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Asa Abeliovich, New York, NY US

Patent application numberDescriptionPublished
20090004112METHODS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES USING NMDA RECEPTOR GLYCINE SITE ANTAGONISTS - The disclosure provides methods for treating a neurodegenerative disease by administering a NMDA receptor glycine site antagonist. Compounds that can be used in the methods are also provided. Methods are also provided for determining whether a compound inhibits activity of a Parkinson's Disease-associated mutant of leucine-rich repeat kinase-2 (LRRK2). The methods include assessing accumulation of axonal spheroid inclusions, branching and length of neuronal processes, and neuronal cell death.01-01-2009
20110189308METHODS TO TREAT NEURODEGENERATIVE CONDITIONS OR DISEASES BY TARGETING COMPONENTS OF A PTEN SIGNALING PATHWAY - The disclosure provides that components of a PTEN cell signaling pathway may be utilized as therapeutic targets for treating, preventing, slowing the progression of or delaying the onset of a neurodegenerative disease or disorder. Such components that may be targeted include, phosphatase and tensin homologue (PTEN), glycogen synthase kinase 3 beta (GSK3β), and AKT. The subject matter disclosed herein relates to the therapeutic use of inhibitors of PTEN, inhibitors of GSK3β, or activators of AKT to treat a neurodegenerative disease or disorder in a subject. Compounds are disclosed which may be used in the methods provided.08-04-2011

Patent applications by Asa Abeliovich, New York, NY US

Asa Bertze, Stockholm SE

Patent application numberDescriptionPublished
20110222414METHOD AND APPARATUS FOR ACTIVE PROBING OF TUNNELED INTERNET PROTOCOL (IP) TRANSMISSION PATHS - A method, apparatus, and system in an IP-based mobile communication network for actively probing a tunneled transmission path from a base station such as an eNB to a core network. A UE-emulator emulates a User Equipment (UE) and provides emulated NAS signaling to a Probe Connection Control (PCC) unit in the base station, which establishes the tunneled transmission path by forwarding the NAS signaling received from the emulator toward the core network. The PCC stores associated communication endpoints and UE-assigned IP addresses. A Probe Traffic Control (PTC) unit within the base station utilizes the stored endpoints and IP addresses to generate probe traffic through the tunneled transmission path toward a probe server or another base station configured as a probe reflector. The probe reflector collects and reports path properties such as packet loss, delay, jitter, and throughput.09-15-2011

Asa Brynjolfsdottir, Kopavogur IS

Patent application numberDescriptionPublished
20090311348PHARMECEUTICAL AND COSMETIC USE OF SILICA - The invention provides the use of silica for cosmetic and/or medical treatment of skin, including improving and enhancing the skin-barrier, anti-aging treatment and photo-protective treatment. The invention is based on the finding that silica exhibits a multi-faceted biological effect useful in the cosmetic and/or therapeutic treatment of skin for the above purposes. Specifically, it has been shown that silica induces markers (involucrin, filaggrin and transglutaminase-1) for skin barrier formation in keratinocytes, induces collagen expression in dermal fibroblasts and inhibits UVA-induced up-regulation of photo-aging markers (matrix metalloproteinase MMP-1 and cytokine IL-6).12-17-2009
20100028376PHARMACEUTICAL AND COSMETIC USE OF EXTRACTS FROM ALGAE OBTAINABLE FROM SALINE HOT WATER SOURCES - The invention provides the use of extracts from algae for cosmetic and/or medical treatment of skin, including improving and enhancing the skin-barrier, anti-aging treatment and photo-protective treatment. The invention is based on the finding that extracts from algae obtainable from saline hot water sources exhibit a multi-faceted biological effect useful in the cosmetic and/or therapeutic treatment of skin for the above purposes. Specifically, it has been shown that such algae extracts induce markers (involucrin, filaggrin and transglutaminase-1) for skin barrier formation in keratinocytes, induce collagen expression in dermal fibroblasts and inhibit UVA-induced up-regulation of photo-aging markers (matrix metalloproteinase MMP-1 and cytokine IL-6).02-04-2010

