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| 20100105744 | SUBSTITUTED 7-SULFANYLMETHYL-, 7-SULFINYLMETHYL- AND 7-SULFONYLMETHYLINDOLES AND THE USE THEREOF - The present application relates to novel 7-sulfanylmethyl-, 7-sulfinylmethyl- and 7-sulfonylmethylindole derivatives, processes for the preparation thereof, the use thereof alone or in combinations for the treatment and/or prevention of diseases, and the use thereof for the manufacture of medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders. | 04-29-2010 |
| 20110183928 | 3-Cyanoalkyl- and 3-hydroxyalkylindoles and use thereof - The present application relates to novel 3-cyanoalkyl- and 3-hydroxyalkyl-substituted indole derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of cardiovascular diseases. | 07-28-2011 |
| 20110201564 | SUBSTITUTED 7-SULFANYLMETHYL, 7-SULFINYLMETHYL AND 7-SULFONYLMETHYL INDOLES AND USE THEREOF - The present application relates to novel 7-sulfanylmethyl-, 7-sulfinylmethyl- and 7-sulfonylmethylindole derivatives, processes for the preparation thereof, the use thereof alone or in combinations for the treatment and/or prevention of diseases, and the use thereof for the manufacture of medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders. | 08-18-2011 |
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| 20100028918 | GLUTAMINYL CYCLASE AS A DIAGNOSTIC/PROGNOSTIC INDICATOR FOR NEURODEGENERATIVE DISEASES - A method for predicting, diagnosing and prognosticating a neurodegenerative disease, such as Alzheimer's disease (AD), Mild Cognitive Impairment (MCI) and neurodegeneration in Down's syndrome (NDS) using glutaminyl cyclase (QC) as a diagnostic/prognostic indicator. The use of antibodies binding to QC and kits for performing said diagnostic method are also provided. | 02-04-2010 |
| 20100125086 | USE OF ISOQC INHIBITORS - The present invention relates in general to an inhibitor of a glutaminyl peptide cyclotransferase-like protein (QPCTL), and the use thereof for the treatment and/or prevention of an inflammatory disease or disorder selected from the group consisting of (a) chronic and acute inflammations, e.g. rheumatoid arthritis, atherosclerosis, restenosis, pancreatitis; (b) other inflammatory diseases, e.g. neuropathic pain, graft rejection/graft failure/graft vasculopathy, HIV infections/AIDS, gestosis, tuberous sclerosis, Guillain-Barré syndrome, chronic inflammatory demyelinising polyradiculoneuropathy and multiple sclerosis; (c) neuroinflammation; and (d) neurodegenerative diseases, e.g. mild cognitive impairment (MCI), Alzheimer's disease, neurodegeneration in Down Syndrome, Familial British Dementia, and Familial Danish Dementia, which may result from neuroinflammation. | 05-20-2010 |
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| 20090161819 | SYSTEMS AND METHODS FOR SCANNING AND DATA ACQUISITION IN COMPUTED TOMOGRAPHY (CT) APPLICATIONS - Systems and methods for data acquisition in computed tomography (CT) applications are provided. The systems and methods are particularly adapted for scanning and acquiring/processing data in connection with high-power cone-beam CT applications. The electron beam is moved/scanned along the anode surface to multiple focal positions. Data acquisition for a full projection at one focus position and one view angle is achieved by activating each focus position multiple times during the data acquisition for one angle of the gantry. The detector array and associated data processing system are adapted to rapidly switch between the different focus positions during the acquisitions for one view angle and to collect all data belonging to the same projection into the same data set. Adaptive electron optics are utilized to move/scan the electron beam along the anode surface to the various focus positions. Alternatively, a plurality of cathodes may be provided for respective focus positions and the system may support fast switching therebetween to achieve desirably short spot times. The disclosed CT system permits greater power densities without risk of heat damage to the anode and effectively increases the track velocity of the electron beam on the anode surface. The CT system and associated data acquisition methods have particular utility in CT applications requiring increased time resolution and/or spatial resolution, e.g., cardiac CT applications. | 06-25-2009 |
| 20090211884 | Electronic apparatus with a micro-electromechanical switch made of a piezoeletric material - The device improved according to the invention comprises a micro-electromechanical switch (MEMS) with a piezoelectric element connected to a mechanical support on both sides at the edges. The electrode design of this piezoelectric element is characterized by two electrodes mounted on at least one of the surfaces. | 08-27-2009 |
