| Patent application number | Description | Published |
| 20100247517 | USE OF MNK INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE - The present invention relates to the use of modulators of the kinase activity of Mnk1 and/or Mnk2 the diagnosis, alleviation, treatment and/or prevention of a tauopathy. Particularly, the present invention relates to the use of a modulator of Mnk1 and/or Mnk2 kinase for the diagnosis, alleviation, treatment and/or prevention of Alzheimer's disease. Preferably, the compounds are condensed pyrimidines. | 09-30-2010 |
| 20110003741 | NOVEL NEURTURIN CONJUGATES FOR PHARMACEUTICAL USE - The present invention relates to neurturin protein products conjugated to polyols and to pharmaceutical compositions comprising neurturin conjugates as active ingredients, preferably PEGylated neurturin conjugates or variants thereof, having increased bioavailability. | 01-06-2011 |
| 20110212102 | HETEROCYCLOALKYL-CONTAINING THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS - The present invention relates to novel pharmaceutical compositions comprising thienopyrimidine compounds. Moreover, the present invention relates to the use of the thienopyrimidine compounds of the invention for the production of pharmaceutical compositions for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof. | 09-01-2011 |
| 20110212103 | THIENOPYRIMIDINES CONTAINING A SUBSTITUTED ALKYL GROUP FOR PHARMACEUTICAL COMPOSITIONS - The present invention relates to novel thienopyrimidine compounds of general formula | 09-01-2011 |
| 20110217311 | CYCLOALKYL CONTAINING THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS - The present invention relates to novel thienopyrimidine compounds of general formula | 09-08-2011 |
| 20110277045 | METHODS FOR INCREASING BETA CELL MASS COMPRISING ADMINISTERING A RA770 POLYPEPTIDE - The present invention discloses polynucleotides which identify and encode DP119, DP444, DP810, DP685, WE474, DP160, RA977, or RA770 as well as novel functions for these proteins of the inventions. The invention provides for compositions for disorders associated with the expression of the proteins of the invention, such as for the treatment, alleviation and/or prevention of pancreatic dysfunction (for example diabetes, hyperglycemia, and impaired glucose tolerance), and related disorders, and other disease and disorders. | 11-10-2011 |
| Patent application number | Description | Published |
| 20080207594 | Use of Gsk-3 Inhibitors for Preventing and Treating Pancreatic Autoimmune Disorders - This invention relates to the use of Pax4 stimulating compounds, e.g. Glycogen synthase kinase-3 (GSK-3) inhibitors, particularly in combination with immunomodulating agents, in the prevention, and/or treatment of pancreatic autoimmune disorders, e.g. type I diabetes or LADA. More particularly, this invention relates to the use of compounds selected from paullones, indirubines, substituted ureas, maleimide derivatives and pyrimidine thiones. Further, the present invention relates to a method of identifying and/or characterizing pancreatic beta-cell mitogens by using cells expressing a pancreatic gene or a gene whose function is controlled by a pancreatic gene, particularly the Pax4 gene, and which are transfected with a reporter gene. | 08-28-2008 |
| 20080241106 | Method for Preventing and Treating Diabetes Using Neurturin - The present invention relates generally to methods for preventing and/or treating pancreatic disorders, particularly those related to diabetes, by administering a neurturin protein product. | 10-02-2008 |
| 20090258829 | NEW FORMULATION FOR INCREASING BIOAVAILABILITY OF NEURTURIN - The present invention relates to formulations with protein growth factors, particularly neurturin as active ingredients and low molecular weight polyanionic excipients having increased bioavailability. | 10-15-2009 |
| 20110256113 | METHOD FOR PREVENTING AND TREATING DIABETES USING NEURTURIN - The present invention relates generally to methods for preventing and/or treating pancreatic disorders, particularly those related to diabetes, by administering a neurturin protein product. | 10-20-2011 |
| Patent application number | Description | Published |
| 20080256717 | Inflatable Two Chamber Bed with Raised Headboard - An inflatable mattress. The inflatable mattress comprises a support system having upper and lower inflatable support chambers arranged in a substantially vertical manner and an inflatable headboard chamber arranged in a substantially perpendicular manner to the upper and lower inflatable chambers. Each inflatable support chamber comprises a top layer and a bottom layer. The inflatable mattress may further comprise an inflatable reinforcing chamber disposed between the upper and lower inflatable support chambers and attached to the lower inflatable support chamber. | 10-23-2008 |
| 20080286117 | Pump with automatic deactivation mechanism - An automatic deactivation mechanism is configured for an air bladder pump having a casing and a motor located therein to pump air into an air bladder from the atmosphere and through an air valve connected through the casing. The automatic deactivation mechanism includes a housing positioned within the casing and has defined therethrough a first aperture in fluid communication with the atmosphere through the casing and a second aperture in fluid communication with the air bladder through the casing. Included within the housing are at least two switches and a diaphragm positioned between the switches. The housing is sealed so that when a threshold pressure is reached therein, at least one switch is triggered by deflection of the diaphragm to automatically deactivate the pump by de-energizing the motor. | 11-20-2008 |
| 20080286124 | PUMP FOR INFLATABLE OBJECTS WITH INTEGRATED LIGHT SOURCE - A pump for inflatable objects having a housing including an air inlet and an air outlet, a motor positioned within said housing, an impeller positioned within the housing for moving air, a light source defined on an exterior of the housing; and a reflector disposed on the housing proximate the light source. | 11-20-2008 |
| 20090085393 | Inflatable Chair With Cushion Top - Disclosed herein is an inflatable chair having at least three sections. The inflatable chair has a lower inflatable support chamber that has a top and bottom layer. The inflatable chair also has an upper cushioning portion and a stabilizing member. The upper cushioning portion and the stabilizing member are in fluid communication with the lower inflatable support chamber. The inflatable chair is made of a high elastic PVC material. | 04-02-2009 |
| 20110318194 | PUMP WITH AUTOMATIC DEACTIVATION MECHANISM - An automatic deactivation mechanism is configured for an air bladder pump having a casing and a motor located therein to pump air into an air bladder from the atmosphere and through an air valve connected through the casing. The automatic deactivation mechanism includes a housing positioned within the casing and has defined therethrough a first aperture in fluid communication with the atmosphere through the casing and a second aperture in fluid communication with the air bladder through the casing. Included within the housing are at least two switches and a diaphragm positioned between the switches. The housing is sealed so that when a threshold pressure is reached therein, at least one switch is triggered by deflection of the diaphragm to automatically deactivate the pump by de-energizing the motor. | 12-29-2011 |