Patent application number | Description | Published |
20090271789 | METHOD, APPARATUS AND ARTICLE OF MANUFACTURE FOR TIMEOUT WAITS ON LOCKS - Embodiments of the invention provide techniques for performing timeout waits of process threads. Generally, a thread requesting access to locked resource sends a timeout request to a timeout handler process, and then goes to sleep. The timeout request is received by a receiving thread of the timeout handler process. The receiving thread may insert the timeout request into a minimum heap of timeout requests, and may determine whether the inserted request is due earlier than any of the existing timeout requests. If so, the receiving thread may interrupt a timing thread of the timeout handler process. The timing thread may then wait until reaching the requested timeout, and then send a wakeup message to the sleeping thread. | 10-29-2009 |
20140114864 | CASE MANAGEMENT INTEGRATION WITH EXTERNAL CONTENT REPOSITORIES - A case creation event originating from an external content repository is detected by a processor executing an inbound event handler of a distributed integration framework that integrates a case management system with the external content repository. The case creation event is configured by the distributed integration framework to cause creation of a case within the case management system. The inbound event handler instructs the case management system to create the case within the case management system. An outbound event handler of the distributed integration framework instructs the external content repository to create a proxy case to remotely represent the case created within the case management system. | 04-24-2014 |
20140114865 | CASE MANAGEMENT INTEGRATION WITH EXTERNAL CONTENT REPOSITORIES - A case creation event originating from an external content repository is detected by a processor executing an inbound event handler of a distributed integration framework that integrates a case management system with the external content repository. The case creation event is configured by the distributed integration framework to cause creation of a case within the case management system. The inbound event handler instructs the case management system to create the case within the case management system. An outbound event handler of the distributed integration framework instructs the external content repository to create a proxy case to remotely represent the case created within the case management system. | 04-24-2014 |
20140114918 | USE OF PROXY OBJECTS FOR INTEGRATION BETWEEN A CONTENT MANAGEMENT SYSTEM AND A CASE MANAGEMENT SYSTEM - Provided are techniques for synchronization. In response to an event that modifies a real object at a first content management system, another event is triggered to perform an action to modify a corresponding proxy object at a second content management system. In response to an event that modifies a real object at the second content management system, another event is triggered to perform an action to modify a corresponding proxy object at the first content management system. | 04-24-2014 |
Patent application number | Description | Published |
20090148382 | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof - One aspect of the invention relates to complexes of technetium (Tc) and rhenium (Re) with various heteroaromatic ligands, e.g., quinolinyl and isoquinolinyl ligands, and their use in fluorescence and radioimaging for a variety of clinical diagnostic applications, as well as radiopharmaceuticals for therapeutic applications. Another aspect of the invention relates to quinolinyl and isoquinolinyl ligands that form a portion of the aforementioned complexes. Methods for the preparation of the technetium and rhenium complexes are also described. Another aspect of the invention relates to quinolinyl and isoquinolinyl ligands based on derivatized lysine, alanine and bis-amino acids for conjugation to small peptides by solid phase synthetic methods. Additionally, the invention relates to methods for imaging regions of a mammal using the complexes of the invention. | 06-11-2009 |
20100303725 | Technetium- and Rhenium-Bis(heteroaryl) Complexes, and Methods of Use Thereof - One aspect of the invention relates to complexes of a radionuclide with various heteroaryl ligands, e.g., imidazolyl and pyridyl ligands, and their use in radiopharmaceuticals for a variety of clinical diagnostic and therapeutic applications. Another aspect of the invention relates to imidazolyl and pyridyl ligands that form a portion of the aforementioned complexes. Methods for the preparation of the radionuclide complexes are also described. Another aspect of the invention relates to imidazolyl and pyridyl ligands based on derivatized lysine, alanine and bis-amino acids for conjugation to small peptides by solid phase synthetic methods. Additionally, the invention relates to methods for imaging regions of a mammal using the complexes of the invention. | 12-02-2010 |
Patent application number | Description | Published |
20080312446 | IMAGING AGENTS FOR DIAGNOSIS OF PARKINSON'S DISEASE - Generally, the present invention is directed to central nervous system dopamine transporter-imaging agents and methods of use thereof. In certain embodiments, the present invention relates to radiolabeled piperidine derivatives for use as imaging agents in the diagnosis of Parkinson's disease. Another aspect of the present invention relates to piperidine monoamine transporter ligands, comprising a functional group capable of chelating a radionuclide, e.g., technetium, and methods of use thereof. | 12-18-2008 |
20090023787 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF - One aspect of the invention relates to novel complexes of technetium (Tc) with various heteroaromatic ligands, e.g., pyridyl and imidazolyl ligands, and their use in radiopharmaceuticals for a variety of clinical diagnostic and therapeutic applications. Another aspect of the invention relates to novel pyridyl ligands that form a portion of the aforementioned complexes. Methods for the preparation of the technetium complexes are also described. Another aspect of the invention relates to novel pyridyl ligands based on derivatized lysine, alanine and bis-amino acids for conjugation to small peptides by solid phase synthetic methods. Additionally, the invention relates to methods for imaging regions of a mammal using the complexes of the invention. | 01-22-2009 |
20090117032 | Imaging Agents for Early Detection and Monitoring of Cardiovascular Plaque - The present invention relates in part to imaging agents comprised of a targeting moiety and a label, such as a radionuclide or paramagnetic contrast agent, and methods of use thereof. | 05-07-2009 |
20100228012 | PENDANT FATTY ACID IMAGING AGENTS - The disclosure provides pendant fatty acid compounds for use in diagnostic imaging, (particularly the cardiovascular system), as well as kits comprised of the same. The disclosure also provides for a method administering a imaging agent with a high specificity for the myocardium. | 09-09-2010 |
20110206608 | Pharmaceutical Composition Of A Radioiodinated Benzamide Derivative And Methods Of Making Same - Provided is a pharmaceutical composition comprising radioiodinated N-(2-(diethylamino)ethyl)-4-(4-fluorobenzamido)-5-iodo-2-methoxybenzamide of Formula I. The pharmaceutical composition provides a stable formulation for both storing and administering to patients having melanoma. Also provided is a novel method of iodinating the precursor compound. | 08-25-2011 |
20110229410 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF - One aspect of the invention relates to novel complexes of technetium (Tc) with various heteroaromatic ligands, e.g., pyridyl and imidazolyl ligands, and their use in radiopharmaceuticals for a variety of clinical diagnostic and therapeutic applications. Another aspect of the invention relates to novel pyridyl ligands that form a portion of the aforementioned complexes. Methods for the preparation of the technetium complexes are also described. Another aspect of the invention relates to novel pyridyl ligands based on derivatized lysine, alanine and bis-amino acids for conjugation to small peptides by solid phase synthetic methods. Additionally, the invention relates to methods for imaging regions of a mammal using the complexes of the invention. | 09-22-2011 |