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Armistead
David Armistead, Sudbury, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110130387 | SIRTUIN MODULATING COMPOUNDS - Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent. | 06-02-2011 |
David M. Armistead, Sudbury, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090221612 | CERTAIN SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF - Certain chemical entities chosen from compounds represented by Formula I and pharmaceutically acceptable salts and mixtures thereof, are provided herein. Pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include cancer (e.g., B-cell lymphoma and leukemia), autoimmune diseases, inflammatory diseases, acute inflammatory reactions, and allergic disorders. Methods of treatment include administering at least one chemical entity as a single active agent or administering at least one chemical entity in combination with one or more other therapeutic agents. Also provided are methods for determining the presence or absence of Syk kinase in a sample. | 09-03-2009 |
Jason Armistead, Avon, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20120066356 | SYSTEM AND METHOD FOR AUTOMATICALLY ADDRESSNG DEVICES ON A COMMUNICATION NETWORK - A system and method automatically assigns unique addresses to devices connected on a communication bus based on the parameters measured by each device. Assignment of addresses may be provided centrally by a controller or may be distributed, in which each device negotiates with other devices to assign unique addresses to each device. | 03-15-2012 |
John A. Armistead, Easley, SC US
| Patent application number | Description | Published |
|---|---|---|
| 20100132170 | Bow retainer clips for shoes - Standard bow knots—which are favored on lace-up shoes—are prone to come untied. The latter is both an inconvenience and a safety issue. But no bow knot can come untied until one end of the bow has passed back through the loosened knot. The present bow retainer clips are unitary, bent wire, spring clips which fit through the upper grommets of lace-up shoes. Such clips have recesses which are aligned with a row of grommets on either the left or right side of a shoe. While the bow knot is being tied, one or both halves of the bow on either side of the knot are inserted under the clip. The wire of the latter will indent and grip the shoelace so as to make it difficult or impossible for such to be pulled back through the knot. But by deliberately removing the bow portions from under the bow retaining clips, the bows can be untied in a conventional manner. These functional bow retainer clips are small and decorative, and can be used as attachment points for jewelry charms, if desired. | 06-03-2010 |
John Anderson Armistead, Easley, SC US
| Patent application number | Description | Published |
|---|---|---|
| 20100095547 | Instant reading oil dipstick - The present instant reading oil dipstick automatically extracts a representative column of oil from the crankcase oil reservoir. Such is done inside of a translucent fluoroplastic tube. A machined brass slide valve, with sealing O-rings, fits inside of the metal dipstick tubing leading into the engine crankcase. When the dipstick is withdrawn for checking oil level, the slide valve automatically closes over an air vent in the plastic tubing, thus preventing the oil that is inside the bottom of the tubing from running out. The oil level can be ascertained, easily—even in low light levels—without having to wipe off the oil from the outside of the dipstick, and without having to reinsert the dipstick one or more times. | 04-22-2010 |
| 20100139109 | Instant reading oil dipstick - The present instant reading oil dipstick automatically extracts a representative column of oil from the crankcase oil reservoir. Such is done inside of a translucent fluoroplastic tube. A machined brass slide valve, with sealing O-rings, fits inside of the metal dipstick tubing leading into the engine crankcase. When the dipstick is withdrawn for checking oil level, the slide valve automatically closes over an air vent in the plastic tubing, thus preventing the oil that is inside the bottom of the tubing from running out. The oil level can be ascertained, easily—even in low light levels—without have to wipe off the oil from the outside of the dipstick, and without having to reinsert the dipstick one or more times. | 06-10-2010 |
| 20110061254 | Instant reading oil dipstick improvements - Instant Reading Oil Dipstick Improvements is a near universal design with most assembly done by the manufacturer. The customers can easily adapt such to match their existing dipstick geometry by pushing the adjustable parts to the correct location, where they will remain. The air valve is within a single, machined brass cone that adapts to the metal tube and seals in the engine vacuum. A new tubular plastic air seal around the wire handle increases reliability. And a cone shaped rubber squeegee will automatically remove oil from the outside of the tubing as the dipstick is withdrawn from the crankcase. | 03-17-2011 |
| 20110245810 | Intermittently wholly indwelling, user-actuated, continually-retained, valved urinary catheter - Problems associated with prostate enlargement can be negated by using the present valved catheter. Such can be inserted and removed by the user. The catheter is retained in place by a flexible, foldable tee bar attached to the valve plug, which in turn is attached to a stretchy Nylon line. To actuate the valve, the plug can be pulled out of the upper catheter simply by pulling on the distal end of the catheter, allowing urine to drain. When the user has an erection, the penis engulfs the entire valved catheter. That helps to assure that reproductive functions will not be affected. | 10-06-2011 |