Appelbaum, US
Daniel Appelbaum, Chicago, IL US
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20080298657 | Computer-Aided Method for Detection of Interval Changes in Successive Whole-Body Bone Scans and Related Computer Program Program Product and System - A method of producing an image to aid detection of a change in progress of a disease in a patient is described. In the method, a first image of a distribution of a radioisotope in the patient is obtained. A second image of the distribution of the radioisotope in the patient is also obtained. At least one of the first and second images are then normalized (1:140). One of the images is warped to match the other image using a multiple-segment matching method (1:160). The first image is subtracted from the second image to form a subtraction image (1:220). Finally, the resulting subtraction image is displayed. | 12-04-2008 |
20140004044 | USE OF FLUORINATED DERIVATIVES OF 4-AMINOPYRIDINE IN THERAPEUTICS AND MEDICAL IMAGING | 01-02-2014 |
20140369932 | USE OF FLUORINATED DERIVATIVES OF 4-AMINOPYRIDINE IN THERAPEUTICS AND MEDICAL IMAGING - The present disclosure provides novel compounds, including compounds that bind to potassium channels, methods for their manufacture, and methods for their use, including their use to diagnose and/or assess traumatic brain injury and use to treat dymeylinating diseases, and/or in vivo imaging of the central nervous system, and to diagnose and/or assess the progression of MS or other diseases. | 12-18-2014 |
Edward Appelbaum, Radnor, PA US
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20100028904 | WAY TO OBTAIN HIGH EXPRESSION CLONES OF MAMMALIAN CELLS USING A METHYLCELLULOSE WITH FLUORESCENT PROTEIN A OR G AND FLUORESCENT SCREENING METHOD - The invention provides a genetic screening method for identifying a transfected cell expressing the polypeptide of interest. The methods allows for high throughput screening of recombinant cells for elevated levels of expression of the polypeptide of interest using methylcellulose comprising fluorescent protein A or G to improve detection and cloning. The invention also provides capture media, formulations and methods of making and using thereof. | 02-04-2010 |
Edward Robert Appelbaum, Blue Bell, PA US
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20090017020 | RECOMBINANT IL-5 ANTAGONISTS USEFUL IN TREATMENT OF IL-5 MEDIATED DISORDERS - Chimeric, humanized and other IL-5 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided. | 01-15-2009 |
20100316634 | RECOMBINANT IL-5 ANTAGONISTS USEFUL IN TREATMENT OF IL-5 MEDIATED DISORDERS - Chimeric, humanized and other IL-5 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided. | 12-16-2010 |
Henry R. Appelbaum, Chicago, IL US
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20120095452 | INTERSTITIAL ENERGY TREATMENT PROBE HOLDERS - An interstitial laser energy treatment apparatus having co-acting movable probe holders which facilitate positioning of a laser probe and thermal probe in different positions relative to a tissue mass such as the tumor to be treated and relative to each other to facilitate treating tissue masses based on the exact position, size and shape of the tissue mass. | 04-19-2012 |
20130331828 | INTERSTITIAL ENERGY TREATMENT PROBE HOLDERS - An interstitial laser energy treatment apparatus having co-acting movable probe holders which facilitate positioning of a laser probe and thermal probe in different positions relative to a tissue mass such as the tumor to be treated and relative to each other to facilitate treating tissue masses based on the exact position, size and shape of the tissue mass. | 12-12-2013 |
Jacob G. Appelbaum, Gainesville, FL US
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20090047272 | Compositions with Modified Nucleases Targeted to Viral Nucleic Acids and Methods of Use for Prevention and Treatment of Viral Diseases - Antiviral compositions comprising a modified nuclease, or a plurality of such modified nucleases having at least one non-natural amino acid residue substituted for a naturally occurring amino acid in a parent nuclease are provided, as are methods of use and kits providing unit dosages of such compositions. | 02-19-2009 |
20130306573 | SYSTEM AND METHOD FOR CLEANING HYROCARBON CONTAMINATED WATER - A system or method for removing undesired organic material or particulates, such as crude oil, from water, cavitate the mixture with air; irradiate the jet sprayed cavitated mixture with an electron beam or an electron beam sustained non-thermal plasma discharge to create ozone and free radicals within air-oil-in-water-emulsion; and filter the water from the irradiated mixture. | 11-21-2013 |
20140355775 | WIRED AND WIRELESS MICROPHONE ARRAYS - An acoustic noise canceling microphone arrangement and processor that uses a principal microphone and other microphones that may be incidentally or deliberately located in the vicinity of the principal microphone in order to derive an audio signal of enhanced signal-to-background noise ratio. In one implementation, the principal and incidental microphones comprise the microphone built into a mobile phone and the microphone built into a Bluetooth headset. | 12-04-2014 |
Jason Appelbaum, Emeryville, CA US
