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Arinzeh
Treena Arinzeh, West Orange, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100233234 | System and method for a hydrogel and hydrogel composite for cartilage repair applications - The embodiments and examples provided herein are put forth so as to provide those of ordinary skill in the art with a complete disclosure and description of how to make and use the present invention, and are not intended to limit the present invention relates to compositions and methods of preparing a hydrogel comprising a water soluble cellulose compound, as well as preparing a three-dimensional matrix of micron sized electrospun fibers, wherein the electrospun fibers are formed from a electrospun composite comprising a water soluble cellulose compound. The matrix provides a scaffold supporting and promoting cartilage regeneration and repair. | 09-16-2010 |
| 20100324697 | System and method for a piezoelectric scaffold for nerve growth and repair - Provided is an electroactive structure for growing isolated differentiable cells comprising a three dimensional matrix of fibers formed of a biocompatible synthetic piezoelectric polymeric material, wherein the matrix of fibers is seeded with the isolated differentiable cells and forms a supporting scaffold for growing the isolated differentiable cells, and wherein the matrix of fibers stimulates differentiation of the isolated differentiable cells into a mature cell phenotype on the structure. | 12-23-2010 |
| 20110274742 | Cartilage Repair Systems and Applications Utilizing A Glycosaminoglycan Mimic - The present invention relates to hydrogel or scaffold compositions and methods of use for cell growth and/or regenerative medicine. The hydrogel comprises a water soluble cellulose compound and, in certain aspects, a fibrous or filamentous matrix. The hydrogels as described provide a support or scaffold that promotes, facilitates, and/or enhances progenitor or stem cell growth and/or differentiation. In addition, the hydrogel is useful for tissue, e.g., cartilage, regeneration and repair. | 11-10-2011 |
Treena Arinzeh, Jersey City, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100233807 | Substrate Recognition By Differentiable Human Mesenchymal Stem Cells - The invention described herein provides a structure for growing isolated differentiable human mesenchymal cells, which includes a three-dimensional matrix of fibers. The matrix serves as an implantable scaffolding for delivery of differentiable human mesenchymal cells in tissue engineering. The invention further provides compositions that contain the three-dimensional matrix of fibers seeded with isolated differentiable human mesenchymal cells, wherein the matrix forms a supporting scaffold for growing the isolated differentiable human mesenchymal cells, and wherein the differentiable human mesenchymal cells differentiate into a mature cell phenotype. The invention further provides methods of preparing the implantable nanofiber matrix scaffolding seeded with differentiable human mesenchymal cells for use in tissue engineering. | 09-16-2010 |
Treena L. Arinzeh, West Orange, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090325296 | ELECTROSPUN ELECTROACTIVE POLYMERS FOR REGENERATIVE MEDICINE APPLICATIONS - Due to the size and complexity of tissues such as the spinal cord and articular cartilage, specialized constructs incorporating cells as well as smart materials may be a promising strategy for achieving functional recovery. Aspects of the present invention describe the use of an electroactive, or piezoelectric, material that will act as a scaffold for stem cell induced tissue repair. Embodiments of the inventive material can also act alone as an electroactive scaffold for repairing tissues. The piezoelectric material of the present invention acts as a highly sensitive mechanoelectrical transducer that will generate charges in response to minute vibrational forces. | 12-31-2009 |
Treena Lynne Arinzeh, Newark, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090028921 | Electrospun Ceramic-Polymer Composite As A Scaffold For Tissue Repair - The present invention relates to compositions and methods of preparing a three-dimensional matrix of micron sized electrospun fibers, wherein the electrospun fibers are formed from a electrospun composite comprising a bioactive ceramic component and a polymer component. The matrix provides an osteoconductive and osteoinductive scaffold supporting osteogenesis and thereby facilitates bone repair. | 01-29-2009 |
Treena Lynne Arinzeh, West Orange, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20110300626 | Electrospun Ceramic-Polymer Composite As A Scaffold for Tissue Repair - The present invention relates to compositions and methods of preparing a three-dimensional matrix of micron sized electrospun fibers, wherein the electrospun fibers are formed from a electrospun composite comprising a bioactive ceramic component and a polymer component. The matrix provides an osteoconductive and osteoinductive scaffold supporting osteogenesis and thereby facilitates bone repair. | 12-08-2011 |