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Aster
Jon Aster, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110213012 | Treatment of Cancers Characterized by Chromosomal Rearrangement of the NUT Gene - The present invention is directed, inter alia, to methods of treating NUT midline carcinoma (NMC) by administering compounds that promote increased histone acetylation. The invention also includes assay methods for determining the responsiveness of NMC to specific histone deacetylases and other compounds. | 09-01-2011 |
Jon C. Aster, Lexington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080241150 | Functional negative regulatory domain sequences from human NOTCH1 and 2 and isolated LNR domains from human NOTCH1 - The present invention relates to a LNR-HD domain of the Notch receptor and methods of use. The method for expression and structural determination of the LNR-HD domain is described. | 10-02-2008 |
| 20100087358 | NOTCH mutations leading to increased receptor signaling - The present invention is based upon the identification of regions within the NOTCH-1 receptor that, when mutated, lead to increase receptor signaling. The mutations are associated with uncontrolled cellular growth and this growth may be arrested using agents that interfere with NOTCH-1 activity, such as inhibitors of gamma-secretase. Assays for the NOTCH-1 mutations may be used diagnostically or as part of a treatment regimen for cancer patients. | 04-08-2010 |
Marcel Aster, La Ciotat FR
| Patent application number | Description | Published |
|---|---|---|
| 20080305521 | Method for Overproducing Specific Recombinant Protein with P. Cinnabarinus Monokaryotic Strains - The use of monokaryotic strains of filamentous fungi of the | 12-11-2008 |
Marius Aster, Naturns IT
| Patent application number | Description | Published |
|---|---|---|
| 20100058588 | Machining of Ceramic Materials - Milling strategies for machining dental ceramic materials are provided that reduce milling time while maintaining strength, accuracy and marginal integrity. | 03-11-2010 |
| 20110200966 | Machining of Ceramic Materials - Milling strategies for machining dental ceramic materials are provided that reduce milling time while maintaining strength, accuracy and marginal integrity. | 08-18-2011 |
Martin Aster, Salzburg AT
| Patent application number | Description | Published |
|---|---|---|
| 20100250389 | METHOD, SYSTEM, LICENSE SERVER FOR PROVIDING A LICENSE TO A USER FOR ACCESSING A PROTECTED CONTENT ON A USER DEVICE AND SOFTWARE MODULE - A method for providing a license to a user for accessing a protected content on a user device is provided, the method comprising: transmitting user authentication data from the user device to a user account server; transmitting user identification data from the user account server to a license server if the user authentication data corresponds to a valid user account on the user account server; checking in the license server, whether the user is entitled to the license; and transmitting the license from the license server to the user device, if the user identification data is validated and if the user is deemed entitled to the license. A corresponding system, a license server and a software module are provided as well. | 09-30-2010 |
Radek Aster, Sunnyvale, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090276566 | CREATING LOGICAL DISK DRIVES FOR RAID SUBSYSTEMS - A computer storage system includes multiple disk trays, each disk tray holding two or more physical disks. The disks on a single tray are virtualized into a single logical disk. The single logical disk reports to the RAID (redundant array of inexpensive disks) subsystem, creating the impression that there is one large capacity disk. In one implementation, each disk in the tray is allocated to a different RAID group. By allocating the disks in a tray to different RAID groups, if the tray is removed, only a portion of several different RAID groups are removed. This arrangement permits a simple reconstruction of the RAID groups if a disk tray is removed from the system. | 11-05-2009 |
Susan D. Aster, Teaneck, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20080255216 | Diaryltriazoles as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1 - 2,5-Diaryl-1,2,4-triazole derivatives of structural formula I are selective inhibitors of the 11&bgr;-hydroxysteroid dehydrogenase Type 1 enzyme (11&bgr;-HSD-1). The compounds are useful for the treatment of diabetes, hyperglycemia, obesity, insulin resistance, atherosclerosis, dyslipidemia, hyperlipidemia, hypertension, and Metabolic Syndrome. Also disclosed are novel compounds of structural formula II which are inhibitors of 11&bgr;-HSD-1. | 10-16-2008 |
| 20090181994 | TRIAZOLE DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1 - Triazole derivatives of structural formula I are selective inhibitors of the 11β-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other symptoms associated with NIDDM. | 07-16-2009 |
Walter J. Aster, Brentwood, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080287973 | VARIABLE PARIETAL/VISCERAL PLEURAL COUPLING - A variable parietal/visceral pleural coupling may be utilized to create an air-tight seal in the pleural space between the parietal and visceral pleura. This coupling may be utilized to create a seal for other implantable devices. | 11-20-2008 |