Patent application number | Description | Published |
20100105605 | FATTY ACID FORMULATIONS AND ORAL DELIVERY OF PROTEINS AND PEPTIDES, AND USES THEREOF - Fatty acid compositions for administration of of pharmaceutical agents, such as proteins and peptides, protein and peptide conjugates, and/or cation-polypeptide conjugate complexes. In particular, the invention provides a solid pharmaceutical composition formulated for oral administration by ingestion, having from about 0.1 to about 75% w/w fatty acid component, where the fatty acid component comprises saturated or unsaturated C4, C5, C6, C7, C8, C9, C10, C11, or C12 fatty acids and/or salts of such fatty acids; and a therapeutic agent. Further, the invention provides a liquid pharmaceutical composition formulated for oral administration by ingestion, comprising: from about 0.1 to about 10% w/v fatty acid component, where the fatty acid component comprises saturated or unsaturated C4, C5, C6, C7, C8, C9, C10, C11, or C12 fatty acids and/or salts of such fatty acids; and a therapeutic agent. | 04-29-2010 |
20100105624 | CALCITONIN DRUG-OLIGOMER CONJUGATES, AND USES THEREOF - Calcitonin drug-oligomer conjugates that include a calcitonin drug coupled to an oligomer including a single polyalkylene glycol moiety consisting of between 4 and 10 polyalkylene glycol subunits are disclosed. Pharmaceutical compositions including such conjugates and methods of treating bone disorders by administering such conjugates are also disclosed. | 04-29-2010 |
20110118179 | CATION COMPLEXES OF INSULIN COMPOUND CONJUGATES, FORMULATIONS AND USES THEREOF - An insulin compound coupled to a modifying moiety having a formula: | 05-19-2011 |
20110124553 | INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF - An insulin compound coupled to a modifying moiety having a formula: | 05-26-2011 |
20140171357 | VANCOMYCIN DERIVATIVES - The invention features vancomycin class compounds modified to be suitable for oral delivery or to possess increased antimicrobial potency, formulations for the oral administration of vancomycin class compounds, and synthetic methods for making vancomycin class compounds. | 06-19-2014 |
20140329793 | PHARMACEUTICAL COMPOSITIONS AND USES THEREOF - The invention features pharmaceutical compositions including (i) a drug, and (ii) a PEG fatty acid ester or PPG fatty acid ester in an amount sufficient to increase the oral bioavailability of the drug. | 11-06-2014 |
20150024997 | ANTIFUNGAL AGENTS AND USES THEREOF - The invention features echinocandin class compounds. The compounds can be useful for the treatment of fungal infections. | 01-22-2015 |
20150087583 | DOSING REGIMENS FOR ECHINOCANDIN CLASS COMPOUNDS - The invention features pharmaceutical compositions, methods, and kits featuring dosing gimens and oral dosage formulations for administration of echinocandin class compounds. | 03-26-2015 |