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| 20090004738 | Method and apparatus for maintenance and expansion of hemopoietic stem cells and/or progenitor cells - A method of preparing a stromal cell conditioned medium useful in expanding undifferentiated hemopoietic stem cells to increase the number of the hemopoietic stem cells is provided. The method comprising: (a) establishing a stromal cell culture in a stationary phase plug-flow bioreactor under continuous flow on a substrate in the form of a sheet, the substrate including a non-woven fibrous matrix forming a physiologically acceptable three-dimensional network of fibers, thereby expanding undifferentiated hemopoietic stem cells; and (b) when a desired stromal cell density has been achieved, collecting medium from the stationary phase plug-flow bioreactor, thereby obtaining the stromal cell conditioned medium useful in expanding the undifferentiated hemopoietic stem cells. | 01-01-2009 |
| 20120009673 | MESENCHYMAL STEM CELLS FOR THE TREATMENT OF CNS DISEASES - An isolated human cell is disclosed comprising at least one mesenchymal stem cell phenotype and secreting brain-derived neurotrophic factor (BDNF), wherein a basal secretion of the BDNF is at least five times greater than a basal secretion of the BDNF in a mesenchymal stem cell. Methods of generating same and uses of same are also disclosed. | 01-12-2012 |
| 20120122220 | METHOD AND APPARATUS FOR MAINTENANCE AND EXPANSION OF HEMOPOIETIC STEM CELLS AND/OR PROGENITOR CELLS - A method of preparing a stromal cell conditioned medium useful in expanding undifferentiated hemopoietic stem cells to increase the number of the hemopoietic stem cells is provided. The method comprising: (a) establishing a stromal cell culture in a stationary phase plug-flow bioreactor under continuous flow on a substrate in the form of a sheet, the substrate including a non-woven fibrous matrix forming a physiologically acceptable three-dimensional network of fibers, thereby expanding undifferentiated hemopoietic stem cells ; and (b) when a desired stromal cell density has been achieved, collecting medium from the stationary phase plug-flow bioreactor, thereby obtaining the stromal cell conditioned medium useful in expanding the undifferentiated hemopoietic stem cells. | 05-17-2012 |
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| 20080236473 | METHOD AND APPARATUS FOR CONTROLLING FRICTION BETWEEN A FLUID AND A BODY - A method and apparatus is disclosed wherein nanostructures or microstructures are disposed on a surface of a body (such as a submersible vehicle) that is adapted to move through a fluid, such as water. The nanostructures or microstructures are disposed on the surface in a way such that the contact between the surface and the fluid is reduced and, correspondingly, the friction between the surface and the fluid is reduced. In an illustrative embodiment, the surface is a surface on a submarine or other submersible vehicle (such as a torpedo). Illustratively, electrowetting principles are used to cause the fluid to at least partially penetrate the nanostructures or microstructures on the surface of the body in order to selectively create greater friction in a desired location of the surface. Such penetration may be used, for example, to create drag that alters the direction or speed of travel of the body. | 10-02-2008 |
| 20080280403 | TRANSISTOR FABRICATION METHOD - A method of forming low stack height transistors having controllable linewidth in an integrated circuit without channeling is disclosed. A disposable hardmask of doped glass is utilized to define the gate and subsequently protect the gate (and the underlying substrate) during ion implantation which forms the source and drains. A variety of silicided and non-silicided) structures may be formed. | 11-13-2008 |
| 20090008430 | Solder-bonding process - Methods include providing substrate having substrate surface, forming metal-containing pad on substrate surface, and forming metal-containing protective shell enclosing metal-containing body on metal-containing pad. Methods may include forming sacrificial layer on metal-containing pad and including top surface and cavity, cavity having side wall extending between metal-containing pad and top surface; and forming metal-containing protective shell in cavity. Methods may also include providing first, second, third and fourth metal-containing pads on first, second, third and fourth substrate surfaces; forming first metal-containing protective shell on first or second metal-containing pad; forming second metal-containing protective shell on third or fourth metal-containing pad; heating first metal-containing protective shell to form solder-bond between first and second substrate surfaces; and heating second metal-containing protective shell to form solder-bond between third and fourth substrate surfaces. | 01-08-2009 |
