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Antonella
Antonella Accardo, Torre Del Greco IT
| Patent application number | Description | Published |
|---|---|---|
| 20090130018 | SUPRAMOLECULAR AGGREGATES CONTAINING CHELATING AGENTS AND BIOACTIVE PEPTIDES AS EFFECTIVE AND SELECTIVE DELIVERY TOOLS FOR DRUGS AND CONTRAST AGENTS IN MRI OR NUCLEAR MEDICINE - The invention relates to supramolecular aggregates obtained by coaggregation of two monomers: —a first monomer containing a paramagnetic or radioactive metal ion complexed by a chelating agent having a lipophilic moiety, —a second monomer containing a bioactive peptide linked to a lipophilic moiety through an organic spacer. The aggregates are selectively driven by the exposed bioactive peptide on a desired biological target. The aggregates (micelles, vesicles or liposomes) could entrap on their inner region or on their surface a pharmaceutical active principle (drug). The invention thus relates to target specific delivery of drugs and/or metal ions. The invention therefore provides compositions containing said aggregates for use as contrast agents, in nuclear medicine or MRI, for the selective delivery of drugs, and for simultaneous delivery of a drug and a metal ion. | 05-21-2009 |
Antonella Antignani, North Bethesda, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100317577 | Methods and Compositions for Inhibiting Cell Death or Enhacing Cell Proliferation - The present invention provides compositions and methods that enhance cell survival. Such compositions feature chimeric polypeptides that include at least a GM-CSF receptor ligand and an anti-apoptotic moiety (e.g., a Bcl-2 protein family member). In one embodiment, the chimeric polypeptide is a GM-CSF-Bcl-xL chimeric polypeptide. The invention further includes methods of using chimeric polypeptides to enhance cell survival or inhibit cell death in a cell at risk of cell death. | 12-16-2010 |
Antonella Caivano, Roma IT
| Patent application number | Description | Published |
|---|---|---|
| 20110014223 | MULTIMERIC PROTEINS ABLE TO INDUCE AN ANTIBODY RESPONSE AGAINST THE BETA-AMYLOID AND USE THEREOF - The present invention relates to the fields of molecular biology, immunology and medicine. Peptide sequences that belong to the beta amyloid peptide are exposed on the surface of a multimeric structure derived from the E2 component of alpha keto acid dehydrogenase. The molecules are useful for the production of vaccines for the treatment and/or prevention of Alzheimer's disease. | 01-20-2011 |
Antonella Chiechi, Matera IT
| Patent application number | Description | Published |
|---|---|---|
| 20120065166 | Bone Modulators And Methods Therewith - THE INVENTION RELATES TO compositions, compounds, proteins and methods of treatment therewith. Aspects of embodiments also relate to a method of treating a patient by delivering to the tissues of said patient or administering to said patient a therapeutically effective amount of one or more compounds. Aspects of embodiments also relate to a method of detecting the presence of bone disease by machine-assaying detectable serotonin. Aspects of embodiments also relate to methods of treating disease in subjects. | 03-15-2012 |
| 20120076770 | Modulation of autophagy and and serotonin for treatment of multiple myeloma related diseases - THE INVENTION RELATES TO compounds, proteins and methods of treatment therewith. Aspects of embodiments of the invention further relates to compounds and methods of treatment for bone, bone marrow, and bone tissue. | 03-29-2012 |
Antonella Ciavolella, Bizzarone (co) IT
| Patent application number | Description | Published |
|---|---|---|
| 20120114641 | THERAPEUTIC COMBINATION COMPRISING A PLK1 INHIBITOR AND AN ANTINEOPLASTIC AGENT - The present invention provides a combination comprising (a) a compound of formula (I) and (b) one or more antineoplastic agents selected from the group consisting of an antimetabolite agent, analkylating or alkylating-like agent, an intercalating agent, a topoisomerase I or II inhibitor, an antimitotic agent, a kinase inhibitor, a proteasome inhibitor and an antibody inhibiting a growth factor or its receptor, wherein active ingredients of the combination are present in each case in free form or in the form of a pharmaceutically acceptable salt or any hydrate or solvate thereof, useful in the treatment of tumors. | 05-10-2012 |
Antonella Colagrande, L'Aquila IT
| Patent application number | Description | Published |
|---|---|---|
| 20100216190 | Novel Selection System - The present invention relates to a method of producing a recombinant protein comprising using a selection method other than antibiotics. In particular, it relates to a stable host/vector system based on the pyrC gene complementation designed to produce high level of heterologous recombinant protein in | 08-26-2010 |
