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Assaraf
Meneachem Assaraf, Lehavim IL
| Patent application number | Description | Published |
|---|---|---|
| 20100291230 | Novel Pesticide Compositions - Novel pesticide compositions and formulations, containing a phosphorous-containing compound and a nitrogen-releasing compound, are disclosed. These novel compositions exhibit a synergistic pesticidal activity and are particularly useful in treating pests such as nematodes (including root-not nematodes), fungi and bacteria. Methods utilizing these compositions for controlling pests, articles-of-manufacture containing same and processes of preparing same are further disclosed. | 11-18-2010 |
Yehuda Assaraf, D. N Misgav IL
| Patent application number | Description | Published |
|---|---|---|
| 20090298055 | PRODUCTION OF PROTEINS - The present invention is of a method of producing proteins in mammalian cells using a permanent selection in the absence of cytotoxic drugs. Specifically, the present invention can be used to produce large quantities of highly pure human proteins which are suitable for pharmaceutical applications. | 12-03-2009 |
Yehuda G Assaraf, Moshav Rakefet - Doar-Na Misgav IL
| Patent application number | Description | Published |
|---|---|---|
| 20110229892 | METHOD FOR PREDICTING A PATIENT'S RESPONSIVENESS TO ANTI-FOLATE THERAPY - A method of predicting responsiveness of a subject to a folylpolyglutamate synthetase (FPGS) dependent anti-folate is provided. The method comprises analyzing for a presence or absence of a splice variant of FPGS or a polypeptide encoded thereby, in a sample of the subject, wherein the presence of the splice variant or the polypeptide encoded thereby is indicative of a negative response to a FPGS-dependent anti-folate. Kits for prediction responsiveness of a subject to FPGS-dependent anti-folate are also disclosed. Antibodies specific for splice variants, the splice variant nucleic acids and polypeptides encoded by the splice variants are also claimed. In particular splice variants missing exons selected from the group of exon 3, exon 7, exon 10 and exon 12 are disclosed. | 09-22-2011 |
Yehuda G. Assaraf, Misgav IL
| Patent application number | Description | Published |
|---|---|---|
| 20110045092 | CASEIN PARTICLES ENCAPSULATING THERAPEUTICALLY ACTIVE AGENTS AND USES THEREOF - Casein particles, such as micelles or clusters thereof, having encapsulated therein hydrophobic and/or water insoluble therapeutically active agents such as hydrophobic chemotherapeutic agents, which are otherwise administered parenterally, are disclosed. Pharmaceutical compositions containing the casein particles and uses thereof in the treatment of cancer and other conditions treatable by the encapsulated therapeutically active agent are also disclosed. Further disclosed are processes of preparing the casein particles. The disclosed casein particles are useful for orally delivering the therapeutically active encapsulate and can further be used for controllably releasing the agents in the gastrointestinal tract. | 02-24-2011 |
Yehuda G. Assaraf, D.n. Misgav IL
| Patent application number | Description | Published |
|---|---|---|
| 20100330572 | ORGANIC COMPOUNDS - The present invention relates to a novel selection system for use in a eukaryotic cell culture process and for expression of a recombinant product of interest. The selection system is based on the introduction of an exogenous functional membrane-bound folate receptor gene together with the polynucleotide or gene encoding the product of interest into a eukaryotic cell and can be widely utilized with eukaryotic cells for which cellular viability is dependent upon folic acid uptake. | 12-30-2010 |
Yehuda G. Assaraf, Doar-Na Misgav IL
| Patent application number | Description | Published |
|---|---|---|
| 20100137351 | Imidazoacridinone derivative compounds and methods for their use - The present invention provides IA derivative compounds of the formula: | 06-03-2010 |