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Annis, US

David Allen Annis, Cambridge, MA US

Patent application numberDescriptionPublished
20090275519Therapeutic peptidomimetic macrocycles - The present invention provides biologically active peptidomimetic macrocycles for the treatment of cell proliferative disorders such as cancer and immunoproliferative disease.11-05-2009
20100216688PEPTIDOMIMETIC MACROCYCLES - The present invention provides biologically active crosslinked polypeptides with improved properties relative to their corresponding precursor polypeptides, having good cell penetration properties and reduced binding to human proteins. The invention additionally provides methods of identifying and making such improved polypeptides.08-26-2010
20100298201PEPTIDOMIMETIC MACROCYCLES WITH IMPROVED PROPERTIES - The present invention provides biologically active peptidomimetic macrocycles with improved properties relative to their corresponding polypeptides. The invention additionally provides methods of preparing and using such macrocycles, for example in therapeutic applications.11-25-2010
20110223149PEPTIDOMIMETIC MACROCYCLES - The present invention provides biologically active peptidomimetic macrocycles with improved properties, such as protease resistance, relative to their corresponding polypeptides. The invention additionally provides methods of preparing and using such macrocycles, for example in therapeutic applications.09-15-2011
20120040889PEPTIDOMIMETIC MACROCYCLES - The present invention provides novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of viral disease.02-16-2012
20120149648THERAPEUTIC PEPTIDOMIMETIC MACROCYCLES - The present invention provides biologically active peptidomimetic macrocycles for the treatment of cell proliferative disorders such as cancer and immunoproliferative disease.06-14-2012
20120172311PEPTIDOMIMETIC MACROCYCLES - The present invention provides biologically active crosslinked polypeptides with improved properties relative to their corresponding precursor polypeptides, having good cell penetration properties and reduced binding to human proteins. The invention additionally provides methods of identifying and making such improved polypeptides.07-05-2012

Patent applications by David Allen Annis, Cambridge, MA US

David H. Annis, Charlotte, NC US

Patent application numberDescriptionPublished
20100129780ATHLETIC PERFORMANCE RATING SYSTEM - In one embodiment, the present invention is directed to an athleticism rating method for normalizing and more accurately comparing overall athletic performance of at least two athletes. Each athlete completes at least two different athletic performance tests. Each test is designed to measure a different athletic skill that is needed to compete effectively in a defined sport. The results from each test for a given athlete are normalized by comparing the test results to a database providing the distribution of test results among a similar class of athletes and then assigning each test result a point number based on that test result's percentile among the distribution of test results. Combining the point numbers derived from the at least two different athletic performance tests for an athlete produces an athleticism rating score representing the overall athleticism of each athlete.05-27-2010
20120130514ATHLETIC PERFORMANCE RATING SYSTEM - In one embodiment, the present invention is directed to an athleticism rating method for normalizing and more accurately comparing overall athletic performance of at least two athletes. Each athlete completes at least two different athletic performance tests. Each test is designed to measure a different athletic skill that is needed to compete effectively in a defined sport. The results from each test for a given athlete are normalized by comparing the test results to a database providing the distribution of test results among a similar class of athletes and then assigning each test result a point number based on that test result's percentile among the distribution of test results. Combining the point numbers derived from the at least two different athletic performance tests for an athlete produces an athleticism rating score representing the overall athleticism of each athlete.05-24-2012
20120130515ATHLETIC PERFORMANCE RATING SYSTEM - In one embodiment, the present invention is directed to an athleticism rating method for normalizing and more accurately comparing overall athletic performance of at least two athletes. Each athlete completes at least two different athletic performance tests. Each test is designed to measure a different athletic skill that is needed to compete effectively in a defined sport. The results from each test for a given athlete are normalized by comparing the test results to a database providing the distribution of test results among a similar class of athletes and then assigning each test result a point number based on that test result's percentile among the distribution of test results. Combining the point numbers derived from the at least two different athletic performance tests for an athlete produces an athleticism rating score representing the overall athleticism of each athlete.05-24-2012