Antonella Commiato, Spring, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100185506 | SYSTEMS AND METHODS USED IN THE OPERATION OF A RECYCLING ENTERPRISE - A system and computer program product for managing an online recycling operation, including uniquely associating one or more recyclable products with unique identifiers and other product information stored in a database, receiving information associated with the one or more recyclable products, periodically storing and updating the information associated with the one or more recyclable products in the database, associating the unique identifier with a recycling user having user account information stored in the database, updating the reward point total based on an activity of the recycling user, communicating the product information and the user account information to the recycling user over a network, communicating rewards that are available in exchange for reward points to the recycling user over the network, and redeeming reward points upon demand by the recycling user over the network. Each recyclable product includes indicia that uniquely identifies the recyclable product. The user account information includes user information comprising a reward point total and recycling data associated with the recycling user. The activity includes recycling activities and active participation on an environmentally-friendly web server. | 07-22-2010 |
Antonella Converso, Elkins Park, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100305135 | AHCY HYDROLASE INHIBITORS FOR TREATMENT OF HYPER HOMOCYSTEINEMIA - The present invention is directed to AHCY inhibitors of formula (I) which are useful in the treatment of diseases characterized by high homocysteine levels, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases characterized by high homocysteine levels. | 12-02-2010 |
| 20110124661 | OXAZOLOBENZIMIDAZOLE DERIVATIVES - The present invention is directed to oxazolobenzimidazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved. | 05-26-2011 |
| 20110160229 | AHCY HYDROLASE INHIBITORS FOR TREATMENT OF HYPER HOMOCYSTEINEMIA - The present invention is directed to AHCY inhibitors of formula (I): which are useful in the treatment of diseases characterized by high homocysteine levels, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases characterized by high homocysteine levels. | 06-30-2011 |
| 20110178117 | OXAZOLOBENZIMIDAZOLE DERIVATIVES - The present invention is directed to oxazolobenzimidazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved. | 07-21-2011 |
Antonella Crisari, Rome IT
| Patent application number | Description | Published |
|---|---|---|
| 20080311577 | Method for the Identification of Sulfo-Oxidizing Bacteria and for the Monitoring of Elemental Sulfur in the Environment - A method is described for the identification of sulfooxidizing bacteria comprising the extraction of the DNA from environmental samples and the subsequent identification of at least one fragment of the Thio 16S gene or SoxB gene present in these bacteria. The method can be used for determining the level of elemental sulfur in samples of soil. | 12-18-2008 |
Antonella Cucchetti, Beverly, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080245957 | TUNING AN ION IMPLANTER FOR OPTIMAL PERFORMANCE - An approach that tunes an ion implanter for optimal performance is described. In one embodiment, there is a system for tuning an ion implanter having multiple beamline elements to generate an ion beam having desired beam properties. In this embodiment, the system comprises a beamline element settings controller configured to provide beamline element settings for generating the desired beam properties. A tuning model correlates the beamline element settings with beam properties. A calibration component is configured to calibrate the tuning model in response to a determination that beam properties measured from using the tuned beamline element settings differs from the determined tuned beamline element settings. | 10-09-2008 |
| 20100084581 | IMPLANT UNIFORMITY CONTROL - An apparatus and method for ion implantation that include destabilizing the ion beam as it passes through magnetic field, preferably a dipole magnetic field is disclosed. By introducing a bias voltage at certain points within the magnetic field, electrons from the plasma are drawn toward the magnet, thereby causing the ion beam to expand due to space charge effects. The bias voltage can be introduced into the magnet in a region where the magnetic field has only one component. Alternatively, the bias voltage can be in a region wherein the magnetic field has two components. | 04-08-2010 |
Antonella Cucchetti, Manchester By The Sea, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120088035 | PLATEN CONTROL - A system and method for maintain a desired degree of platen flatness is disclosed. A laser system is used to measure the flatness of a platen. The temperature of the platen is then varied to achieve the desired level of flatness. In some embodiments, this laser system is only used during a set up period and the resulting desired temperature is then used during normal operation. In other embodiments, a laser system is used to measure the flatness of the platen, even while the workpiece is being processed. | 04-12-2012 |
