| 20090076368 | Integrated imaging workstation and a method for improving, objectifying and documenting in vivo examinations of the uterus - Exemplary embodiments provide an imaging workstation with improved ergonomics, and a method for improving, objectifying and documenting in vivo examinations of the uterus. The imaging workstation may include an imaging head and a display, and may include mechanical supporting structures that allow the imaging head, display, and examination area to be simultaneously placed in an examiner's field of view. The imaging workstation may include means for the uniform application of a diagnostic marker. The method may involve acquiring a reference image of a tissue surface, applying a diagnostic marker and initiating image acquisition, acquiring tissue images in time sequence, aligning the captured images, and calculating dynamic optical curves and dynamic optical parameters from the images. The curves and parameters may be used to create a pseudocolor map representing different functional or structural features represented in the images, or different pathologies. | 03-19-2009 |
| 20090253991 | METHOD AND SYSTEM FOR CHARACTERIZATION AND MAPPING OF TISSUE LESIONS - The present invention provides a method and an apparatus for the in vivo, non-invasive, early detection of alterations and mapping of the grade of these alterations, causing in the biochemical and/or in the functional characteristics of the epithelial tissues during the development of tissue atypias, dysplasias, neoplasias and cancers. The method is based, at least in part, on the simultaneous measurement of the spatial, temporal and spectral alterations in the characteristics of the light that is re-emitted from the tissue under examination, as a result of a combined tissue excitation with light and special chemical agents. The topical or systematic administration of these agents result in an evanescent contrast enhancement between normal and abnormal areas of tissue. The apparatus enables the capturing of temporally successive imaging in one or more spectral bands simultaneously. Based on the measured data, the characteristic curves that express the agent-tissue interaction kinetics, as well as numerical parameters derived from these data, are determined in any spatial point of the examined area. Mapping and characterization of the lesion, are based on these parameters. | 10-08-2009 |
