Aster
Denise Aster, Drexel Hill, PA US
Patent application number | Description | Published |
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20130203002 | Customizable Candle and Candle Holder - A customizable candle holder whose design is controlled by a user is described. The components of the candle holder comprise a base, a pillar, and a holder block. The components are designed such that the base supports the insertion of either the pillar or the holder block, and such that the pillar supports the insertion of the holder block. Therefore, the candle holder can be uniquely designed by a user with the incorporation of components of different or alternative designs. Candle holders of the invention can also comprise decorative charms, which can be removably attached to the holder thereby allowing more design freedom to the user. | 08-08-2013 |
Jon Aster, Lexington, MA US
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20110213012 | Treatment of Cancers Characterized by Chromosomal Rearrangement of the NUT Gene - The present invention is directed, inter alia, to methods of treating NUT midline carcinoma (NMC) by administering compounds that promote increased histone acetylation. The invention also includes assay methods for determining the responsiveness of NMC to specific histone deacetylases and other compounds. | 09-01-2011 |
20110286916 | GENERATION AND CHARACTERIZATION OF ANTI-NOTCH ANTIBODIES FOR THERAPEUTIC AND DIAGNOSTIC USE - The present invention relates to mammalian antibodies, preferably fully human monoclonal antibodies and antigen-binding portions thereof that specifically bind to a cell surface receptor, wherein the receptor protein is a Notch1 receptor protein. Some of the disclosed antibodies bind Notch1 to the exclusion of other members of the Notch receptor family, while other antibodies bind Notch 1 and Notch3. Nucleic acid molecules encoding the Notch antibodies as well as methods of use thereof are also disclosed. Also included are pharmaceutical compositions comprising these antibodies and methods of using the antibodies and compositions thereof for treatment and diagnosis of pathological hyperproliferative oncogenic disorders associated with expression of Notch1 or Notch3 including aberrant activation of each of these receptors. | 11-24-2011 |
Jon C. Aster, Lexington, MA US
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20080241150 | Functional negative regulatory domain sequences from human NOTCH1 and 2 and isolated LNR domains from human NOTCH1 - The present invention relates to a LNR-HD domain of the Notch receptor and methods of use. The method for expression and structural determination of the LNR-HD domain is described. | 10-02-2008 |
20100087358 | NOTCH mutations leading to increased receptor signaling - The present invention is based upon the identification of regions within the NOTCH-1 receptor that, when mutated, lead to increase receptor signaling. The mutations are associated with uncontrolled cellular growth and this growth may be arrested using agents that interfere with NOTCH-1 activity, such as inhibitors of gamma-secretase. Assays for the NOTCH-1 mutations may be used diagnostically or as part of a treatment regimen for cancer patients. | 04-08-2010 |
Marcel Aster, La Ciotat FR
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20080305521 | Method for Overproducing Specific Recombinant Protein with P. Cinnabarinus Monokaryotic Strains - The use of monokaryotic strains of filamentous fungi of the | 12-11-2008 |
Marius Aster, Naturns IT
Patent application number | Description | Published |
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20100058588 | Machining of Ceramic Materials - Milling strategies for machining dental ceramic materials are provided that reduce milling time while maintaining strength, accuracy and marginal integrity. | 03-11-2010 |
20110200966 | Machining of Ceramic Materials - Milling strategies for machining dental ceramic materials are provided that reduce milling time while maintaining strength, accuracy and marginal integrity. | 08-18-2011 |
20120219930 | Machining of Ceramic Materials - Milling strategies for machining dental ceramic materials are provided that reduce milling time while maintaining strength, accuracy and marginal integrity. | 08-30-2012 |
Martin Aster, Salzburg AT
Patent application number | Description | Published |
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20100250389 | METHOD, SYSTEM, LICENSE SERVER FOR PROVIDING A LICENSE TO A USER FOR ACCESSING A PROTECTED CONTENT ON A USER DEVICE AND SOFTWARE MODULE - A method for providing a license to a user for accessing a protected content on a user device is provided, the method comprising: transmitting user authentication data from the user device to a user account server; transmitting user identification data from the user account server to a license server if the user authentication data corresponds to a valid user account on the user account server; checking in the license server, whether the user is entitled to the license; and transmitting the license from the license server to the user device, if the user identification data is validated and if the user is deemed entitled to the license. A corresponding system, a license server and a software module are provided as well. | 09-30-2010 |
