| Patent application number | Description | Published |
| 20080278713 | Method for identifying refractive-index fluctuations of a target - Systems and methods for identifying refractive-index fluctuations of a target are described in this application. One embodiment includes identifying one or more properties of emergent light, the emergent light to be emergent from a target, and determining refractive-index fluctuations of the target based on the one or more properties of the emergent light. The determining refractive-index fluctuations further comprises determining one or more of the variance of the refractive-index fluctuations and the spatial correlation length of the refractive-index fluctuations. The determining refractive-index fluctuations further comprises determining one or more of the variance of the refractive-index fluctuations and the spatial correlation length of the refractive-index fluctuations. | 11-13-2008 |
| 20090009759 | Systems, methods and apparatuses of elastic light scattering spectroscopy and low coherence enhanced backscattering spectroscopy - Systems, methods, and apparatuses of elastic light scattering spectroscopy and low-coherence enhanced backscattering spectroscopy are described here. An apparatus couple-able to a light source and a target object, to facilitate light transmission between the light source and the target object, the apparatus comprises: a probe to emit incident light that is partially coherent obtained from the light source onto the target object and to receive interacted light, the interacted light to be backscattered light from illumination of the incident light on the target object, the probe comprising: a delivery channel having at least one delivery optical fiber with a distal end portion couple-able to the light source and a proximal end portion suited to couple the incident light to the target object, a collection channel having a first collection optical fiber suited to collect substantially co-polarized backscattered light and a second collection optical fiber suited to collect substantially cross-polarized backscattered light. | 01-08-2009 |
| 20090203977 | METHOD OF SCREENING FOR CANCER USING PARAMETERS OBTAINED BY THE DETECTION OF EARLY INCREASE IN MICROVASCULAR BLOOD CONTENT - The present invention, in one aspect, relates to screening test for tumors or lesions using what is referred to as “Early Increase in microvascular Blood Supply” (EIBS) that exists in tissues that are close to, but are not themselves, the abnormal tissue and in tissues that precede the development of such lesions or tumors. While the abnormal tissue can be a lesion or tumor, the abnormal tissue can also be tissue that precedes formation of a lesion or tumor, such as a precancerous adenoma, aberrant crypt foci, tissues that precede the development of dysplastic lesions that themselves do not yet exhibit dysplastic phenotype, and tissues in the vicinity of these lesions or pre-dysplastic tissues. | 08-13-2009 |
| 20100262020 | PROBE APPARATUS FOR RECOGNIZING ABNORMAL TISSUE - The present invention relates to probe apparatuses and component combinations thereof that are used to recognize possibly abnormal living tissue using a detected early increase in microvascular blood supply and corresponding applications. In one embodiment there is disclosed an apparatus that emits broadband light obtained from a light source onto microvasculature of tissue disposed within a human body and receives interacted light that is obtained from interaction of the broadband light with the microvasculature for transmission to a receiver. Different further embodiments include combinations of optical fibers, polarizers and lenses that assist in the selection of a predetermined depth profile of interacted light. In another embodiment, a kit apparatus is described that has various probe tips and/or light transmission elements that provide for various combinations of predetermined depth profiles of interacted light. In a further embodiment, a method of making a spectral data probe for depth range detection selectivity for detection of blood within microvasculature of tissue is described. | 10-14-2010 |