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Balsamo

Aldo Balsamo, Pisa IT

Patent application numberDescriptionPublished
20090239829THIOARYL SUBSTITUTED INHIBITORS OF ZINC PROTEASES AND THEIR USE - There are described compounds having the general formula (I) below and their pharmaceutically acceptable salts thereof, wherein E, X, m, q, R09-24-2009
20100087505Compounds Having Aryl-Sulphonamidic Structure Useful As Metalloproteases Inhibitors - The invention relates to aryl-sulphonamido compounds endowed with inhibitory activity against metallo proteases MMP, having formula (I) below04-08-2010

Aldo Balsamo, S. Concordio Lu IT

Patent application numberDescriptionPublished
200900934931-PHENYLALCOXY-2-BETA-PHENYLETHYL DERIVATIVES AS P-GLYCOPROTEIN (P-GP) INHIBITORS USEFUL IN DRUG RESISTANCE EVENTS - The invention relates to a new class of compounds, which are 1-phenylalcoxy-2-β-phenylethyl derivatives, as P-glycoprotein (P-GP) inhibitors. These compounds are useful in drug resistance events. They have been shown able to inhibit in a dose-dependent manner Glycoprotein-P (P-gp) activity in cell lines in which the expression of said glycoprotein is very high, like Caco-2 (human colon cancer) cells and MCF7/Adr (adriamycin-resistant human breast carcinoma) cells. The invention also relates to methods of production and the utilization of such compounds as medicaments useful in the treatment of states linked to the difficulty for some drugs to cross the blood-brain barrier (BBB) and generally within the context of the problems of drug resistance induced by chemotherapy agents.04-09-2009

Alessandro Balsamo, Torino IT

Patent application numberDescriptionPublished
20090024343METHOD OF DETERMINING GEOMETRIC ERRORS IN A MACHINE TOOL OR MEASURING MACHINE - A method of determining geometric errors in a machine tool or measuring machine having a mobile unit for moving a target within a measuring volume, the method including the steps of determining a first direction within the measuring volume; moving the target into a number of points along the direction by means of the mobile unit; measuring, by means of a measuring device, the abscissa of each of the points from an origin located along the first direction; acquiring the coordinates of each of the points by means of the machine; repeating the foregoing steps for a number of directions within the measuring volume; and determining error parameters of the machine on the basis of the abscissas measured by the measuring device, and the coordinates of the points acquired by the machine.01-22-2009

Anthony Balsamo, Lumberville, PA US

Patent application numberDescriptionPublished
20100331761Apparatus and Method for Dermatological Wound Healing - A method is provided for treating a dermatological wound. A first step of the method includes providing an iontophoretic apparatus. The iontophoretic apparatus includes at least one surface for contacting a surface of the dermatological wound, a current source electrically coupled to the apparatus, a suction mechanism operably coupled to the apparatus, and a source of therapeutic molecules. A second step of the method includes placing the at least one surface of the iontophoretic apparatus into contact with at least a portion of the dermatological wound surface. A third step of the method includes activating the current source so that a plurality of therapeutic molecules is delivered to the dermatological wound. A fourth step of the method includes activating the suction mechanism to remove fluid and/or debris from the dermatological wound. The second, third, and fourth steps of the method are repeated until the dermatological wound is sufficiently healed.12-30-2010

Arcangelo Di Balsamo US

Patent application numberDescriptionPublished
20090204854Method for monitoring data processing system availability - A method, system, and product for monitoring the availability of a data processing system are proposed. The system runs a management application involving the periodic transmission of blocks of data from multiple local computers to a central computer. Whenever a block of data must be transmitted by a generic local computer, an expected transmission delay of a next block of data (with respect to the current one) is estimated and attached to the block of data. The central computer receiving the updated block of data can calculate an expected receiving time of the next block of data accordingly. If the next block of data is not received in due time, the central computer determines a failure of the local computer. The central computer also scans a subset of ports of the local computer, to ascertain whether the problem is due to a temporary unavailability of the application.08-13-2009

Gaetano Balsamo, Pioltello IT

Patent application numberDescriptionPublished
20090192184Crystalline Polymorphs of Topotecan Hydrochloride and Methods for the Preparation Thereof - The invention relates to two novel crystalline form of Topotecan hydrochloride (Ia)07-30-2009

Gaetano Balsamo, Rodano IT

Patent application numberDescriptionPublished
20100179180CRYSTALLINE IRINOTECAN HYDROCHLORIDE AND METHODS FOR ITS PREPARATION - Disclosed is a crystalline form of irinotecan hydrochloride (I) and processes for the preparation thereof from crude irinotecan hydrochloride or another polymorphic form of irinotecan. Said crystalline form is particularly suitable for industrial use, because it is easily filtered and possesses characteristics of high stability and purity.07-15-2010

Joseph S. Balsamo, Lake Forest, IL US

Patent application numberDescriptionPublished
20100259043System and Method for Harnessing and Distributing Normally Wasted Human Energy - To harness the power generated by the fitness machines as a result of work expanded by human operators, the health equipment facility includes an On-Site Energy Generation, Storage and Distribution (GSD) module that serves as a medium between the local facility power distribution system and an external power grid. In general, the GSD module includes hardware, firmware and/or software for converting the mechanical energy generated by one or more fitness machines to electrical power, as well as computer executable instructions for allocating the electrical power between the local distribution system and an external power grid, or storing the generated power for future use.10-14-2010

Michael Balsamo, San Francisco, CA US

Patent application numberDescriptionPublished
20100253088ENERGY GENERATOR - Inertia driven energy harvesters including a movable arm, suspension system, gearing system, generator and energy distribution system. The energy harvesters enable the efficient capture and conversion of kinetic energy to electrical energy.10-07-2010

Michael Joseph Balsamo, San Francisco, CA US

Patent application numberDescriptionPublished
20110029156WIRELESS SENSOR SYSTEM FOR A MOTOR VEHICLE - A wireless sensor system for a transmission and other powertrain components in a motor vehicle includes a wireless sensor connected to a component of the motor vehicle. The wireless sensor includes an antenna in communication with a wireless power source and with a wireless transceiver. The wireless power source includes an emitter that creates an electromagnetic resonance between the emitter and the sensor. The wireless transceiver is in communication with the sensor and sends and receives signals to and from the wireless sensor.02-03-2011