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Balogh, Budapest
Adam Balogh, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20120000291 | FIXING DEVICE AND METHOD FOR FIXING IN AN OPENING IN A WALL - The invention relates to a fixing device ( | 01-05-2012 |
Attila Balogh, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20100026789 | Moveable console for holding an image acquisition or medical device, in particular for the purpose of brain surgical interventions, a method for 3d scanning, in particular, of parts of the human body, and for the electronic recording and reconstruction of information regarding the scanned object surface - A moveable console for holding an image acquisition or medical device, in particular for the purpose of brain surgical interventions. A method for the 3D scanning of, in particular, approached parts of the human body, and the electronic recording and reconstruction of information regarding the scanned object surface. | 02-04-2010 |
Gabor Balogh, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20080200668 | Industrial Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene-3-Oxo-17Alpha-Pregn-4-Ene-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process - The invention relates to an industrial process for the preparation of 17-hydroxy-6β,7β;15β,16β-bismethylene-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone of formula (I), and to the key-intermediates for this process. | 08-21-2008 |
| 20090312299 | Isolated Isomers of Norelgestromin and Methods of Making and Using the Same - The invention is directed to a process of preparing substantially pure d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-3E- and -3Z-oxime isomers, as well as a process for the synthesis of the mixture of isomers and the pure isomers. The invention also relates to substantially pure d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene20-yn-3-one-3E-oxime and substantially pure d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-3Z-oxime isomer. Further aspects of the invention include a composition comprising substantially pure d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene20-yn-3-one-3E-oxime or substantially pure d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-3Z-oxime isomer, and methods of treatment using said compositions. | 12-17-2009 |
| 20100137622 | INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11beta-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-- DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS - The present invention relates to a process for the synthesis of the known 17-acetoxy-11-β-[4-(dimethyl amino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione (further on CDB-4124) of formula (I) from 3,3-[1,2-ethandiyl-bis(oxy)]-oestr-5(10),9(11)-dien-17-one of formula (II). Compound CDB-4124 belongs to the group of anti-hormones. The process has the following steps: i) formation of an epoxide; ii) addition of hydrogen cyanide; iii) silylation of a hydroxyl group; iv) reaction with 4-(dimethylamino)-phenyl magnesium bromide Grignard reagent in the presence of CuCl (Teutsch reaction); v) silylation of a hydroxyl group with trimethyl chlorosilane; vi) reaction with diisobutyl aluminum hydride and after addition of acid to the reaction mixture; vii) methoxy-methylation with methoxy-methyl Grignard reagent formed in situ, while hydrolyzing the trimethylsilyl protective groups; viii) oxidation of a hydroxyl group with dicyclohexyl carbodiimide in the presence of dimethyl sulfoxide and a strong organic acid (Swern oxidation), and in given case after purification by chromatography; ix) acetylation of a hydroxyl group with acetic anhydride in the presence of perchloric acid, and in given case, purification by chromatography. The invention also relates to new intermediates of the process. | 06-03-2010 |
| 20100209967 | PROCESS FOR THE SYNTHESIS OF 9A-HYDROXY-STEROIDS - The present invention relates to a novel selective synthesis of 9α-hydroxy-steroid derivatives of the general formula (I) (I)—wherein the meaning of -A-A′- is —CH | 08-19-2010 |
Gábor Balogh, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20090312299 | Isolated Isomers of Norelgestromin and Methods of Making and Using the Same - The invention is directed to a process of preparing substantially pure d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-3E- and -3Z-oxime isomers, as well as a process for the synthesis of the mixture of isomers and the pure isomers. The invention also relates to substantially pure d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene20-yn-3-one-3E-oxime and substantially pure d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-3Z-oxime isomer. Further aspects of the invention include a composition comprising substantially pure d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene20-yn-3-one-3E-oxime or substantially pure d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-3Z-oxime isomer, and methods of treatment using said compositions. | 12-17-2009 |
