Atsma
Bem Atsma, Abbotsford CA
Patent application number | Description | Published |
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20100105915 | CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS - Heterocyclic compounds that bind chemokine receptors and inhibit the binding of their natural ligands are disclosed. The invention compounds are protective against infection by HIV and exert effects characteristic of antagonists to the CXCR4 receptor. | 04-29-2010 |
Bem Atsma, Langley CA
Patent application number | Description | Published |
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20120301427 | CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY - The invention relates to heterocyclic compounds consisting of a core nitrogen atom surrounded by three pendant groups, wherein two of the three pendant groups are preferably benzimidazolyl methyl and tetrahydroquinolyl, and the third pendant group contains N and optionally contains additional rings. The compounds bind to chemokine receptors, including CXCR4 and CCR5, and demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HW). | 11-29-2012 |
20150038509 | Chemokine Receptor Binding Heterocyclic Compounds With Enhanced Efficacy - The invention relates to heterocyclic compounds consisting of a core nitrogen atom surrounded by three pendant groups, wherein two of the three pendant groups are preferably benzimidazolyl methyl and tetrahydroquinolyl, and the third pendant group contains N and optionally contains additional rings. The compounds bind to chemokine receptors, including CXCR4 and CCR5, and demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV). | 02-05-2015 |
Waatce Aize Atsma, Leeuwarden NL
Patent application number | Description | Published |
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20110207127 | MARKERS FOR DETECTION OF LEGIONELLA PNEUMOPHILA STRAINS - The invention relates to a method of detecting | 08-25-2011 |
Willem J. Atsma, Vancouver CA
Patent application number | Description | Published |
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20140148808 | TOOL WITH INTEGRATED NAVIGATION AND GUIDANCE SYSTEM AND RELATED APPARATUS AND METHODS - Methods and apparatus for integrating an electromagnetic navigation system and a tool and aligning the tool with a target are presented, including a sensor tool, a tool, a field generator, a display, and a computer. The sensor tool attaches to a target component in a unique position relative to target features. The field generator is fixed relative to the tool except in rotation about a tool axis. The display is adjustably mounted to the tool and automatically adjusts image parameters. Target registration and error compensation methods are provided. The system detects magnetic field and signal disturbances that may lead to inaccurate navigation, filters navigation data, and adjusts filtering parameters based on detected conditions. Apparatus for proximally locking an IM nail such that a clear passage through the cannulation of the nail is maintained are provided. | 05-29-2014 |