Antonella Curulli, Roma IT
| Patent application number | Description | Published |
|---|---|---|
| 20080258116 | Titanium Oxide Based Hybrid Material, Respective Preparation Process and Uses - Titanium oxide based hybrid material usable as an electrochemical sensor which is particularly sensitive for detecting chemical and biological substances, in particular substances which act as neurotransmitters. Said material may be represented by the formula: TiCxOyHz with 0.1≦x≦0.6, 2.0≦y≦3.0 and 0.1≦z≦0.9 and may be produced and deposited on a substrate using two techniques called: Polymeric precursor route and MOCVD (Metalorganic Chemical Vapour Deposition). | 10-23-2008 |
Antonella Demico, Roma IT
| Patent application number | Description | Published |
|---|---|---|
| 20100227919 | Dioxaspiroketal Derivatives, Process for Their Preparation and Uses Thereof - The invention relates to dioxaspiroketal derivatives of formula (I): wherein R, is selected from the group consisting of H, straight or branched chain C | 09-09-2010 |
Antonella Di Meo, Caronno Pertusella IT
| Patent application number | Description | Published |
|---|---|---|
| 20100240930 | Process for the manufacture of polyol perfluoropolyether derivative - A process for the manufacture of a polyol (per)fluoropolyether derivative, comprising: 1. reacting at least one triol having two protected hydroxyl functions and a free hydroxyl group with an activating agent, to yield an activated protected triol; 2. reacting the activated protected triol with a functional (per)fluoropolyether derivative of formula: T | 09-23-2010 |
Antonella Di Meo, Caronno Pertusella (varese) IT
| Patent application number | Description | Published |
|---|---|---|
| 20090209442 | CYCLIC PHOSPHAZENE COMPOUND - A cyclic phosphazene compound complying with formula (I) or (II): | 08-20-2009 |
Antonella Ermoli, Buccinasco IT
| Patent application number | Description | Published |
|---|---|---|
| 20090099221 | PYRIDYL-AND PYRIMIDINYL-SUBSTITUTED PYRROLE-, THIOPHENE-AND FURANE-DERIVATIVES AS KINASE INHIBITORS - The present invention provides compounds of the formula (I), or the pharmaceutically acceptable salts thereof, wherein G, W, R | 04-16-2009 |
Antonella Flaibani, Udine IT
| Patent application number | Description | Published |
|---|---|---|
| 20080200428 | Antiproliferative Drug - Object of the present invention are esterified conjugates of hyaluronic acid having anti-proliferative activity. | 08-21-2008 |
Antonella Folgori, Fregene-Rome IT
| Patent application number | Description | Published |
|---|---|---|
| 20090035277 | Hepatitis C Virus Nucleic Acid Vaccine - The present invention features nucleic acid constructs that can be used as a HCV nucleic acid vaccine, vaccine component, or in the production of a HCV vaccine. Described constructs include those: (1) encoding for a chimeric HCV polypeptide containing a NS3-4A region based on a first HCV strain and an NS3-NS4A-NS4B-NS5A or an NS3-NS4A-NS4B-NS5A-NS5B region based on a second strain; and (2) a chimpanzee based adenovector encoding an HCV polypeptide. | 02-05-2009 |
Antonella Isacchi, Milan IT
| Patent application number | Description | Published |
|---|---|---|
| 20100022532 | USE OF A KINASE INHIBITOR FOR THE TREATMENT OF PARTICULAR RESISTANT TUMORS - The invention provides low molecular weight compounds, namely 1H-thieno[2,3-c]pyrazoles, showing a high affinity for the ATP pocket of ABL tyrosine kinase. These compounds are thus ATP-competitive tyrosine kinase inhibitors displaying a significant inhibitory potency also, and in particular, towards BCR-ABL inhibitor-resistant T315I ABL mutants. The compounds of the invention find a useful application in the treatment of BCR-ABL inhibitor-resistant ABL-mediated diseases, such as Imatinib-resistant chronic myelogenous leukemia. Moreover, the invention provides a screening method for the identification of compounds capable of binding the ATP pocket of a kinase protein, in particular of the T315I mutant ABL kinase. | 01-28-2010 |
| 20100035876 | Use of a Kinase Inhibitor for the Treatment of Particular Resistant Tumors - The invention provides low molecular weight compounds, namely tetrahydropyrrolo[3,4-c]pyrazoles, showing a high affinity for the ATP pocket of ABL tyrosine kinase. These compounds are thus ATP-competitive tyrosine kinase inhibitors displaying a significant inhibitory potency also, and in particular, towards BCR-ABL inhibitor-resistant T315I ABL mutants. The compounds of the invention find a useful application in the treatment of BCR-ABL inhibitor-resistant ABL-mediated diseases, such as Imatinib-resistant chronic myelogenous leukemia. Moreover, the invention provides a screening method for the identification of compounds capable of binding the ATP pocket of a kinase protein, in particular of the T315I mutant ABL kinase. | 02-11-2010 |