| 20100137622 | INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11beta-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-- DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS - The present invention relates to a process for the synthesis of the known 17-acetoxy-11-β-[4-(dimethyl amino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione (further on CDB-4124) of formula (I) from 3,3-[1,2-ethandiyl-bis(oxy)]-oestr-5(10),9(11)-dien-17-one of formula (II). Compound CDB-4124 belongs to the group of anti-hormones. The process has the following steps: i) formation of an epoxide; ii) addition of hydrogen cyanide; iii) silylation of a hydroxyl group; iv) reaction with 4-(dimethylamino)-phenyl magnesium bromide Grignard reagent in the presence of CuCl (Teutsch reaction); v) silylation of a hydroxyl group with trimethyl chlorosilane; vi) reaction with diisobutyl aluminum hydride and after addition of acid to the reaction mixture; vii) methoxy-methylation with methoxy-methyl Grignard reagent formed in situ, while hydrolyzing the trimethylsilyl protective groups; viii) oxidation of a hydroxyl group with dicyclohexyl carbodiimide in the presence of dimethyl sulfoxide and a strong organic acid (Swern oxidation), and in given case after purification by chromatography; ix) acetylation of a hydroxyl group with acetic anhydride in the presence of perchloric acid, and in given case, purification by chromatography. The invention also relates to new intermediates of the process. | 06-03-2010 |
Levente Balogh, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20100189631 | PERMEATION METHOD AND APPARATUS FOR PREPARING FLUIDS CONTAINING HIGH PURITY CHLORINE DIOXIDE - Method to prepare fluids (liquids and gases) containing pure chlorine dioxide which is not contaminated by the starting materials or the byproducts of the chlorine dioxide synthesis or to deliver pure chlorine dioxide into any medium capable of dissolving chlorine dioxide, wherein the chlorine dioxide generated in the process is transported across a pore free polymeric membrane via selective permeation into the target medium. Apparatus to realize the said method, wherein the generation of chlorine dioxide is carried out in such a reactor where some or all walls comprising the reactor, or the walls of a permeator unit attached to the reactor, are made of the said pore free polymer, characteristically some kind of silicone rubber, which is highly permeable to chlorine dioxide, but which is practically impermeable for the acidic and corrosive reagents used for the chlorine dioxide synthesis, its permeability being at least 3 orders of magnitude lower for these contaminating components compared to that of chlorine dioxide. The invention can be realized both by batch and by continuous reactors. | 07-29-2010 |
Maria Balogh, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20080255110 | IMIDAZOQUINOLINE DERIVATIVES AS ADENOSINE A3 RECEPTOR LIGANDS - This invention is directed to a compound of formula (I), | 10-16-2008 |
Tibor Balogh, Budapest HU
| Patent application number | Description | Published |
|---|---|---|
| 20080204663 | Method And Apparatus For Generating 3D Images - The present invention is directed to an apparatus and method for displaying 3D images. The apparatus comprises: a) a screen with angular dependent diffusion characteristics for direction selectively forwarding light; b) a screen illuminating system, the screen illuminating system comprising multiple modules for generating multiple light beams incident on points of the screen, the modules being arranged so that each point of the screen is illuminated by multiple modules, and the incident light beams generated by one module are projected into multiple different directions from the module towards multiple different points of the screen, and further the different incident light beams generated by one module are forwarded towards different emitting directions from the screen, means for coding each incident light beam with the image information of a single image point in the module, where the 3D image perceived by an observer being generated by multiple modules; c) a control system to control the modules; and d) means for imparting an exit divergence to the exiting light beams being transmitted through or reflected from the screen, the measure of the exit divergence substantially corresponding to the angle between neighbouring emitting directions associated with the optically neighbouring modules, go as to provide a substantially continuous motion parallax in the 3D image perceived by an observer. The apparatus according to the invention comprises imaging means for generating the incident light beams with a convergent section converging substantially towards a point of the screen, where a convergence of the incident light beams is substantially equal to the exit divergence of the light beams exiting the screen. The modules can be video projectors, LED projectors, the optical engines of these, or the like, arranged periodically shifted, preferably in the horizontal direction and the diffuser screen is realised as a holographic screen, arrays of diffractive or refractive elements, retroreflective surfaces, or any combination thereof, for imparting a larger divergence to the exit light beams along at least one, preferably in the vertical direction, while in the other direction the angle of divergence provided by the screen is smaller than the angle between the neighbouring emitting directions associated with the optically neighbouring modules. The invention is also directed to a method implemented by the apparatus according to the invention. | 08-28-2008 |