Asa Christiander, Nacka SE

Patent application numberDescriptionPublished
20110227746DOOR CONTROL APPARATUS - A door control apparatus and methods for controlling a door motion device for a hinged door and, optionally, illuminating a designated area on the floor. During the time the designated area is illuminated, a person can expect that the door will not close. The door control apparatus may include control circuitry, and a sensor, and optionally a light emitter and/or a sound emitter. The sensor detects a person proximate to the door and signals the control circuitry upon a detection event. The light emitter is also connected to the control circuitry. Upon a detection event, the control circuitry signals the light emitter to produce light and signals the door motion device to hold the door open. The light emitter directs light to form an image on the floor in the designated area. The light emitter may be, for example, a laser generator or a light emitting diode lamp.09-22-2011

Asa Frostell-Karlsson, Uppsala SE

Patent application numberDescriptionPublished
20110070574METHOD FOR VIRUS DETECTION - A method of determining the concentration of a virus or antigen thereof in a sample comprises the steps of: providing a sensor surface having immobilized thereto a virus antigen or a virus antigen analogue, mixing the sample with a known amount of antibody to the virus antigen to obtain a predetermined concentration of antibody to the antigen in the sample mixture, contacting the sample mixture with the sensor surface to bind free antibody in the mixture to the sensor surface, measuring the response of the sensor surface to the binding of free antibody, and determining the concentration of the virus or antigen in the sample from a calibration curve prepared by measuring the responses obtained for mixtures containing the predetermined concentration of antibody and different concentrations of virus.03-24-2011
20110076703CONCENTRATION ASSAY - A method of determining the concentration of at least one analyte in a plurality of samples by sequentially subjecting each sample to an analysis cycle comprises contacting the sample or a sample-derived solution with a sensor surface supporting a species capable of specifically binding the analyte or an analyte-binding species, detecting the amount of binding to the sensor surface, and regenerating the sensor surface to prepare it for the next analytical cycle, and based on the detected binding to the sensor surface determining the concentration of analyte in each sample using virtual calibration data calculated for each analysis cycle from real calibration data obtained by contacting the solid phase with samples containing known concentrations of analyte.03-31-2011

Asa Gronqvist, Vasteras SE

Patent application numberDescriptionPublished
20100085671ARC MONITOR - An arc monitor for tripping a circuit breaker in the event of an arc occurrence, the arc monitor including at least one arc detector and arranged to be operatively connected to at least one circuit breaker. The arc monitor includes a base unit and at least one extension unit with at least one arc detector input terminal, the at least one arc detector being connectable to the at least one arc detector input terminal, and the base unit includes a control unit. The extension unit is operatively connectable to and arranged to send an arc occurrence signal to the control unit, which is arranged to send a trip signal for tripping the at least one circuit breaker, in the event of an arc occurrence. Also an electrical installation including an arc monitor, and the use of an arc monitor as a supervision and safety equipment in an electrical installation.04-08-2010

Asa Hagner-Mcwhirter, Uppsala SE

Patent application numberDescriptionPublished
20080314750Method for Pre-Fractionation of Complex Samples - The present invention relates to a method for pre-fractionation of complex protein and/or peptide samples. The method comprises the following steps: 12-25-2008

Asa Karlsson, Sollentuna SE

Patent application numberDescriptionPublished
20100196356Tumour Growth Inhibitory Compounds and Methods of their Use - Specific CpG oligonucleotide sequences, when given subcutaneously and in particular when administered on a mucous membrane, e.g. intranasally, intravaginally, or rectally, have a profound effect on various human cancer forms as confirmed in vivo, in animal studies, and in vitro, in human PBMCs collected from blood from healthy subjects and from patients suffering from CLL or FL. The compounds are also preferably used in combination with a cancer therapy chosen among radiation treatment, hormone treatment, surgical intervention, chemotherapy, immunological therapies, photodynamic therapy, laser therapy, hyperthermia, cryotherapy, angiogenesis inhibition, or a combination of any of these, and is most preferably an immunological treatment and comprises the administration of an antibody to the patient.08-05-2010

Asa Lennersten, Molndal SE

Patent application numberDescriptionPublished
20090036849Absorbent Article - An absorbent article such as a sanitary napkin, panty liner, tampon, diaper, pant diaper, adult incontinence guard, provided with at least one capsule (02-05-2009