Antonella Malcangi, Rodano IT
| Patent application number | Description | Published |
|---|---|---|
| 20100047873 | PROCESS FOR THE PRODUCTION OF DAPTOMYCIN - The present invention relates to an improved process for the production of Daptomycin by fermentation with | 02-25-2010 |
Antonella Milella, Bari IT
| Patent application number | Description | Published |
|---|---|---|
| 20110217628 | CATALYST THIN LAYER AND METHOD FOR FABRICATING THE SAME - The catalyst thin layer consists of electronically conductive catalyst nano-particles embedded in a polymeric matrix. The ratio number of catalyst atoms/total number of atoms in the catalyst layer is comprised between 40% and 90%, more preferably between 50% and 60%. | 09-08-2011 |
Antonella Pavese, Norristown, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100185651 | RETRIEVING AND DISPLAYING INFORMATION FROM AN UNSTRUCTURED ELECTRONIC DOCUMENT COLLECTION - Methods, systems, and apparatus, including computer programs stored on computer storage media, for retrieval and display of information from an unstructured electronic document collection. One aspect can be embodied in machine-implemented methods that include the actions of receiving a machine-readable search query from a user and responding to the search query with instructions for presenting the user with a structured presentation of instances relevant to the search query. A visual presentation of the structured presentation denotes associations between the instances and values that characterize attributes of the instances by virtue of an arrangement of identifiers of the instances and the values. | 07-22-2010 |
| 20100185666 | ACCESSING A SEARCH INTERFACE IN A STRUCTURED PRESENTATION - Methods, systems, and apparatus, including computer programs stored on computer storage media, for accessing a search interface from a structured presentation. One aspect can be embodied in machine-implemented methods that include the actions of displaying a structured presentation on a display device, receiving data characterizing a user interaction with the displayed structured presentation, the data including a specification of a first instance and a first attribute of the structured presentation, and displaying a formerly concealed search interface on the display device in response to receiving the data. | 07-22-2010 |
Antonella Pittiglio, Savigny Sur Orge FR
| Patent application number | Description | Published |
|---|---|---|
| 20090267333 | Air-bag and a method of controlling pressure within an air-bag - An air-bag ( | 10-29-2009 |
Antonella Stravato, Philadelphia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090305031 | NANODIAMOND MANUFACTURE AND PROCESS FOR MAKING THEREOF - Disclosed are novel coatings and other components of articles of manufacture featuring the inclusion of nanodiamonds therein. Also disclosed are methods of achieving such inclusion and methods of utilizing the resultant, improved articles. | 12-10-2009 |
Antonella Tajani, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20080203397 | Switching Device - A high voltage diamond based switching device capable of sustaining high currents in the on state with a relatively low impedance and a relatively low optical switching flux, and capable of being switched off in the presence of the high voltage being switched. The device includes a diamond body having a Schottky barrier contact, held in reverse bias by the applied voltage to be switched, to an essentially intrinsic diamond layer or portion in the diamond body, a second metal contact, and an optical source or other illuminating or irradiating device such that when the depletion region formed by the Schottky contact to the intrinsic diamond layer is exposed to its radiation charge carriers are generated. Cain in the total number of charge carriers then occurs as a result of these charge carriers accelerating under the field within the intrinsic diamond layer and generating further carriers by assisted avalanche breakdown. | 08-28-2008 |
Antonella Torosantucci, Rome IT
| Patent application number | Description | Published |
|---|---|---|
| 20090214566 | Protective anti-glucan antibodies with preference for beta-1,3- glucans - Anti-β-1,3-glucan antibodies have been found to be protective against systemic fungal infection with | 08-27-2009 |
| 20100297130 | PROTECTIVE ANTI-GLUCAN ANTIBODIES WITH PREFERENCE FOR BETA-1,3-GLUCANS - Anti-β-1,3-glucan antibodies have been found to be protective against systemic fungal infection with | 11-25-2010 |
| 20120107316 | PROTECTIVE ANTI-GLUCAN ANTIBODIES WITH PREFERENCE FOR BETA-1,3-GLUCANS - Anti-β-1,3-glucan antibodies have been found to be protective against systemic fungal infection with | 05-03-2012 |
Antonella Ursini, Verona IT
| Patent application number | Description | Published |
|---|---|---|
| 20080249108 | Chemical Compounds - The invention relates to methods for the treatment of medical conditions comprising administering an effective amount of a compound of formula (I): | 10-09-2008 |