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Aravind Srinivasan

Aravind Srinivasan, Cambridge, MA US

Patent application numberDescriptionPublished
20080241918Hemagglutinin polypeptides, and reagents and methods relating thereto - The present invention provides a system for analyzing interactions between glycans and interaction partners that bind to them. The present invention also provides HA polypeptides that bind to umbrella-topology glycans, and reagents and methods relating thereto.10-02-2008
20090081193HEMAGGLUTININ POLYPEPTIDES, AND REAGENTS AND METHODS RELATING THERETO - The present invention provides a system for analyzing interactions between glycans and interaction partners that bind to them. The present invention also provides HA polypeptides that bind to umbrella-topology glycans, and reagents and methods relating thereto.03-26-2009
20090269342Hemagglutinin Polypeptides, and Reagents and Methods Relating Thereto - The present invention provides a system for analyzing interactions between glycans and interaction partners that bind to them. The present invention also provides HA polypeptides that bind to umbrella-topology glycans, and reagents and methods relating thereto.10-29-2009
20100004195Decoy Influenza Therapies - The present invention provides umbrella-topology glycan decoys. The present invention provides systems and methods treating influenza infection utilizing inventive umbrella-topology glycan decoys. The present invention provides methods for identifying novel umbrella-topology glycan decoys.01-07-2010
20100061990Hemagglutinin Polypeptides, and Reagents and Methods Relating Thereto - The present invention provides a system for analyzing interactions between glycans and interaction partners that bind to them. The present invention also provides HA polypeptides that bind to umbrella-topology glycans, and reagents and methods relating thereto.03-11-2010
20100136599METHODS AND PRODUCTS RELATED TO THE IMPROVED ANALYSIS OF CARBOHYDRATES - The invention relates, in part, to the improved analysis of carbohydrates. In particular, the invention relates to the analysis of carbohydrates, such as N-glycans and O-glycans found on proteins. Improved methods, therefore, for the study of glycosylation patterns on cells, tissue and body fluids are also provided. Information regarding the analysis of glycans, such as the glycosylation patterns on cells, tissues and in body fluids, can be used in diagnostic and treatment methods as well as for facilitating the study of the effects of glycosylation/altered glycosylation on protein function. Such methods are also provided. Methods are also provided to assess protein production processes, to assess the purity of proteins produced, and to select proteins with the desired glycosylation.06-03-2010
20100144553METHODS AND PRODUCTS RELATED TO THE IMPROVED ANALYSIS OF CARBOHYDRATES - The invention relates, in part, to the improved analysis of carbohydrates. In particular, the invention relates to the analysis of carbohydrates, such as N-glycans and O-glycans found on proteins and saccharides attached to lipids. Improved methods, therefore, for the study of glycosylation patterns on cells, tissue and body fluids are also provided. Information from the analysis of glycans, such as the glycosylation patterns on cells, tissues and in body fluids, can be used in diagnostic and treatment methods as well as for facilitating the study of the effects of glycosylation/altered glycosylation. Such methods are also provided. Methods are further provided to assess production processes, to assess the purity of samples containing glycoconjugates, and to select glycoconjugates with the desired glycosylation.06-10-2010

Patent applications by Aravind Srinivasan, Cambridge, MA US

Aravind Srinivasan, Raleigh, NC US

Patent application numberDescriptionPublished
20080222607Extending Portability of Java Code Through the Use of AOP - A computer-implementable method, system and computer-usable medium for extending the portability of code to a limited-class environment are disclosed. In a preferred embodiment, the method includes the steps of: identifying any full-version-only objects that are not in a reduced-version of a language, wherein the reduced-version of the language comprises a reduced portion of objects that are in a full-version of the language; associating a full-version-only object with a set of one or more objects in the reduced-version of the language, wherein the full-version-only object is functionally equivalent to the set of one or more objects in the reduced-version of the language; identifying any full-version-only objects in a software program; and creating a reduced-version of the software program by replacing any identified full-version-only objects with a functionally equivalent set of one or more objects from the reduced-version of the language.09-11-2008
20090164485TECHNIQUE FOR FINDING REST RESOURCES USING AN N-ARY TREE STRUCTURE NAVIGATED USING A COLLISION FREE PROGRESSIVE HASH - The present invention discloses a data structure which, given an identifier for a Representational State Transfer (REST) resource, can rapidly yield a configured target and simultaneously yield all configured pattern based rules and constraints for the target. The disclosed data structure is a tree structure including nodes for URL portions. Each node is associated with a hash tree specifically grown in a manner that ensures collision occurrences are non-existent. The tree structure is effectively two or more superimposed trees; one for URL pattern matching to determine a target, another for determining constraints. A single tree traversal, which can be based on a progressive hash, can be used to concurrently determine a target and a set of constraints, which represents improved performance over conventional implementations that require multiple, distinct query/response operations to produce equivalent results.06-25-2009

Patent applications by Aravind Srinivasan, Raleigh, NC US