Patent application number | Description | Published |
20090318564 | Process for preparing and drying solid rasagiline base - Disclosed is crystalline R(+)-N-propargyl-l-aminoindan containing water at an amount of less than 0.5% by weight and a pharmaceutical composition comprising the same, and the process for the manufacture and the validation thereof. Also disclosed is a process for the preparation of solid rasagiline base. | 12-24-2009 |
20100010095 | Process for purifying rasagiline base - Disclosed is crystalline R(+)-N-propargyl-1-aminoindan and racemic N-propargyl-1-aminoindan characterized by colorless crystals a pharmaceutical composition comprising the same, and the process for the manufacture and the validation thereof. Also disclosed is pure liquid R(+)-N-propargyl-1-aminoindan and a pharmaceutical composition comprising the same, and the process for the manufacture thereof. | 01-14-2010 |
20100144887 | Crystalline solid rasagiline base - The subject invention provides crystalline R(+)-N-propargyl-1-aminoindan, pharmaceutical compositions and methods of manufacture thereof. | 06-10-2010 |
20100145101 | Crystalline solid rasagiline base - The subject invention provides crystalline R(+)-N-propargyl-1-aminoindan, pharmaceutical compositions and methods of manufacture thereof. | 06-10-2010 |
20100189787 | Delayed release rasagiline citrate formulation - Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties. | 07-29-2010 |
20100189788 | Delayed release rasagiline base formulation - Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties. | 07-29-2010 |
20100189790 | Delayed release rasagiline formulation - Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties. | 07-29-2010 |
20100189791 | Delayed release rasagiline malate formulation - Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties. | 07-29-2010 |
20100190859 | Citrate Salt of Rasagiline - The subject invention provides rasagiline citrate, its compositions and processes for the manufacture thereof. | 07-29-2010 |
20110112141 | CRYSTALS OF LAQUINIMOD SODIUM, AND PROCESS FOR THE MANUFACTURE THEREOF - Disclosed is a process for the preparation of laguinimod sodium which removes the impurities after the salt formation step, thus resulting in crystals of higher purity as well as crystals having improved crystalline characteristics. | 05-12-2011 |
20110118308 | CRYSTALS OF LAQUINIMOD SODIUM, AND PROCESS FOR THE MANUFACTURE THEREOF - Disclosed is a process for the preparation of laquinimod sodium which removes the impurities after the salt formation step, thus resulting in crystals of higher purity as well as crystals having improved crystalline characteristics. | 05-19-2011 |
20110152381 | 3-KETO-N-PROPARGYL-1-AMINOINDAN - The subject invention provides a pharmaceutical composition containing N-propargyl-1(R)-aminoindan or a pharmaceutically acceptable salt thereof, and a compound of 3-keto-N-propargyl-1-aminoindan or a salt thereof. | 06-23-2011 |
20110281953 | PROCESS FOR PREPARING AND DRYING SOLID RASAGILINE BASE - Disclosed is crystalline R(+)-N-propargyl-1-aminoindan containing water at an amount of less than 0.5% by weight and a pharmaceutical composition comprising the same, and the process for the manufacture and the validation thereof. Also disclosed is a process for the preparation of solid rasagiline base. | 11-17-2011 |
20120003310 | DELAYED RELEASE RASAGILINE FORMULATION - Disclosed are formulations of rasagiline base which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties. Also, disclosed are rasagiline citrate salt and the use and process of manufacture thereof. | 01-05-2012 |
20120100189 | DELAYED RELEASE RASAGILINE MALATE FORMULATION - Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties. | 04-26-2012 |
20120101168 | DEUTERIUM ENRICHED RASAGILINE - The subject invention provides deuterated rasagiline, its salts and uses. | 04-26-2012 |
20120263789 | DELAYED RELEASE RASAGILINE FORMULATION - Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties. | 10-18-2012 |
20130089610 | R(+)-N-METHYL-PROPARGYL-AMINOINDAN - The subject invention provides R(+)-N-methyl-propargyl-aminoindan or a pharmaceutically acceptable salt thereof and a composition containing R(+)-N-propargyl-1(R)-aminoindan or a pharmaceutically acceptable salt thereof, and a compound of R(+)-N-methyl-propargyl-aminoindan or a salt thereof. | 04-11-2013 |
20130089611 | RASAGILINE CITRAMIDE - The subject invention provides rasagiline citramide and a composition containing N-propargyl-1(R)-aminoindan or a pharmaceutically acceptable salt thereof, and a compound of rasagiline citramide or a salt thereof. | 04-11-2013 |
20130089612 | R(+)-N-FORMYL-PROPARGYL-AMINOINDAN - The subject invention provides R(+)-N-formyl-propargyl-aminoindan and a composition containing N-propargyl-1(R)-aminoindan or a pharmaceutically acceptable salt thereof, and a compound of R(+)-N-formyl-propargyl-aminoindan. | 04-11-2013 |
20140128430 | AMINE SALTS OF LAQUINIMOD - The subject invention provides a Laquinimod amine salt, which is laquinimod meglumine, laquinimod choline hydroxide, laquinimod L-lysine or laquinimod monoethanolamine. | 05-08-2014 |
20140171647 | CRYSTALS OF LAQUINIMOD SODIUM, AND PROCESS FOR THE MANUFACTURE THEREOF - Disclosed is a process for the preparation of laquinimod sodium which removes the impurities after the salt formation step, thus resulting in crystals of higher purity as well as crystals having improved crystalline characteristics. | 06-19-2014 |
20140186514 | DELAYED RELEASE RASAGILINE FORMULATION - Disclosed are formulations which are designed to delay release of rasagiline while maintaining specific pharmacokinetic properties. | 07-03-2014 |
20140271878 | CRYSTALS OF LAQUINIMOD SODIUM AND IMPROVED PROCESS FOR THE MANUFACTURE THEREOF - The subject invention provides a mixture of crystalline laquinimod sodium particles, wherein (i) 90% or more of the total amount by volume of the laquinimod sodium particles have a size of 40 microns or less or (ii) 50% or more of the total amount by volume of the laquinimod sodium particles have a size of 15 microns or less, and wherein:
| 09-18-2014 |
20140364506 | DEUTERIUM ENRICHED RASAGILINE - The subject invention provides deuterated rasagiline, its salts and uses. | 12-11-2014 |
20150038744 | Crystalline Solid Rasagiline Base - The subject invention provides crystalline R(+)-N-propargyl-1-aminoindan, pharmaceutical compositions and methods of manufacture thereof. | 02-05-2015 |
20150045445 | 3-KETO-N-PROPARGYL-1-AMINOINDAN - The subject invention provides a pharmaceutical composition containing N-propargyl-1(R)-aminoindan or a pharmaceutically acceptable salt thereof, and a compound of 3-keto-N-propargyl-1-aminoindan or a salt thereof. | 02-12-2015 |