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Ardenkjaer-Larsen

Jan Ardenkjaer-Larsen, Frederiksberg C DK

Patent application numberDescriptionPublished
20080229928SORPTION PUMP WITH INTEGRATED THERMAL SWITCH - A sorption pumping system includes a conductive inner vessel having a sorbent material therein to adsorb gas molecules. An outer vessel is positioned about the inner vessel and includes a heat transfer flange connected thereto. A gas chamber is formed between the inner vessel and the outer vessel. The gas chamber is constructed to sealably contain a thermally conductive gas therein.09-25-2008
20080240998FLUID PATH SYSTEM FOR DISSOLUTION AND TRANSPORT OF A HYPERPOLARIZED MATERIAL - A fluid path system includes a vial containing a frozen pharmaceutical product therein. A dissolution fluid path is also included in the fluid path system, the dissolution fluid path having an output end in fluid communication with the vial and an input end attached to a pressure vessel containing a dissolution medium. A delivery fluid path is also included in the system having a first end hermetically attached to the vial to transport therefrom a mixture of dissolved pharmaceutical product and dissolution medium and a second end connected to a receiving vessel to receive the mixture. A dissolution fluid path valve is positioned between the pressure vessel and the dissolution fluid path to control flow of the dissolution medium, and a delivery fluid path valve is also included in the fluid path system to control flow of the mixture from the delivery fluid path to the receiving vessel.10-02-2008
20080242974METHOD AND APPARATUS TO HYPERPOLARIZE MATERIALS FOR ENHANCED MR TECHNIQUES - A system for polarizing a material to be used in techniques employing magnetic resonance (MR) is provided. The polarizer system includes a cooling chamber having a cryogenic refrigerant therein for use in polarizing a substance. A sorption pump is connected to the cooling chamber to reduce a pressure therein to allow for hyperpolarizing of the sample. The sorption pump is cooled by a refrigeration system to promote molecular adsorption in the sorption pump. The cooling chamber, sorption pump, and refrigeration system are arranged in a closed system.10-02-2008

Jan Henrik Ardenkjaer-Larsen, Amersham GB

Jan Henrik Ardenkjaer-Larsen, Frederiksberg DK

Patent application numberDescriptionPublished
20080275659APPARATUS AND METHOD FOR FULLY AUTOMATED CLOSED SYSTEM QUALITY CONTROL OF A SUBSTANCE - The present invention provides an apparatus and method for automated quality control of a substance comprising a compartment wherein a substance is located, a monitoring device coupled to the compartment and configured to monitor at least one quality control parameter prior to an end-use of the substance, and a processor coupled to the monitoring device, wherein the monitoring device is configured to communicate data to the processor for comparing at least one quality control parameter to an end-use value, and wherein the processor is further configured to control the release of the substance from the compartment to its end-use.11-06-2008

Jan-Henrik Ardenkjaer-Larsen, Buckinghamshire GB

Patent application numberDescriptionPublished
20090162287Method of Cardiac Imaging - The invention relates to a method of cardiac imaging using hyperpolarised 06-25-2009

Jan-Henrik Ardenkjaer-Larsen, Frederiksberg C DK

Patent application numberDescriptionPublished
20110270073ELECTRON SPIN RESONANCE IMAGING SCANNER - An electron paramagnetic resonance imaging (EPRI) system includes a resistive magnet driven by a power supply such as a power supply module to generate radio frequency signals in a substantially coherent polyphase perfect sequence scheme. The EPRI system further includes image acquisition and processing electronics configured to generate, acquire, quantify and map pO2 information associated with a free radical agent in vivo and having a resonance line width that is sensitive to oxygen and in response to the radio frequency signals without imparting harmful heating effects to a corresponding human or animal body.11-03-2011