Ardenkjaer-Larsen
Jan Ardenkjaer-Larsen, Frederiksberg C DK
Patent application number | Description | Published |
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20080229928 | SORPTION PUMP WITH INTEGRATED THERMAL SWITCH - A sorption pumping system includes a conductive inner vessel having a sorbent material therein to adsorb gas molecules. An outer vessel is positioned about the inner vessel and includes a heat transfer flange connected thereto. A gas chamber is formed between the inner vessel and the outer vessel. The gas chamber is constructed to sealably contain a thermally conductive gas therein. | 09-25-2008 |
20080240998 | FLUID PATH SYSTEM FOR DISSOLUTION AND TRANSPORT OF A HYPERPOLARIZED MATERIAL - A fluid path system includes a vial containing a frozen pharmaceutical product therein. A dissolution fluid path is also included in the fluid path system, the dissolution fluid path having an output end in fluid communication with the vial and an input end attached to a pressure vessel containing a dissolution medium. A delivery fluid path is also included in the system having a first end hermetically attached to the vial to transport therefrom a mixture of dissolved pharmaceutical product and dissolution medium and a second end connected to a receiving vessel to receive the mixture. A dissolution fluid path valve is positioned between the pressure vessel and the dissolution fluid path to control flow of the dissolution medium, and a delivery fluid path valve is also included in the fluid path system to control flow of the mixture from the delivery fluid path to the receiving vessel. | 10-02-2008 |
20080242974 | METHOD AND APPARATUS TO HYPERPOLARIZE MATERIALS FOR ENHANCED MR TECHNIQUES - A system for polarizing a material to be used in techniques employing magnetic resonance (MR) is provided. The polarizer system includes a cooling chamber having a cryogenic refrigerant therein for use in polarizing a substance. A sorption pump is connected to the cooling chamber to reduce a pressure therein to allow for hyperpolarizing of the sample. The sorption pump is cooled by a refrigeration system to promote molecular adsorption in the sorption pump. The cooling chamber, sorption pump, and refrigeration system are arranged in a closed system. | 10-02-2008 |
Jan Henrik Ardenkjaer-Larsen, Amersham GB
Jan Henrik Ardenkjaer-Larsen, Frederiksberg DK
Patent application number | Description | Published |
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20080275659 | APPARATUS AND METHOD FOR FULLY AUTOMATED CLOSED SYSTEM QUALITY CONTROL OF A SUBSTANCE - The present invention provides an apparatus and method for automated quality control of a substance comprising a compartment wherein a substance is located, a monitoring device coupled to the compartment and configured to monitor at least one quality control parameter prior to an end-use of the substance, and a processor coupled to the monitoring device, wherein the monitoring device is configured to communicate data to the processor for comparing at least one quality control parameter to an end-use value, and wherein the processor is further configured to control the release of the substance from the compartment to its end-use. | 11-06-2008 |
20140123681 | METHOD AND APPARATUS TO HYPERPOLARIZE MATERIALS FOR ENHANCED MR TECHNIQUES - An apparatus, system, and method for producing hyperpolarized samples for use in magnetic resonance systems. A sorption pump is incorporated into the apparatus to create a closed system for hyperpolarizing. Being a closed system, the apparatus and system loses no cryogen to atmosphere such that there is no need to replenish cryogen in the system. Under the method, the apparatus is able to operate in three distinct modes. | 05-08-2014 |
Jan-Henrik Ardenkjaer-Larsen, Buckinghamshire GB
Patent application number | Description | Published |
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20090162287 | Method of Cardiac Imaging - The invention relates to a method of cardiac imaging using hyperpolarised | 06-25-2009 |
Jan-Henrik Ardenkjaer-Larsen, Frederiksberg C DK
Patent application number | Description | Published |
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20110270073 | ELECTRON SPIN RESONANCE IMAGING SCANNER - An electron paramagnetic resonance imaging (EPRI) system includes a resistive magnet driven by a power supply such as a power supply module to generate radio frequency signals in a substantially coherent polyphase perfect sequence scheme. The EPRI system further includes image acquisition and processing electronics configured to generate, acquire, quantify and map pO2 information associated with a free radical agent in vivo and having a resonance line width that is sensitive to oxygen and in response to the radio frequency signals without imparting harmful heating effects to a corresponding human or animal body. | 11-03-2011 |
20120117985 | FLUID PATH SYSTEM FOR DISSOLUTION AND TRANSPORT OF A HYPERPOLARIZED MATERIAL - A fluid path system includes a vial containing a pharmaceutical product therein. A dissolution fluid path is also included in the fluid path system, the dissolution fluid path having an output end in fluid communication with the vial and an input end attached to a pressure vessel containing a dissolution medium. A delivery fluid path is also included in the system having a first end hermetically attached to the vial to transport therefrom a mixture of dissolved pharmaceutical product and dissolution medium and a second end connected to a receiving vessel to receive the mixture. A dissolution fluid path valve is positioned between the pressure vessel and the dissolution fluid path to control flow of the dissolution medium, and a delivery fluid path valve is also included in the fluid path system to control flow of the mixture from the delivery fluid path to the receiving vessel. | 05-17-2012 |