Aronow

Bruce Aronow, Cincinnati, OH US

Patent application number	Description	Published
20100267575	GENE ARRAY TECHNIQUE FOR PREDICTING RESPONSE IN INFLAMMATORY BOWEL DISEASES - Disclosed are methods for classifying individuals having or suspected of having an inflammatory bowel disease, such as Crohn's Disease or Ulcerative Colitis, as “responders” or “non-responders” to first-line treatment, generally comprising the steps of a) obtaining, a biological sample from the individual, b) isolating mRNA from the biological sample c) determining a gene expression profile from the biological sample; and d) comparing the gene expression profile of the individual to a reference gene expression profile or other suitable control such that changes in expression can be used to stratify individuals and predict efficacy of first-line therapy. A gene expression system is further provided for carrying out these methods.	10-21-2010

Patent application number	Description	Published
20090136591	METALLOTHIONEIN AS AN EARLY BIOMARKER FOR DEATH SECONDARY TO SEPTIC SHOCK AND AS A NOVEL THERAPEUTIC TARGET FOR SEPTIC SHOCK - A set of signature genes that predict the severity of septic shock, as well as methods of diagnosing and treating septic shock. The genes and methods are particularly useful for the identification of individuals who are at a high risk of death from septic shock.	05-28-2009

Patent application number	Description	Published
20090112204	Multiple Parameter Fault Detection in Electrosurgical Instrument Shields - A system and method for detecting faults within an electrosurgical instrument having a shield and an active electrode uses multiple possible fault conditions. In one embodiment the monitoring system comprises an electrosurgical generator coupled to the electrosurgical instrument and adapted to deliver power to the active electrode of the electrosurgical instrument, monitoring circuitry coupled to the electrosurgical generator and the electrosurgical instrument, wherein the monitoring circuitry comprises an active electrode voltage sensor an active electrode current sensor and a shield current sensor. The monitoring circuitry measures at least two of the active voltage, the active or return electrode current, and the shield current.	04-30-2009