| 20100067662 | SWITCHING SCHEME FOR A STEREO ROTATING ANODE TUBE - For x-ray tubes the focal spot temperature is a critical factor. According to an exemplary embodiment of the present invention, an examination apparatus is provided which has a synchronisation unit providing an operation mode for a stereo tube in which the anode rotation frequency is synchronised with the switching frequency such that the switching frequency is a half integer multiple of the anode rotation frequency. This may lead to a significant reduction of the focal spot temperature. | 03-18-2010 |
| 20100239063 | ROTATING ANODE X-RAY TUBE WIBH A SADDLE SHAPED ANODE - The rotating anode x-ray tube comprises an anode, whose focal track has the shape of a saddle trajectory. A proper anode angle to enable a high power line focus is always realised along the focal path on the anode. The x-ray tube is for CT scanners and enables a movement of the focal spot along the patient axis during gantry rotation. In this way, cone beam artefacts due to the reconstruction may be avoided. | 09-23-2010 |
| 20110051895 | X-RAY SYSTEM WITH EFFICIENT ANODE HEAT DISSIPATION - X-ray systems for use in high-resolution imaging applications with an improved power rating are provided. An X-ray source comprises at least one integrated actuator unit ( | 03-03-2011 |
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| 20090010820 | Micro-Fluidic System - In one aspect, a micro-fluidic system consisting of modules that are arranged side by side in a row, each module containing a micro-fluidic unit and an associated electric control unit is provided. The rear faces of the modules lie against a common vertical rear wall unit and are held against the unit. In the modules, the respective control unit is located in the vicinity of the rear face and the micro-fluidic unit is situated in a region that is remote from the rear face. The control units can be connected to an electric line bus that runs through the rear wall unit via electric connectors that are located on the rear faces of the modules and on the rear wall unit and the micro-fluidic units of two respective neighboring modules are interconnected to allow the passage of fluid via a connecting part that contains connection channels and that spans the relevant modules. | 01-08-2009 |
| 20090126504 | Microfluidic System - The microfluidic system is constituted of modules that comprise one microfluidic unit and one corresponding electric control unit each and that are retained on a rear panel unit next to each other in a row. To prevent the formation of accumulation of ignitable or toxic gas mixtures a fluid conduit for a rinsing fluid extends through the rear panel unit. Branches lead from said fluid conduit to the modules, and said branches flowing into respective distributor compartments that extend vertically across the module height in the modules. Said distributor compartments are delimited in relation to the interior of the respective module by a distributor panel that is provide with openings. The interior of the respective module comprises, on its lower or rear surface, an exit opening for the rinsing fluid. | 05-21-2009 |
| 20100008834 | MICROFLUIDIC SYSTEM - There is described a microfluid system with a microchannel structure for the passage of fluids and a further channel structure separated from the microstructure by means of at least one separating wall for the passage of a heat transfer fluid. The risk of internal leakage in the microfluid system can be recognized in time, by separation of the microchannel structure from a cavity of at least one point by a further separating wall, said separating wall being at least locally weaker than the separating wall between the microchannel structure and the further channel structure and said cavity is connected to a detector device for detection of ingressing fluid. | 01-14-2010 |
| 20100021345 | Modular Microfluidic System - There is described a modular microfluidic system with the following features: Modules are arranged next to each other in a row. Every module has a microfluidic part which rests on a contact surface of the module in a locally limited area and is forced against the same by means of a fastening element. The microfluidic part comprises a fluid channel system with fluid connections that are arranged on the top surface of the microfluidic part in edge areas relative to the adjoining microfluidic parts. The fluid connections of adjoining microfluidic parts are interlinked by respective connecting channels in a connecting part bridging the microfluidic parts, said connecting part resting on the microfluidic parts in the edge areas. A clamping part rests against the lower surfaces of the adjoining microfluidic parts and is connected to the connecting part via an additional fastening element in the area between the microfluidic parts. | 01-28-2010 |
