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Arndt, AU
Gregory Arndt, New South Wales AU
| Patent application number | Description | Published |
|---|---|---|
| 20100260675 | Oxytocin Receptor Antagonists and Their Use for the Treatment of Pulmonary Related Diseases - Methods of treating disorders related to Oxytocin Receptor activity utilize OXYTOCIN RECEPTOR antagonists, such as antibodies, including specified portions or variants, polypeptides, polynucleotides, small molecule drugs, siRNA, shRNA, and DNAzymes. Disorders related to Oxytocin Receptor activity include inflammatory disorders, such as pulmonary disorders, for example, asthma, emphysema, and COPD. | 10-14-2010 |
Gregory M. Arndt, Sydney AU
| Patent application number | Description | Published |
|---|---|---|
| 20100075304 | PROCESS FOR MONITORING COLORECTAL CANCER - Disclosed in this specification is a method for determining the stage of colorectal cancer by observing regulatory changes in select miRNA sequences. These sequences may include hsa-miR-31, hsa-miR-7, hsa-miR-99b, hsa-miR-378*, hsa-miR-133a, hsa-miR-125a and combinations of these sequences. | 03-25-2010 |
Gregory M. Arndt, New South Wales AU
| Patent application number | Description | Published |
|---|---|---|
| 20090028862 | Emmprin antagonists and uses thereof - EMMPRIN (Extracellular Matrix Metalloproteinase Inducer) antagonists, such as antibodies, including specified portions or variants, siRNA, shRNA, antisense and DNAzymes, can be used to treat pathological processes associated with proliferative diseases, such as cancer, by specifically preventing or inhibiting the ability of proliferating tissue to develop a blood supply. | 01-29-2009 |
Gregory Martin Arndt, New South Wales AU
| Patent application number | Description | Published |
|---|---|---|
| 20090192103 | Multitargeting Interfering RNAs Having Two Active Strands And Methods For Their Design And Use - Interfering RNA molecules are now designed and produced with specificity for multiple binding sequences present in distinct genetic contexts in one or more pre-selected target RNA molecules and are used to modulate expression of the target sequences. The multitargeting interfering RNA molecules have two strands that target multiple target sites on one or more pre-selected RNA molecules. Such a multitargeting interfering RNA approach provides a powerful tool for gene regulation. | 07-30-2009 |
| 20090239816 | Multitargeting Interfering RNAs And Methods Of Their Use And Design - Interfering RNA molecules are now designed and produced with specificity for multiple binding sequences present in distinct genetic contexts in one or more pre-selected target RNA molecules and are used to modulate expression of the target sequences. Such a multitargeting interfering RNA approach provides a powerful tool for gene regulation. | 09-24-2009 |
| 20100286238 | SUPPRESSION OF VIRUSES INVOLVED IN RESPIRATORY INFECTION OR DISEASE - The present invention concerns methods and reagents useful in decreasing the level of or severity of respiratory infection or disease due to paramyxoviruses, such as RSV or HPIV, or coronavirus infection. Particularly, the invention relates to modulating gene expression using a multitargeting interfering RNA molecules that target multiple target sites on one or more pre-selected RNA molecules. | 11-11-2010 |
| 20100305186 | METHODS FOR MEDIATING GENE SUPPRESSION - The present invention is concerned with methods for enhancing gene suppression in cells and in particular it is concerned with improved methods for enhancing RNAi-mediated gene silencing by manipulation of factors associated with RNAi. The present invention is also concerned with methods for identifying factors which down-regulate as well as those which up-regulate RNAi. It is also concerned with genetic constructs useful for enhancing or modulating gene silencing and cells harbouring such constructs. | 12-02-2010 |
| 20110098200 | Methods using dsdna to mediate rna interference (rnai) - The present invention provides methods of producing dsDNA molecules that can be used to mediate RNA interference (RNAi). These methods include the production of hairpin DNAs including random sequences, and the use of convergent promoters to co-express sense and antisense RNAs. As such, the invention allows the production of random short hairpin RNA (shRNA) and a small interfering RNA (siRNA) expression libraries for forward genetic screening. | 04-28-2011 |