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Artis Deloney, Flint, MI US

Patent application numberDescriptionPublished
20080282620PORTABLE BAR-B-Q PLATFORM - A portable deck adapted for outdoor use includes a base forming a floor with retaining rails attached by hinges to a side and an end of the base pivotable between a use position extending upwardly and a storage position folded toward the floor. The deck may be supported on a plurality of extendable-retractable wheels. A foldably supported shelf may be attached to the top of at least one of the rails. Brace members with pivoting central joints may be angularly disposed between the deck floor and a post that forms the rail assembly to support it in an upright position and between a post and a shelf to hold it in a level position. Alternatively, a locking rod is positioned in brackets attached to the deck perimeter to entrap the rails between the rod and the deck to releasably retain them in an upright position.11-20-2008

Artis Klapars, Edison, NJ US

Patent application numberDescriptionPublished
20090247770PROCESS FOR MAKING LACTAM TACHYKININ RECEPTOR ANTAGONISTS - The present invention is directed to a process for preparing α,α disubstituted γ-lactam derivatives of formula (I) that are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The compounds are useful in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.10-01-2009
20100292282SYNTHESIS AND CRYSTALLINE FORMS OF CB-1 ANTAGONIST/INVERSE AGONIST - The present invention relates to a process for producing crystalline 3-[(1S)-1-(1-{(S)-(4-chlorophenyl)[3-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)phenyl]methyl}azetidin-3-yl)-2-fluoro-2-methyl-propyl]-5-fluorobenzonitrile, and novel salts, solvates, hydrates and polymorphs thereof.11-18-2010

Artis Klapars, Scotch Plains, NJ US

Patent application numberDescriptionPublished
20090018340Formation of Tetra-Substituted Enamides and Stereoselective Reduction Thereof - The present invention is directed to a practical process for the preparation of an enamide (II) by palladium catalyzed coupling of a primary amide (IV) with a compound of structural formula (III), as shown below: As well as to crystalline forms of a compound produced by this process, in particular, an anhydrous crystal form, Form B, and crystalline solvates falling into three patterns, Type 1, Type 2, and Type 3, and crystalline intermediate compounds produced in the process. Still further, the present invention relates to the stereoselective reduction of the tetrasubstituted enamide (II) to the corresponding amide (I).01-15-2009
20100041893FORMATION OF TETRA-SUBSTITUTED ENAMIDES AND STEREOSELECTIVE REDUCTION THEREOF - The present invention is directed to a practical process for the preparation of an enamide (II) by palladium catalyzed coupling of a primary amide (IV) with a compound of structural formula (III), as shown below: As well as to crystalline forms of a compound produced by this process, in particular, an anhydrous crystal form, Form B, and crystalline solvates falling into three patterns, Type 1, Type 2, and Type 3, and crystalline intermediate compounds produced in the process. Still further, the present invention relates to the stereoselective reduction of the tetrasubstituted enamide (II) to the corresponding amide (I).02-18-2010

Patent applications by Artis Klapars, Scotch Plains, NJ US