| Patent application number | Description | Published |
|---|
| 20090004152 | METHODS OF PRODUCING PANCREATIC HORMONES - Disclosed herein are methods of producing pancreatic hormone-expressing cells by first differentiating pluripotent cells in cell culture so as to produce endodermal cells, the endodermal cells being competent to further differentiate into hormone-expressing cells capable of secreting at least one pancreatic hormone in response to a physiological signal, and then, transplanting the cultured endodermal cells into an organism, such as an organism in need of an endocrine cell therapy. | 01-01-2009 |
| 20090093372 | METHODS FOR INCREASING DEFINITIVE ENDODERM PRODUCTION - Disclosed herein are methods for increasing the production of definitive endoderm cells from pluripotent stem cells. Also disclosed herein are agents capable of increasing definitive endoderm cell production. | 04-09-2009 |
| 20090220959 | MARKERS OF DEFINITIVE ENDODERM - Disclosed herein are reagent-cell complexes comprising one or more definitive endoderm cells. Also described herein are compositions for detecting definitive endoderm. Method of enriching, isolating and/or purifying definitive endoderm cells are also disclosed. | 09-03-2009 |
| 20100197014 | METHODS FOR INCREASING DEFINITIVE ENDODERM PRODUCTION - Disclosed herein are methods for increasing the production of definitive endoderm cells from pluripotent stem cells. Also disclosed herein are agents capable of increasing definitive endoderm cell production. | 08-05-2010 |
| 20100260728 | METHODS OF PRODUCING PANCREATIC HORMONES - Disclosed herein are methods of producing pancreatic hormone-expressing cells by first differentiating pluripotent cells in cell culture so as to produce endodermal cells, the endodermal cells being competent to further differentiate into hormone-expressing cells capable of secreting at least one pancreatic hormone in response to a physiological signal, and then, transplanting the cultured endodermal cells into an organism, such as an organism in need of an endocrine cell therapy. | 10-14-2010 |
| 20100323442 | MODULATION OF THE PHOSPHATIDYLINOSITOL-3-KINASE PATHWAY IN THE DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS - Disclosed herein are cell cultures comprising differentiated human cells and methods of producing the same. The present invention provides compositions and methods for the production of differentiated human cells from human pluripotent cells. Preferably, the differentiated cells are selected from the group consisting of mesendoderm cells, definitive endoderm cells, ectoderm cells, trophectoderm cells, and extraembryonic endoderm cells. | 12-23-2010 |
| 20120009675 | METHODS OF PRODUCING PANCREATIC HORMONES - Disclosed herein are methods of producing pancreatic hormone-expressing cells by first differentiating pluripotent cells in cell culture so as to produce endodermal cells, the endodermal cells being competent to further differentiate into hormone-expressing cells capable of secreting at least one pancreatic hormone in response to a physiological signal, and then, transplanting the cultured endodermal cells into an organism, such as an organism in need of an endocrine cell therapy. | 01-12-2012 |