| 20100183482 | Microfluidics System for Mixing at Least Two Starting Materials - A microfluidics system for mixing at least two starting materials having a prescribed number of parallel and identical mixing or reaction branches, in which a number of supply ducts corresponding to the number of starting materials open into a mixing or reaction channel. Each of the supply ducts includes an intake line for each starting material, an injection pump for each supply duct and a valve circuit between each intake line for a starting material, where the supply ducts for a respective starting material and a respective injection pump are provided to each respective supply duct. The valve circuit is configured to connect the injection pumps to the suction line in a first valve position, shut off the injection pumps in a second valve position, and to connect the injection pumps to the associated inlet channels in a third valve position. Each of the injection pumps, which are connected to each valve circuit, have a common drive. All mixing or reaction branches connected in parallel can thus be supplied with the same volumetric flow of starting material. | 07-22-2010 |
| 20100247380 | Module for a Modular Microfluidic System - In order to be able to introduce fluid components extraneous to the system into a modular microfluidic system comprising modules arranged alongside one another which can be connected to one another with fluid connection by connecting parts comprising connecting channels with short connecting paths and good temperature controllability, a module with the following features is provided: the module has a plate-shaped microfluidic part which comprises a fluid channel system and on whose top side, in edge regions to the potentially adjacent modules of the microfluidic system has fluid connections, the fluidic connection to adjacent modules being establishable by means of the connecting parts adjacent in edge regions on the upper side, below the microfluidic part is arranged an insulation vessel which can be filled and flowed through by a temperature control fluid and is concluded at the to by the microfluidic part which serves as a lid. | 09-30-2010 |
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| 20100300585 | LOW-DENSITY STEEL HAVING GOOD DRAWABILITY - The invention relates to a hot-rolled ferritic steel sheet, the composition of the steel of which comprises, the contents being expressed by weight: 0.001≦C≦0.15%, Mn≦1%, Si≦1.5%, 6%≦Al≦10%, 0.020%≦Ti≦0.5%, S≦0.050%, P≦0.1%, and, optionally, one or more elements chosen from: Cr≦1%, Mo≦1%, Ni≦1%, Nb≦0.1%, V≦0.2%, B≦0.010%, the balance of the composition consisting of iron and inevitable impurities resulting from the smelting, the average ferrite grain size d | 12-02-2010 |
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| 20100113999 | PRESSURE SENSITIVE ADHESIVE COMPOSITION COMPRISING SALT - The present invention relates to a pressure sensitive adhesive composition comprising a continuous phase and a discontinuous phase wherein | 05-06-2010 |
| 20100191204 | MULTI-LAYERED ADHESIVE APPLIANCE - A body waste collecting device comprising an adhesive composite that fastens a collecting bag to the skin is disclosed. The adhesive composite is highly moisture resistant while still being water absorbing. The adhesive composite comprises at least three layers, a backing layer, a moisture absorbing layer and a thin layer of vapour permeable, low-absorbing adhesive layer. | 07-29-2010 |
| 20100198176 | ADHESIVE COMPONENT FOR OSTOMY DEVICES - A component for sealing a body opening and for use in combination with a body waste collecting device, said component comprises a soft adhesive composition wherein the soft adhesive composition comprises a liquid impermeable, moisture permeable adhesive composition. | 08-05-2010 |
| 20100204632 | PERMEABLE PRESSURE SENSITIVE ADHESIVE - The present invention relates to a pressure sensitive, hot melt processable adhesive composition comprising a polar plasticising oil and a polar polyethylene copolymer, and a layered adhesive construct and a medical device comprising the adhesive composition according to the invention. | 08-12-2010 |
| 20100204664 | BODY WASTE COLLECTING DEVICE - A body waste collecting device for attachment to the body comprising a collecting pouch comprising a first wall and a second wall, the pouch being attached to an adhesive wafer, wherein a central portion of the wafer constitutes a part of the first wall of the pouch, the wafer comprises a permeable backing layer, at least one layer of an absorbent adhesive layer wherein the wafer comprises a moisture impermeable layer at least in the central portion. | 08-12-2010 |