Asa Ljungh, Lund SE

Patent application numberDescriptionPublished
20100330141PRODUCT FOR ABSORPTION PURPOSES - A product for absorption purposes comprises a water insoluble support matrix substituted with a hydrophobic entity and a positively charged entity. The hydrophobic entity comprises di-alkyl carbamoyl chloride (DACC) and the positively charged entity comprises polyethyleneimine (PEI). The product is capable of removing microorganisms, including viruses, from air and liquid. Methods for manufacturing the product and uses and applications of the product are also presented.12-30-2010

Asa Persson, Taastrup DK

Patent application numberDescriptionPublished
20100119886METHOD OF PRODUCING A MULTILAYER BARRIER STRUCTURE FOR A SOLID OXIDE FUEL CELL - The present invention provides a method of producing a multilayer barrier structure in a solid oxide cell stack, comprising the steps of: -providing a metal interconnect; -applying a first metal oxide layer on said metal interconnect; -applying a second metal oxide layer on top of said first metal oxide layer; -applying a third metal oxide layer on top of said second metal oxide layer; -forming a solid oxide cell stack comprising said metal interconnect having said metal oxide layers thereon; and -reacting the metal oxide in said first metal oxide layer with the metal of said metal interconnect during the SOC-stack initialisation, and a solid oxide stack comprising an anode contact layer and support structure, an anode layer, an electrolyte layer, a cathode layer, a cathode contact layer, a metallic interconnect, and a multilayer barrier structure which is obtainable by the above method and through an initialisation step, which is carried out under controlled conditions for atmosphere composition and current load, which depends on the layer composition facilitating the formation of the desired reaction products as a dense barrier layer without chromium species migrating to the air-electrode.05-13-2010

Asa Rudstedt, Uppsala SE

Patent application numberDescriptionPublished
20100059440CROSS-LINKED CELLULOSE MEMBRANES - The invention relates to a process for making porous cross-linked charged cellulosic polymeric membranes capable of binding to a target molecule. The invention provides methods for separating target molecules from other components in a solution comprising use of membranes obtainable by the process of the invention. The method has particular utility in separating proteins and nucleic acids from cell lysates and cultures.03-11-2010

Asa Whillock, San Francisco, CA US

Patent application numberDescriptionPublished
20090097651IMPARTING CRYPTOGRAPHIC INFORMATION IN NETWORK COMMUNICATIONS - This specification describes technologies relating to imparting cryptographic information in network communications. In general, aspects of the subject matter described in this specification can be embodied in methods that include identifying a location in a pre-defined portion of a network communication to be sent in a client-server environment, wherein the pre-defined portion is reserved for random data, inserting cryptographic information into the pre-defined portion of the network communication at the location, and sending the network communication in the client-server environment to facilitate modifying interactions in the client-server environment based at least in part on a result of processing of the cryptographic information; and on a receiving side, receiving cryptographic information inserted into the pre-defined portion of the network communication in the client-server environment, identifying the location, processing the cryptographic information, and modifying interactions in the client-server environment based at least in part on a result of the processing.04-16-2009
20100057928Dynamically Altering Playlists - In general, in one aspect, streams associated with a playlist are received from a server. The playlist includes an ordering of streams that are queued for client-side playback from the server according to the ordering. Information associated with the receipt and playback of at least one of the streams is accessed. The client-side application requests to alter the streams of the playlist in response to the accessed information. The request identifies a desired playlist alteration and includes information that controls the playlist alteration. The streams of the playlist are displayed according to a playlist alteration made in response to the request.03-04-2010
20100095121IMPARTING REAL-TIME PRIORITY-BASED NETWORK COMMUNICATIONS IN AN ENCRYPTED COMMUNICATION SESSION - This specification describes technologies relating to imparting real-time priority-based network communications in an encrypted session. In general, aspects of the subject matter described can be embodied in methods that include establishing, based on cryptographic information in a reserved, random-data portion of a handshake communication, a session, receiving parameter values relating to a sub media stream, included in a header of a network communication, storing the parameter values, obtaining state information and a data payload included in a second network communication, identifying, from the state information, a purpose of the second network communication, and whether a header of the second network communication includes one or more new values corresponding to one or more of the parameters, updating one or more of the stored values based on the one or more new values, and processing the data payload based on the identified purpose and the stored parameter values.04-15-2010