Aversa
Gregorio Aversa, Vancouver CA
Patent application number | Description | Published |
---|---|---|
20140287446 | Monoclonal Antibody For Acetylamantadine - A method of producing an antibody comprises immunizing a mammal with an amine-derivative of acetylamantadine, immunizing the mammal with acetylamantadine, and producing the antibody from the mammal. The antibody recognizes acetylamantadine but does not recognize amantadine. | 09-25-2014 |
Robert Aversa, Emeryville, CA US
Patent application number | Description | Published |
---|---|---|
20160038504 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS - The present invention provides compounds of Formula (I) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent. | 02-11-2016 |
Robert John Aversa, Cambridge, MA US
Patent application number | Description | Published |
---|---|---|
20160038504 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS - The present invention provides compounds of Formula (I) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent. | 02-11-2016 |
Samuel D. Aversa, Canandaigua, NY US
Patent application number | Description | Published |
---|---|---|
20140311101 | CHILD RESISTANT ZIPPER CLOSURE FOR RECLOSEABLE POUCH WITH DOUBLE SLIDER AND METHODS - A child resistant zipper closure for a plastic bag includes a double slider, including a first slider and second slider. The first and second sliders are oriented on the zipper closure such that when at least one of the first slider and second slider is moving in a direction toward the other of the first slider and second slider, the zipper is interlocking; and when at least one of the first slider and second slider is moving in a direction away from the other of the first slider and second slider, the zipper is unlocking. The first and second sliders can be releasably connected together. | 10-23-2014 |
Samuel D. Aversa, Canadaigua, NY US
Patent application number | Description | Published |
---|---|---|
20140311102 | CHILD RESISTANT ZIPPER CLOSURE FOR RECLOSEABLE POUCH WITH DOUBLE SLIDER AND METHODS - A child resistant zipper closure for a plastic bag includes a double slider, including a first slider and second slider. The first and second sliders are oriented on the zipper closure such that when at least one of the first slider and second slider is moving in a direction toward the other of the first slider and second slider, the zipper is interlocking; and when at least one of the first slider and second slider is moving in a direction away from the other of the first slider and second slider, the zipper is unlocking. The first and second sliders can be realeasably connected together. | 10-23-2014 |
Vincenzo Aversa, Ridgewood Swords IE
Patent application number | Description | Published |
---|---|---|
20130243873 | IMMUNOMODULATORY COMPOSITIONS - Immunomodulator formulations for use in the treatment of disease of the GI tract. The formulations comprise a hydroxylase inhibitor and/or an immunosuppressant. Exemplary formulations comprise hydralazine as a hydroxylase inhibitor and/or cyclosporin A as an immunosuppressant. | 09-19-2013 |
Vincenzo Aversa, Swords IE
Patent application number | Description | Published |
---|---|---|
20150342893 | CELECOXIB FORMULATIONS USEFUL FOR TREATING COLORECTAL CANCER - An oral celecoxib formulation, the formulation being a multiple minibead formulation wherein the minibeads comprise a hydrogel-forming polymer matrix in which are distributed celecoxib, a polyoxyethylated non-ionic surfactant and an anionic surfactant, the minibeads when combined with water being capable of releasing self-assembly structures comprising surfactant and celecoxib. | 12-03-2015 |
Vincenzo Aversa, Co. Dublin IE
Patent application number | Description | Published |
---|---|---|
20140017313 | FORMULATIONS - This invention relates to compositions for delivering one or more active ingredients, and more particularly to compositions, e.g. beads, comprising a matrix material which matrix material comprises a microorganism. In particular, the invention relates to compositions comprising a microorganism selected from live, killed, attenuated and inactivated microorganisms. The matrix material may also comprise a surfactant and may further comprise an adjuvant. The invention further relates to the manufacture and use of such compositions, and to other subject matter. | 01-16-2014 |
20140234418 | METHOD FOR TREATING INTESTINAL FIBROSIS - A method for treating intestinal fibrosis in a subject, comprising enterally administering a steroid to the subject. The steroid may be in a multiple minibead formulation. | 08-21-2014 |
Vincenzo Aversa, Dublin IE
Patent application number | Description | Published |
---|---|---|
20120141531 | COMPOSITION COMPRISING OIL DROPS - A composition comprises a water-soluble polymer matrix in which are dispersed droplets of oil, the composition comprising an active principle. The invention includes embodiments in which the active principle is included in at least some of the oil droplets as well as embodiments in which the oil droplets are free of active principle. The oil droplets are released as the matrix containing them dissolves in an aqueous medium. In one embodiment, the oil droplets are substantially immobilized in or by the matrix and the immobilizing feature is lost as the matrix dissolves in aqueous media. In certain embodiments, the oil drops may collectively be referred to as the oil phase of the composition of the invention. The product may be in the form of mini-beads. The oil phase and/or the polymer matrix may each include a surfactant. | 06-07-2012 |
20120141585 | IMMUNOMODULATORY COMPOSITIONS COMPRISING A POLYMER MATRIX AND AN OIL PHASE - A pharmaceutical composition comprising a water-soluble polymer matrix in which are dispersed droplets of oil, the composition comprising at least one immunomodulator selected from an adjuvant, an antigen or a combination thereof. A method of manufacturing shaped compositions comprises mixing an aqueous solution of a water-soluble polymer with an oil-based liquid to form a water-in-oil emulsion, at least one of the aqueous solution and the oil-based liquid comprising an antigen or an adjuvant or a combination thereof, and then causing or allowing the resultant suspension to solidify into one or more beads or other shaped elements | 06-07-2012 |
20150132374 | FORMULATIONS - A modified release composition comprising cyclosporin A for oral administration. The composition may comprise a core and a modified release coating, wherein the core comprises a hydrogel-forming polymer matrix and cyclosporin A. The composition may be in the form of a minibead. The compositions provide a pharmacokinetic profile and dissolution profile which provides release of cyclosporin A in the lower GI tract whilst minimising systemic exposure. Also disclosed are uses of the composition in the treatment of conditions affecting the lower GI tract, particularly the colon. | 05-14-2015 |
20150132396 | FORMULATIONS - The present invention relates to a formulation comprising a pharmaceutically active ingredient and a coating. The invention also relates to the use of the formulation in the treatment and prevention of disorders of the gastrointestinal tract. Also disclosed are methods for preparing the formulations. | 05-14-2015 |
20150182456 | HYDROGEL VACCINE FORMULATIONS - This invention relates to compositions for delivering one or more active ingredients, and more particularly to compositions, e.g. beads, comprising a matrix material which matrix material comprises a microorganism. In particular, the invention relates to compositions comprising a microorganism selected from live, killed, attenuated and inactivated microorganisms. The matrix material may also comprise a surfactant and may further comprise an adjuvant. The invention further relates to the manufacture and use of such compositions, and to other subject matter. | 07-02-2015 |