Radek Aster, Sunnyvale, CA US
Patent application number | Description | Published |
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20090276566 | CREATING LOGICAL DISK DRIVES FOR RAID SUBSYSTEMS - A computer storage system includes multiple disk trays, each disk tray holding two or more physical disks. The disks on a single tray are virtualized into a single logical disk. The single logical disk reports to the RAID (redundant array of inexpensive disks) subsystem, creating the impression that there is one large capacity disk. In one implementation, each disk in the tray is allocated to a different RAID group. By allocating the disks in a tray to different RAID groups, if the tray is removed, only a portion of several different RAID groups are removed. This arrangement permits a simple reconstruction of the RAID groups if a disk tray is removed from the system. | 11-05-2009 |
20150046610 | STORAGE MASTER NODE - Technology is provided for selecting a master node of a node group in a storage system. The technology can gather data regarding visibility of one or more storage devices of the storage system to one or more active nodes of the node group, determine a maximum visibility value for the node group and selecting an active node with associated visibility value equal to the maximum visibility value as the master node of the node group. | 02-12-2015 |
Radek Aster, Campbell, CA US
Patent application number | Description | Published |
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20130219101 | COMMUNICATION WITH TWO OR MORE STORAGE DEVICES VIA ONE SAS COMMUNICATION PORT - One or more techniques and/or systems are disclosed for enabling communication between a SAS communication port of a SAS communication component and multiple storage devices. In a first example, a first SAS to SATA bridge chip and a second SAS to SATA bridge chip may be configured to route data from a SAS communication component to multiple storage devices. In a second example, a SAS to SATA bridge chip and a port multiplier may be configured to route data from a SAS communication component to multiple storage devices. In a third example, a four port SAS to SATA bridge comprising two SAS ports and two SATA ports may be configured to route data from a SAS communication component to multiple storage devices. Supporting two or more storage devices with a single SAS communication port allows storage enclosures to increase storage capacity, while decreasing cost per slot. | 08-22-2013 |
20140143460 | COMMUNICATION WITH TWO OR MORE STORAGE DEVICES VIA ONE SAS COMMUNICATION PORT - One or more techniques and/or systems are disclosed for enabling communication between a SAS communication port of a SAS communication component and multiple storage devices. In a first example, a first SAS to SATA bridge chip and a second SAS to SATA bridge chip may be configured to route data from a SAS communication component to multiple storage devices. In a second example, a SAS to SATA bridge chip and a port multiplier may be configured to route data from a SAS communication component to multiple storage devices. In a third example, a four port SAS to SATA bridge comprising two SAS ports and two SATA ports may be configured to route data from a SAS communication component to multiple storage devices. Supporting two or more storage devices with a single SAS communication port allows storage enclosures to increase storage capacity, while decreasing cost per slot. | 05-22-2014 |
Susan D. Aster, Teaneck, NJ US
Patent application number | Description | Published |
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20080255216 | Diaryltriazoles as Inhibitors of 11-Beta-Hydroxysteroid Dehydrogenase-1 - 2,5-Diaryl-1,2,4-triazole derivatives of structural formula I are selective inhibitors of the 11&bgr;-hydroxysteroid dehydrogenase Type 1 enzyme (11&bgr;-HSD-1). The compounds are useful for the treatment of diabetes, hyperglycemia, obesity, insulin resistance, atherosclerosis, dyslipidemia, hyperlipidemia, hypertension, and Metabolic Syndrome. Also disclosed are novel compounds of structural formula II which are inhibitors of 11&bgr;-HSD-1. | 10-16-2008 |
20090181994 | TRIAZOLE DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1 - Triazole derivatives of structural formula I are selective inhibitors of the 11β-hydroxysteroid dehydrogenase-1. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other symptoms associated with NIDDM. | 07-16-2009 |
20120041012 | SUBSTITUTED SPIROCYCLIC AMINES USEFUL AS ANTIDIABETIC COMPOUNDS - Substituted spirocyclic amines of structural formula I are selective antagonists of the somatostatin sub-type receptor 5 (SSTR5) and are useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as Type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, metabolic syndrome, depression, and anxiety. | 02-16-2012 |
Walter J. Aster, Brentwood, CA US
Patent application number | Description | Published |
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20080287973 | VARIABLE PARIETAL/VISCERAL PLEURAL COUPLING - A variable parietal/visceral pleural coupling may be utilized to create an air-tight seal in the pleural space between the parietal and visceral pleura. This coupling may be utilized to create a seal for other implantable devices. | 11-20-2008 |