| 20090242036 | Directed-flow conduit - Device including channel having channel input and output. Channel has interior channel surface extending along channel path from channel input to output. In one implementation, channel includes plurality of channel sections in serial communication along channel path. Each of channel sections includes first internal circumference spaced apart along channel path from second internal circumference, in each of channel sections the first and second internal circumferences being substantially different. Each of channel sections includes sub-surface of interior channel surface. At least region of sub-surface of each channel section includes distribution of raised micro-scale features. As another implementation, at least first region of interior channel surface includes distribution of raised micro-scale features interrupted by plurality of raised barriers spaced apart along channel path on interior channel surface. Each raised barrier extends on interior channel surface in directions partially transverse to and partially parallel to longitudinal axis. Method also provided. | 10-01-2009 |
| 20090242175 | Thermal energy transfer device - Device having first wick evaporator including first membrane and plurality of first thermally-conductive supports. First membrane has upper and lower surfaces. First membrane also has plurality of pores with upper pore ends at upper surface of first membrane and with lower pore ends at lower surface of first membrane. Each of first thermally-conductive supports has upper and lower support ends. Upper support ends of first thermally-conductive supports are in contact with first membrane. Each of first thermally-conductive supports has longitudinal axis extending between the upper and lower support ends, average cross-sectional area along axis, and membrane support cross-sectional area at upper support end, the membrane support cross-sectional area effectively being smaller than average cross-sectional area. First thermally-conductive supports are configured to conduct thermal energy from lower support ends of first thermally-conductive supports to first membrane. Process includes providing wick evaporator, providing liquid working fluid in contact with lower or upper surface of membrane, and causing liquid working fluid to be evaporated from liquid-vapor interface in membrane. | 10-01-2009 |
| 20090274580 | METHOD AND APPARATUS FOR CONTROLLING THE MOVEMENT OF A LIQUID ON A NANOSTRUCTURED OR MICROSTRUCTURE SURFACE - A method and apparatus is disclosed wherein the movement of a droplet disposed on a nanostructured or microstructured surface is determined by at least one characteristic of the nanostructure feature pattern or at least one characteristic of the droplet. In one embodiment, the movement of the droplet is laterally determined by at least one characteristic of the nanostructure feature pattern such that the droplet moves in a desired direction along a nanostructured feature pattern. In another embodiment, the movement of the droplet is determined by either at least one characteristic of the nanostructure feature pattern or at least one characteristic of the droplet in a way such that the droplet penetrates the feature pattern at a desired area and becomes substantially immobile. | 11-05-2009 |
| 20100120216 | TRANSISTOR FABRICATION METHOD - A method of forming low stack height transistors having controllable linewidth in an integrated circuit without channeling is disclosed. A disposable hardmask of doped glass is utilized to define the gate and subsequently protect the gate (and the underlying substrate) during ion implantation which forms the source and drains. A variety of silicided and non-silicided) structures may be formed. | 05-13-2010 |
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| 20110066613 | Syndicated Data Stream Content Provisioning - Apparatus for syndicated data stream content provisioning, the apparatus comprising: an interaction tracker, configured to track at least one interaction of a user with at least one content object of a respective one of a group consisting of at least one syndicated data stream received on a computer device, the interaction being implicitly indicative of a preference of the user, a ranking function calculator, in communication with the interaction tracker, configured to calculate a ranking function based on the tracked interaction, and a content ranker, in communication with the ranking function calculator, configured to rank a plurality of content objects of the syndicated data streams of the group, in an order based on the calculated ranking function. | 03-17-2011 |
| 20110228708 | ETHERNET TRANSPORT OVER A TELEPHONE LINE - A modem for symmetric bi-directional transporting of an Ethernet signal, comprises a port connected to a physical layer module adapted to receive and transmit a single Ethernet signal, a data splitter for splitting the Ethernet signal into the configurable number of downstream data signals, another port comprising the configurable number of DSL ports coupled to the data splitter. Each port is adapted to transmit a separate downstream signal. Each transmitted downstream signal is transmitted via a corresponding telephone line connected to the port. Each port is further adapted to receive a separate upstream signal. Each received upstream signal is received over the corresponding telephone line connected to the DSL port, and a data collection and reorganization unit coupled to the DSL ports and adapted to assemble the upstream signals into the single Ethernet signal for transmission by the physical layer module. | 09-22-2011 |
