Patent application number | Description | Published |
20090011003 | Composition for Suppressing Expression of Target Gene - The present invention has its object to provide a composition for suppressing the expression of a target gene and the like, and provides a composition, comprising an RNA-encapsulated liposome which comprises complex particles comprising as constituent components a lead particle and an RNA comprising a sequence consisting of 15 to 30 contiguous nucleotides of a target gene mRNA and a sequence complementary to the sequence, and a lipid membrane for coating the complex particles, wherein constituent components of the lipid membrane can be solved in a polar organic solvent, and wherein the polar organic solvent can be contained in a liquid at such a concentration that the constituent components of the lipid membrane are dispersible and the complex particles are dispersible, and the like. | 01-08-2009 |
20090041835 | METHOD OF INHIBITING LEAKAGE OF DRUG ENCAPSULATED IN LIPOSOMES - The present invention provides a method of inhibiting the leakage of a drug encapsulated in liposomes, which comprises satisfying at least two requirements selected from the group consisting of the following three requirements: using at least two lipid bilayers of the liposomes, controlling the average particle size of the liposomes to 120 nm or more, and using lipid having a phase transition temperature higher than in vivo temperature as lipid constituting the liposomes. Also, the present invention provides a liposome preparation which is stable in vivo and satisfies at least two requirements selected from the group consisting of the following three requirements: the number of lipid bilayers of the liposomes is at least two, the liposomes have an average particle size of 120 nm or more, and lipid constituting the liposomes has a phase transition temperature higher than in vivo temperature. | 02-12-2009 |
20130280248 | METHOD OF STABILIZING ANTIBODY AND STABILIZED SOLUTION-TYPE ANTIBODY PREPARATION - The present invention provides a method of suppressing the formation of a soluble association of an antibody in a solution; a method of suppressing the formation of a chemically degraded product of an antibody in a solution; and a method of stabilizing an antibody in a solution. The present invention also provides a solution-type antibody preparation in which the formation of a soluble association is suppressed; a solution-type antibody preparation in which the formation of a chemically degraded product is suppressed; a solution-type antibody preparation in which the formation of a soluble association, the formation of a chemically degraded product and the formation of an insoluble aggregate are suppressed; an agent for suppressing the formation of a soluble association of an antibody; an agent for suppressing the formation of a chemically degraded product of an antibody; and a stabilizing agent for an antibody. | 10-24-2013 |
20150190507 | METHOD OF STABILIZING ANTIBODY AND STABILIZED SOLUTION-TYPE ANTIBODY PREPARATION - The present invention provides a method of suppressing the formation of a soluble association of an antibody in a solution; a method of suppressing the formation of a chemically degraded product of an antibody in a solution; and a method of stabilizing an antibody in a solution. The present invention also provides a solution-type antibody preparation in which the formation of a soluble association is suppressed; a solution-type antibody preparation in which the formation of a chemically degraded product is suppressed; a solution-type antibody preparation in which the formation of a soluble association, the formation of a chemically degraded product and the formation of an insoluble aggregate are suppressed; an agent for suppressing the formation of a soluble association of an antibody; an agent for suppressing the formation of a chemically degraded product of an antibody; and a stabilizing agent for an antibody. | 07-09-2015 |
Patent application number | Description | Published |
20130218418 | VEHICLE STEERING SYSTEM - A vehicle steering system includes: a steering mechanism that includes a steering member, a steering angle detecting unit and a direction detecting unit that detects a steering direction with reference to a neutral position of the steering member; a steered mechanism that includes a steered wheel and a turning actuator having a turning motor, and that is not mechanically coupled to the steering mechanism; and a control device that controls the turning motor and that, at the time of a failure of the steering angle detecting unit, controls the turning motor by determining a turning motor command value for controlling the turning motor on the basis of a detected signal from the direction detecting unit. | 08-22-2013 |
20130220725 | VEHICLE STEERING SYSTEM - A vehicle steering system includes a rotation restriction mechanism that restricts a rotation amount of a steering member within a predetermined angle. The rotation restriction mechanism includes at least one plate element that is interposed between a rotatable element, which is coaxially rotatable together with a rotary shaft of the steering member, and a non-rotatable element, and that is rotatable relative to the rotary shaft. Light projecting units are provided at one of the rotatable element and the non-rotatable element, and light receiving units are provided at the other one of the rotatable element and the non-rotatable element. The at least one plate element has light transmission portions that allows transmission of light that is emitted from the light projecting units and that enters the light receiving units when a rotation angle of the at least one plate element is a predetermined angle. | 08-29-2013 |
20130245891 | VEHICLE STEERING CONTROL SYSTEM - The absolute value of a steering torque detected by a steering torque sensor is compared with a predetermined threshold. When the absolute value of the detected steering torque is smaller than the threshold, a steering reaction force is controlled on the basis of the steering torque; whereas, when the absolute value of the detected steering torque is larger than or equal to the threshold, the steering reaction force is controlled using a detected reaction motor current value as a reference value. | 09-19-2013 |
Patent application number | Description | Published |
20140184215 | EDDY CURRENT TESTING APPARATUS, EDDY CURRENT TESTING PROBE, AND EDDY CURRENT TESTING METHOD - An eddy current testing apparatus includes: an eddy current testing probe having an eddy current testing coil arranged on a bottom portion of a casing; a pressing mechanism configured to press the eddy current testing probe so that the bottom portion of the eddy current testing probe is placed in contact with a part of an inner wall surface of a slot formed in an object to be inspected; a carriage configured to mount the pressing mechanism and the eddy current testing probe, the carriage traveling in a depth direction of the slot; and an eddy current testing control device configured to control defect detection for the inner wall surface of the slot by acquiring a detected eddy current signal from the eddy current testing coil. | 07-03-2014 |
20140344434 | INFORMATION PROCESSING APPARATUS, INFORMATION PROCESSING METHOD, AND PROGRAM - There is provided an information processing apparatus including a receiver configured to receive an answer of a user to a question output from at least one device which has been uniquely identified on a network, and a device recognition part configured to recognize whether the user designates the device by comparing a correct answer to the question with the answer. | 11-20-2014 |
20140362258 | IMAGE PROCESSING APPARATUS, IMAGE PROCESSING METHOD, AND COMPUTER READABLE RECORDING MEDIUM - An image processing apparatus includes a special image processing unit. The special image processing unit includes an image resize unit that performs a resize process of resizing an image size of at least a partial area of an image area of image data by using one position in at least the partial area as a center, and an image composition unit that performs a composition process of compositing the image data and image data obtained through the resize process such that the respective one positions coincide with each other. | 12-11-2014 |
20150046170 | INFORMATION PROCESSING DEVICE, INFORMATION PROCESSING METHOD, AND PROGRAM - There is provided an information processing device including a processor configured to achieve a function of registering implicit preference information about a user on the basis of an activity of the user, a function of outputting a question to the user by voice on the basis of the implicit preference information, a function of acquiring an answer to the question from a voice spoken by the user, and a function of registering explicit preference information about the user depending on the answer. | 02-12-2015 |