| 20100204665 | COLLECTING DEVICE FOR BODY FLUIDS - A body waste collecting device comprising a collecting pouch and an adhesive wafer for attachment to the body, said adhesive wafer comprising a backing layer and a first adhesive layer, said first adhesive layer comprising a liquid impermeable, moisture permeable adhesive composition wherein the adhesive wafer comprising an additional second adhesive for sealing around a body opening. | 08-12-2010 |
| 20100217215 | OSTOMY APPLIANCE WITH MULTIPLE RELEASE LINERS - An ostomy appliance for attachment to the stoma body comprising a soft adhesive wafer ( | 08-26-2010 |
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| 20110273526 | Video Call Handling - Solutions for facilitating enhanced video calling functionality. Embodiments include functionality for handling video calling through a communications hub. According to some embodiments, the communications hub is a user supersystem having multiple clients, each with an integrated camera and display, capable of seamlessly handing off video call functionality among the clients. Other embodiments integrate other functionality of the communications hub (e.g., web browsing, multimedia, etc.) into the video call environment. | 11-10-2011 |
| 20110276895 | Conversation Capture - Solutions for capturing and displaying conversation history for providing conversation capture functionality. Some such solutions use a user supersystem as a communications hub to capture and/or generate relevant information for enhancing conversations with contacts, including address book information, contact notes, conversation history information, and/or conversation anchors. The information may then be processed for display to the user via a graphical interface. | 11-10-2011 |
| 20110276898 | Integrated Messaging Interface - Solutions for providing an integrated, interactive graphical messaging interface, e.g., through a user supersystem as a communications hub. For example, interactions with the messaging interface may provide access to many different types of messaging functionality and multiple communications channels. Some solutions may intuitively list all the different types of messaging communications in a single integrated listing format with intuitive interaction design. | 11-10-2011 |
| 20110276903 | Integrated Multi-Modal Chat - Solutions for providing context-driven communications mode determinations. Some such solutions use a communications hub located in a home (e.g., a user supersystem) to facilitate context-driven, multi-modal communications. For example, a tablet system may be used as a graphical communications hub in a family's home, used by the family to communicate to and from the home via multiple communications modes (e.g., family chat, family activities, user-based messaging, etc.) over one or more communications channels. Determination of an appropriate mode for communications may be driven by contextual (rather that channel-based) factors relating to the communications. | 11-10-2011 |
| 20110276923 | Photo Stack - Solutions for providing iconography to entice users to interact with multimedia services. Some such solutions use a user supersystem as an interactive media enticement system. Dynamic, interactive “photo stack” iconography can presented on the user supersystem for enticing users to interact with multimedia functionality of the user supersystem. For example, a “photo stack” icon dynamically displays a “most recent” photo as a top photo on a virtual photo stack. In certain cases, clicking on the “photo stack” icon brings the user to a photo booth application, through which the user may create, edit, post, etc. photos. | 11-10-2011 |
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| 20110099189 | METHOD AND APPARATUS FOR EXPLORING CONNECTIONS OF A POLYMORPHIC NOTE - An approach is provided for exploring connections of a polymorphic note. A polymorphic note manager receives a request to display one or more polymorphic notes connected to a selected polymorphic note. In response to the request, the polymorphic note manager determining the one or more connected polymorphic notes and causes, at least in part, actions that result in display of the selected polymorphic note, the one or more connected polymorphic notes, corresponding connections between the selected polymorphic note and the one or more connection polymorphic notes, or a combination thereof. | 04-28-2011 |
