| Patent application number | Description | Published |
|---|
| 20080207527 | Bicyclic Compounds Which Inhibit Beta-Secretase Activity and Methods of Use Thereof - The present invention provides bicyclic beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer's disease. | 08-28-2008 |
| 20100041619 | Lasonolide compounds as reagents for inducing premature chromosome condensation and methods for treating disorders - The present invention is directed towards lasonolide derivatives, methods of inducing premature chromosome condensation using lasonolide derivatives, and methods of treating disorders, such as cancer, in a subject, the method comprising administering to the subject a lasonolide derivative. | 02-18-2010 |
| 20100113582 | METHODS AND COMPOSITIONS FOR TREATING HIV INFECTIONS - Described herein are compounds and compositions that are useful in the treatment of HIV, AIDS, and AIDS-related diseases. In addition, compounds are described herein that are capable of inhibiting the dimerization of HIV proteases. | 05-06-2010 |
| 20100267609 | COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF - Compounds inhibit memapsin 2 β-secretase activity and selectively inhibit memapsin 2 β-secretase activity relative to memapsin 1 β-secretase activity. The compounds are employed in methods to inhibit memapsin 2 β-secretase activity, in the treatment of Alzheimer's disease, in the inhibition of hydrolysis of a β-secretase site of a β-amyloid precursor protein and to decrease β-amyloid protein in in vitro samples and in mammals. Proteins of memapsin 2 associated with compounds of the invention are crystallized. | 10-21-2010 |
| 20100286145 | ISOPHTHALAMIDE DERIVATIVES INHIBITING BETA-SECRETASE ACTIVITY - The present invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer's disease. | 11-11-2010 |
| 20100286170 | (3-HYDROXY-4-AMINO-BUTAN-2-YL) -3- (2-THIAZOL-2-YL-PYRROLIDINE-1-CARBONYL) BENZAMIDE DERIVATIVES AND RELATED COMPOUNDS AS BETA-SECRETASE INHIBITORS FOR TREATING - The present invention provides novel beta-secretase inhibitors and methods for their use, including methods of treating of Alzheimer's disease. | 11-11-2010 |
| 20110046199 | SMALL MOLECULE INHIBITORS OF HIV PROTEASES - Described herein are compounds, compositions, and methods for treating HIV and related diseases. | 02-24-2011 |
| 20110118330 | HIV PROTEASE INHIBITORS AND METHODS FOR USING - Compounds that inhibit proteolytic enzymes of Human Immunodeficiency Virus (HIV) are described. Preparation of the inhibitors, pharmaceutical compositions containing them, and uses of the compounds or compositions for the treatment of HIV infections are also described. | 05-19-2011 |