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20150266389 | SMART ENERGY DISTRIBUTION METHODS AND SYSTEMS FOR ELECTRIC VEHICLE CHARGING - A power management system can smartly allocate the available power at a location to support more electric vehicles than would otherwise be possible. Power managers can intelligently allocate that power based on the real-time needs of vehicles. A smart energy distribution system can estimate each vehicle's current charge level and use such information to efficiently provide electric vehicle charging. The system can respond dynamically to vehicle charge levels, current readings, and/or electrical mains readings, allocating more current where it is needed. The charger profiles can include historic charge cycle information, which can be analyzed under a set of heuristics to predict future charging needs. A local electric vehicle charging mesh network can be provided, which transmits data packets among short-range transceivers of multiple power managers. The local electric vehicle charging mesh network can be connected to a remote server via a cellular connection. The power managers and the local electric vehicle charging mesh network can intelligently allocate power to multiple electric vehicles. | 09-24-2015 |
Joel Appelbaum, Gainesville, FL US
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20130185565 | Efficient, High Volume Digital Signature System for Medical and Business Applications - The system relates to a method for collecting signatures from pre-validated signers. In one aspect of the method, a pre-validated signer's signature is affixed to an electronic document in an appropriate location after the pre-validated signer authorizes the use of his or her signature. | 07-18-2013 |
Mel Appelbaum, Morristown, NJ US
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20130312984 | FIRE PREVENTION SYSTEMS AND METHODS - A system or method that has an air distribution system configured to provide nitrogen into a room to reduce an oxygen concentration level within the room below a desired oxygen concentration level such that the atmosphere in the room fails to provide sufficient oxygen to sustain combustion. | 11-28-2013 |
Michael Appelbaum, Washington, DC US
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20110167433 | WORKSPACE SYSTEM AND METHOD FOR MONITORING INFORMATION EVENTS - A system and method for monitoring information events partitions sets of information and processing steps into one or more workspaces. The workspaces include sharable portable specifications for implementing event monitoring by a plurality of users or computer systems. Workspaces may be bindable computing resources to establish controls between the computing resources and the workspaces. | 07-07-2011 |
Michael S. Appelbaum, Arlington, VA US
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20100223629 | Data Event Processing and Application Integration in a Network - A system, method and computer program product for providing data event processing and application integration is provided. The present invention provides a novel application integration and event processing server that creates unified and personalized applications on demand out of existing Web services, communications systems, legacy assets, and databases for several types of applications without invasive programming. The present invention also provides a novel XML-based open markup language that allows real-time composite applications (for execution on the server of the present invention) to be easily created and changed while minimizing low-level coding by using a set of pre-defined templates, thus saving the time and expense typically required to create similar solutions from scratch. | 09-02-2010 |
Murray Appelbaum, Monsey, NY US
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20100138976 | Hidden Sleeve Zipper for Tailored Clothing - The invention comprises a non-outerwear garment having at least one sewn seam on a sleeve of the garment and at least one said sleeve has an upper arm portion, a lower arm portion, and a cuff portion. A zipper extends from at least the upper arm portion through the lower arm portion and comprises a plurality of teeth. The plurality of teeth/coils has an open and a closed configuration, and in an at least partially closed configuration, a respective closed portion of the zipper or a fully closed zipper is substantially indistinguishable from the at least one seam. | 06-10-2010 |
Paul Appelbaum, Huntington Beach, CA US
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20100065460 | SNAP-LOCK TWIST-OPEN CARD AND BLISTER PACKAGE - A card and blister package for small articles of commerce has a clear plastic blister piece, a card and a retainer piece. The blister piece had an article-receiving cavity and a flange extends along the upper edge of the cavity, and pluralities of upwardly extending locking posts are spaced apart along the flange. The card has openings for receiving therethrough the locking posts and the retainer piece had a plurality of integral downwardly-opening locking caps spaced therealong, whereby when the posts are engaged through the card openings the caps can be snapped into locking engagement with the blister posts so as to secure the card to the blister. Each cap is encircled by an arrangement of perforations, so as to detachably connect the cap to the retainer piece and whereby twisting of the cap will cause it to shear free of the retainer, and rotation through about 90 degrees will cause the caps to unlock from the posts, allowing the package to be opened. | 03-18-2010 |
20110079529 | Trapped card package - A trapped card package includes a paperboard card having a relatively large central rectangular opening, a clear plastic blister piece with a groove extending along its perimeter and a flange, and a lower clear plastic piece has a male element extending along its perimeter, and a flange. The lower piece male element engages the card opening and its flange abuts the underside of the card and the male element projects upward beyond the top surface of the card where it is received by the perimeter groove of the blister piece as the flange of the blister pieces engages the top surface of the card, so as to trap the card and seal the package when adhesive on the engaged element is cured. | 04-07-2011 |