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Backer, US
Carl L. Backer, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20090299330 | Cellular Delivery Device - A cellular delivery device comprising a cellular carrier and an insertion device is provided. The cellular carrier includes at least one elongate strand of biocompatible material with a distal end and a proximal end. A stop member is connected to the proximal end of the elongate strand. The insertion device includes a needle attached to a hollow tubular body. The hollow tubular body is sized to receive the cellular carrier such that at least a portion of the elongate strand may be located within the hollow tubular body and the stop member protrudes from the proximal end of the hollow tubular body. | 12-03-2009 |
Gerald Peter Backer, Southfield, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110144788 | Method for simulating casting defects and microstructures of castings - Systems for predicting casting defects and microstructure in suppliers/vendors' castings for part/system durability analysis without knowing the details of the casting layout and casting gating and riser design as well as casting process parameters are provided. The systems involve the use of an integrated pore growth and interdendritic flow model. Methods of predicting casting defects and microstructures of a part without knowing the details of the casting layout and casting gating and riser design as well as casting process parameters and articles of manufacture are also provided. | 06-16-2011 |
Jerry Backer, Coon Rapids, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20090271708 | Collaboration Software With Real-Time Synchronization - A collaboration program operates on a computer system for storing, sharing and synchronizing data between different users. Centrally stored content data items are organized by associations into one or more folders, with the folders arranged by associations in a multi-level hierarchical structure. Users have access to all folders and content data items falling within at least one top level folder or “file cabinet” viewable by that user. When a user makes a change/addition to the hierarchical structure, that change/addition is transmitted to a server, which makes the change/addition to the necessary associations and sends messages through a TCP/IP format advising other signed-on users of the change/addition. With each content data item having the capability of being associated into multiple folders and each folder having the capability of being associated into multiple other folders or file cabinets, the computer system operating the collaboration program gives different users simultaneous, synchronized access to the folders and content data items in the hierarchical structure. | 10-29-2009 |
Joseph M. Backer, W. Simsbury, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080312410 | Cysteine-containing peptide tag for site-specific conjugation of proteins - The present invention is directed to a biological conjugate, comprising: (a) a targeting moiety comprising a polypeptide having an amino acid sequence comprising the polypeptide sequence of SEQ ID NO:2 and the polypeptide sequence of a selected targeting protein; and (b) a binding moiety bound to the targeting moiety; the biological conjugate having a covalent bond between the thiol group of SEQ ID NO:2 and a functional group in the binding moiety. The present invention is directed to a biological conjugate, comprising: (a) a targeting moiety comprising a polypeptide having an amino acid sequence comprising the polypeptide sequence of SEQ ID NO:2 and the polypeptide sequence of a selected targeting protein; and (b) a binding moiety that comprises an adapter protein, the adapter protein having a thiol group; the biological conjugate having a disulfide bond between the thiol group of SEQ ID NO:2 and the thiol group of the adapter protein. The present invention is also directed to biological sequences employed in the above biological conjugates, as well as pharmaceutical preparations and methods using the above biological conjugates. | 12-18-2008 |
| 20090023649 | Recombinant proteins containing shiga-like toxin and vascular endothelial growth factor fragments - The present invention is directed to an isolated polypeptide including: (1) the A subunit of Shiga-like bacterial toxin, wherein said subunit has the nucleic acid sequence of SEQ ID NO:9; and (2) human vascular endothelial growth factor wherein the growth factor has the nucleic acid sequence of SEQ ID NO:10; wherein the isolated polypeptide possesses ribosome inactivating activity. The present invention is also directed to compositions for inhibiting endothelial cell growth in a patient. | 01-22-2009 |
Joseph M. Backer, Sandy Hook, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100104550 | CLEAVAGE OF BIP BY SUBTILASE CYTOTOXIN - Cleavage of BIP (Immunoglobulin binding protein) by subtilase toxin and its application to inhibiting growth of or killing of cells. This has application to treatment of cancers and to conformational diseases and in particular to conformational diseases involving BiP that are influenced by cleavage by the subtilase cytotoxin. The invention also relates to subtilase toxin molecules specifically targeting proliferating cells, in particular tumor cells, or cells expressing a vascular endothelial growth factor receptor. | 04-29-2010 |
Joshua Backer, Atlanta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20090019060 | CREATING ONLINE SOCIAL LEARNING COMMUNITIES - Distributing knowledge through a learning community includes creating a plurality of learning communities; for each of the plurality of learning communities, allowing creating a knowledge base by the content producers, allowing submitting content to the learning community by the content consumers or the content producers; sharing contents with the content consumers and content producers in many ways. The learning communities are listed in a directory. A category in the directory is able to be drilled into for multiple levels. Each of the multiple levels of the categories in the directory is associated with one or more of the plurality of learning communities. | 01-15-2009 |
Marina V. Backer, Sandy Hook, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100104550 | CLEAVAGE OF BIP BY SUBTILASE CYTOTOXIN - Cleavage of BIP (Immunoglobulin binding protein) by subtilase toxin and its application to inhibiting growth of or killing of cells. This has application to treatment of cancers and to conformational diseases and in particular to conformational diseases involving BiP that are influenced by cleavage by the subtilase cytotoxin. The invention also relates to subtilase toxin molecules specifically targeting proliferating cells, in particular tumor cells, or cells expressing a vascular endothelial growth factor receptor. | 04-29-2010 |
Marina V. Backer, W. Simsbury, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080312410 | Cysteine-containing peptide tag for site-specific conjugation of proteins - The present invention is directed to a biological conjugate, comprising: (a) a targeting moiety comprising a polypeptide having an amino acid sequence comprising the polypeptide sequence of SEQ ID NO:2 and the polypeptide sequence of a selected targeting protein; and (b) a binding moiety bound to the targeting moiety; the biological conjugate having a covalent bond between the thiol group of SEQ ID NO:2 and a functional group in the binding moiety. The present invention is directed to a biological conjugate, comprising: (a) a targeting moiety comprising a polypeptide having an amino acid sequence comprising the polypeptide sequence of SEQ ID NO:2 and the polypeptide sequence of a selected targeting protein; and (b) a binding moiety that comprises an adapter protein, the adapter protein having a thiol group; the biological conjugate having a disulfide bond between the thiol group of SEQ ID NO:2 and the thiol group of the adapter protein. The present invention is also directed to biological sequences employed in the above biological conjugates, as well as pharmaceutical preparations and methods using the above biological conjugates. | 12-18-2008 |
| 20090023649 | Recombinant proteins containing shiga-like toxin and vascular endothelial growth factor fragments - The present invention is directed to an isolated polypeptide including: (1) the A subunit of Shiga-like bacterial toxin, wherein said subunit has the nucleic acid sequence of SEQ ID NO:9; and (2) human vascular endothelial growth factor wherein the growth factor has the nucleic acid sequence of SEQ ID NO:10; wherein the isolated polypeptide possesses ribosome inactivating activity. The present invention is also directed to compositions for inhibiting endothelial cell growth in a patient. | 01-22-2009 |
Ryan Thomas Backer, Minniapolis, MN US
Scott Andrew Backer, Philadelphia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100280281 | ALKOXYLATION OF FLUORINATED ALCOHOLS - A fluorinated alkylalkoxylate, and a process for its preparation in which at least one fluorinated alcohol is contacted with at least one alkylene epoxide in the presence of a catalyst system comprising an alkali metal borohydride, and an organic quaternary salt. | 11-04-2010 |