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Antonio Jose
Antonio Jose Borba Ramires Fernandes, Braga PT
| Patent application number | Description | Published |
|---|---|---|
| 20080310732 | Contour Recovery of Occluded Objects in Images - The present invention relates to a method, apparatus and computer program product for providing contour information related to images. An image obtaining unit obtains a set of interrelated images (step | 12-18-2008 |
Antonio Jose Farre Gomis, Barcelona ES
| Patent application number | Description | Published |
|---|---|---|
| 20080200693 | Derivatives of Aryl (or Heteroaryl) Azolylcarbinols (in Particular Cizolirtin Citrate) for the Treatment of Opioid Addiction - The present invention refers to the use of derivatives of aryl (or heteroaryl) azolylcarbinol of general formula (I), and their physiologically acceptable salts, as medicinal products for human and/or animal therapeutics for the treatment of the symptoms of opioid addiction. The preferred compound is cizolirtin citrate. | 08-21-2008 |
Antonio Jose Gordils Wallis, Avenida Felipe Guevara Rojas VE
| Patent application number | Description | Published |
|---|---|---|
| 20100178631 | Maxillary Bone Cutting and Injection System and Method of Using the Same - A bone cutting and injecting device for cutting maxillary bone and injecting a filler through the maxillary bone under a subantral membrane to separate the subantral membrane from the maxillary bone and fill the space formed therebetween. The device includes a hollow tubular element having a diameter sized to be inserted into a pilot hole in the maxillary bone, a piston longitudinally displaceable within the hollow tubular element, and a cutter mounted to the piston and operably disposed adjacent the distal end of the hollow tubular element. A fluid path is defined through the hollow tubular element for guiding the filler, and the cutter is configured to redirect the filler in a transverse or radial direction relative to the longitudinal axis of the tubular element. | 07-15-2010 |
Antonio Jose Gordils Wallis, Mochi Caracas VE
| Patent application number | Description | Published |
|---|---|---|
| 20080243123 | Maxillary Bone Cutting System, Kit, and Method of Using the Same - A device includes a tubular element, and a cutter spring-biased relative to the tubular element. In an unloaded configuration the cutter is displaced relative to the tubular element by a displacement distance, and when the cutter is in a loaded configuration the displacement distance is reduced. A first structure is longitudinally fixed relative to the cutter and rotationally engaged relative to the tubular element. A length of the first structure extends proximally in the unloaded configuration. A second structure is longitudinally displaceable relative to the first structure. In the loaded configuration, a driver engages and rotates both the first and second structures, and thus the tubular element and cutter together. Once the cutter breaks through the bone, the cutter spring-biased into the unloaded configuration, resulting in disengagement of the first structure from the driver to prevent rotation of either the tubular element or the cutter. | 10-02-2008 |
Antonio Jose Rebeiro, Amarante PT
| Patent application number | Description | Published |
|---|---|---|
| 20100143484 | ORAL SUBMICRON PARTICLE DELIVERY SYSTEM FOR PROTEINS AND PROCESS FOR ITS PRODUCTION - The invention provides a novel submicron system for the oral administration of proteins. An effective oral carrier for proteins should shield its content against the gastrointestinal tract proteases and be capable of facilitating the uptake of the protein drug across the gastrointestinal epithelium. The present invention relates to production of gelled particles which comprises a protein drug susceptible to enzymatic degradation by enzymes and acid conditions in the stomach, a polymeric matrix which undergoes precipitation-swelling process, and two-layer-coating materials which are themselves capable of enhancing absorption of said drug across the intestinal mucosal tissues and of inbihiting degradation of said drug by gastric enzymes. Insulin-loaded particles with appropriate submicron size for gastrointestinal absorption were made of natural occurring polymers by emulsification-based method and proved to be gastric pH and protease protective. Effects on glycemia were observed during 14 h after their oral single administration to rats, achieving 42% of pharmacological activity compared to subcutaneous administration. Postprandial rise in blood glucose was suppressed and insulinemia levels increased by a factor of seven. The relative oral bioavailability of insulin calculated over 8 h by comparison with a subcutaneous injection of free insulin was 34%. | 06-10-2010 |
Antonio Jose Sanz Fernández, Madrid ES
| Patent application number | Description | Published |
|---|---|---|
| 20100196878 | DUAL-RECOGNITION IMMUNOASSAY FOR THE DETECTION OF ANTIBODIES - The invention relates to a dual-recognition immunoassay for the detection of antibodies specific to a target antigen in a sample which comprises contacting said target antigen with a sample suspected of containing said antibodies specific to said target antigen under conditions allowing the formation of an antigen-antibody complex; adding a conjugate comprising said target antigen and a marker under conditions allowing the formation of an antigen-antibody-antigen/marker complex; and detecting said antigen-antibody-antigen/marker complex. The immunoassay can be used, among other applications, in the diagnosis of infections caused by pathogenic organisms with high sensitivity and specificity. | 08-05-2010 |
Antonio Jose Sanz Fernández, Madrid ES
| Patent application number | Description | Published |
|---|---|---|
| 20100196878 | DUAL-RECOGNITION IMMUNOASSAY FOR THE DETECTION OF ANTIBODIES - The invention relates to a dual-recognition immunoassay for the detection of antibodies specific to a target antigen in a sample which comprises contacting said target antigen with a sample suspected of containing said antibodies specific to said target antigen under conditions allowing the formation of an antigen-antibody complex; adding a conjugate comprising said target antigen and a marker under conditions allowing the formation of an antigen-antibody-antigen/marker complex; and detecting said antigen-antibody-antigen/marker complex. The immunoassay can be used, among other applications, in the diagnosis of infections caused by pathogenic organisms with high sensitivity and specificity. | 08-05-2010 |
Antonio Jose Silva Valente, Quinta Do Conde PT
| Patent application number | Description | Published |
|---|---|---|
| 20080223796 | Process and Device for Separation of Liquids Emulsified in Mixtures of Liquids and Gases Dissolved in Mixtures of Liquids and Gases by Localized Pressure Reduction - A process and a device implementing the process, for separating fluids in emulsion and/or in solution, and/or for low pressure distillation, in particular of water and/or gaseous hydrocarbons dissolved in crude petroleum, and/or for separation of crude petroleum droplets emulsified in water, to obtain water with necessary characteristics for its injection without pollution of underground aquifers, and/or when the mixture is dominant in crude petroleum, acceleration of settling of the water in the lower part of the mixture, and/or for low pressure distillation of crude petroleum. The method creates a localized zone of reduced pressure on part of the free surface of a liquid to be processed, within a closed processing tank, without the overall pressure inside the closed processing tank being affected. | 09-18-2008 |