of the present invention relates to new peptides designed based on the sequence of human lactoferrin and to use thereof, in particular for treatment and/or prevention of infections, inflammations, tumours, pain, wounds and/or scars.	03-03-2011

Lars Baltzer, Goteborg SE

Patent application number	Description	Published
20080299180	Peptides based on the sequence of human lactoferrin and their use - The invention relates to new peptides formed of at least seven subsequent amino acids of the amino acids in position 12-40, counted from the N-terminal end, in the sequence constituting human lactoferrin, and preferably modifications thereof. The invention also relates to medicinal products comprising such peptides, especially intended for treatment and prevention of infections, inflammations and tumours. Furthermore, the invention relates to food stuff, e.g. infant formula food, comprising the above mentioned peptides.	12-04-2008
20090182119	CATALYTICALLY ACTIVE PEPTIDES - A catalytically active peptide comprising an imidazole function in position i flanked by at least one functional group to be amidated in position i+3+4k, where k is an integer equal to or higher than −1 or in position i−4−4n, wherein n is an integer equal to or higher than 0, characterized in that it also comprises at least one activating group in position i+4+4n or i−3−4n, respectively, wherein n is as above.	07-16-2009
20100099575	NOVEL POLYPEPTIDE SCAFFOLDS AND USE THEREOF - Novel peptide having a sequence according to SEQ. ID. No. 1, SEQ. ID. No. 2 and/or SEQ. ID. No. 3 are disclosed and also polypeptide scaffold consisting of a four helix bundle formed of two dimerized helix-loop-helix motifs, said helix-loop-helix motifs having sequences according to SEQ. ID. No. 1, SEQ. ID. No. 2 and/or SEQ. ID. No. 3 which may comprise a fluorescent probe at the side chain of Lys15 and a ligand with affinity for a target molecule at the side chain of Lys8 or Lys34.	04-22-2010