| 20110099490 | METHOD AND APPARATUS FOR PRESENTING POLYMORPHIC NOTES IN A GRAPHICAL USER INTERFACE - An approach is provided for presenting polymorphic notes in a graphical user interface. A polymorphic note manager receives a request to display a plurality of polymorphic notes on a graphical user interface of a device. In response to the request, the polymorphic note manager determines an order of the plurality of polymorphic notes according to either an associated date or, if there is no associated date, a creation date corresponding to each of the plurality of polymorphic notes. The polymorphic note manager then causes, at least in part, actions that result in display of the plurality of polymorphic notes in the graphical user interface according to the determined order | 04-28-2011 |
| 20110273576 | Video Recording Environment - Solutions for providing an interactive and intuitive video environment. Some such solutions use a user supersystem as an interactive multimedia system, including various features relating to video capture and processing. In some cases, a “live video thumbnail” is provided as part of a media album application, for example, to entice users to capture video (e.g., a photo or video file) using components of the user supersystem. Other implementations facilitate video processing functionality, such as “best frame” selection and auto-cropping of video data. | 11-10-2011 |
| 20110276885 | MULTI-CLIENT LOCAL NETWORK BASE STATION - Systems and methods are described for providing integrated, interactive communications services among multiple client devices in a local network. In one embodiment, a supersystem provides interactive communications services within a local network through a tablet, a handset, and a base station. The tablet includes a first client and a first user interface configured to provide interactivity with first communications services. The handset includes a second client and a second user interface configured to provide interactivity with second communications services. The first and second clients are in communication with the local network and with each other (e.g., either directly, or through the base station or other path). The base station includes interface subsystems configured to removably couple with the tablet and/or handset. The supersystem may allow multiple client devices to be used in an integrative fashion to provide home management, messaging, videoconferencing, cloud network interaction, media sharing, and/or other functionality. | 11-10-2011 |
| 20110276901 | FAMILY CHAT - Systems and methods are described for handling graphical interfacing with a group conversation involving a communications hub and multiple member devices. Embodiments provide a “family chat” communications mode for facilitating a synchronous conversation among all the members of the designated family group. Typically, the conversation may involve a user supersystem (e.g., including one or more graphical communications devices) associated with the family and disposed with the family's local network, and member devices associated with each member of the family group (e.g., cell phones, etc). In some embodiments, the family chat conversation is displayed (e.g., rendered) as a substantially continuous feed graphically indicating the party contributing each message to the feed, the temporal relationship of the various contributions, and other useful information. | 11-10-2011 |
| 20110276904 | DOODLE-IN-CHAT-CONTEXT - Solutions for providing integrated media services, e.g., in the context of communications services offered through a user supersystem configured as an interactive graphical communications hub. For example, interactions with a messaging interface may provide access to media creation functionality, including doodle functionality, in the context of the messaging and/or in the context of other media. In one implementation, the communications interface allows a user to doodle in the context of an image file (e.g., a photo) while in the context of a chat application. | 11-10-2011 |
| 20110296354 | Content-Driven Navigation - Solutions for providing intuitive, content-driven navigation through communications and multimedia services offered through, e.g., a user supersystem as a communications hub. For example, in some implementations, various data flows are traversed to move between applications according to interactions with content on those screens, rather than by using icons. In some cases, a small, static set of icons is used to navigate between a set of landing screens representing broad categories of functionality. Within each landing screen environment, content is used to drive navigation to and through application functionality. | 12-01-2011 |