Gary David Annis, Landenberg, PA US

Patent application numberDescriptionPublished
20090036686PREPARATION AND USE OF 2-SUBSTITUTED-5-OXO-3-PYRAZOLIDINECARBOXYLATES - A method is disclosed for preparing a 2-substituted-5-oxo-3-pyrazolidinecarboxylate compound of Formula I02-05-2009
20090054647Method for Preparing Substituted Pyrimidines - Disclosed a method for preparing a compound of Formula 1,02-26-2009
20100029950NOVEL SUBSTITUTED 1H-DIHYDROPYRAZOLES, THEIR PREPARATION AND USE - This invention provides compounds of Formula I, methods for their preparation and use for preparing compounds of Formula II02-04-2010
20100063287PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES - Disclosed is a method for preparing a compound of Formula 1 comprising (1) contacting a compound of Formula 2, with (2) at least one alkali metal cyanide and (3) at least one compound of Formula 403-11-2010
20100249424METHOD FOR PREPARING 5-HALOALKYL-4,5-DIHYDROISOXAZOLE DERIVATIVES - Disclosed is a method for preparing a compound of Formula 109-30-2010
20100280251PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES - Disclosed is a method for preparing a compound of Formula 1 comprising contacting a compound of Formula 2 with a metal cyanide reagent, a copper(I) salt reagent, an iodide salt reagent and at least one compound of Formula 311-04-2010
20110009638METHOD FOR PREPARING 3-TRIFLUOROMETHYL CHALCONES - Disclosed is a method for preparing a compound of Formula 1 wherein Q and Z are as defined in the disclosure comprising distilling water from a mixture comprising a compound of Formula 2, a compound of Formula 3, a base comprising at least one compound selected from the group consisting of alkaline earth metal hydroxides of Formula 4 wherein M is Ca, Sr or Ba, alkali metal carbonates of Formula 4a wherein M01-13-2011
20120277442METHOD FOR PREPARING 5-HALOALKYL-4, 5-DIHYDROISOXAZOLE DERIVATIVES - Disclosed is a method for preparing a compound of Formula 111-01-2012

Patent applications by Gary David Annis, Landenberg, PA US

James Stacy Annis, Stevensville, MI US

Patent application numberDescriptionPublished
20120081992STAND MIXER WIPING BEATER - A mixing beater for a small appliance includes a metallic frame including an arm; a rigid plastic shell extending over the arm; and only one scraper. The scraper extends over the rigid plastic shell and has a flexible blade configured to contact an inner surface of a mixing bowl when viewed in a first plane.04-05-2012
20120081993STAND MIXER WIPING BEATER WITH ADDITIONAL FEATURES - A mixing beater for a stand mixer includes a metallic frame having an arm, a plastic shell extending over the arm, and a scraper that extends over the plastic shell. The scraper has a wiping blade configured to contact an inner surface of a mixing bowl of the stand mixer.04-05-2012

Jeffrey Annis, Waukesha, WI US

Patent application numberDescriptionPublished
20110242720MAGNETIC CORE COUPLING IN A CURRENT TRANSFORMER WITH INTEGRATED MAGNETIC ACTUATOR - A system comprising a magnetic actuator, a current transformer and operational electronics in a dual-coil circuit breaker. The system includes an inline, but non concentric, implementation of the primary and secondary coils to maintain a narrow width suitable for retrofitting in standard industrial rack mounted enclosures. The system further comprises an I-shaped lamination stack that is designed to abut on the ends of an upper and lower plate of the current transformer. The I-shaped lamination stack significantly increases the overlap between the lamination and the upper and lower plates, which results in lower magnetic reluctance and improves magnetic coupling.10-06-2011
20110267722COST EFFECTIVE DESIGN FOR A CURRENT TRANSFORMER WITH AN INTEGRATED MAGNETIC ACTUATOR - A system comprising a magnetic actuator, a current transformer and operational electronics in a dual-coil circuit breaker. The system includes an inline, but non concentric, implementation of the primary and secondary coils to maintain a narrow width suitable for retrofitting in standard industrial rack mounted enclosures. The system further comprises a split core design that is integrated into an upper and lower plate which slide together and are retained by a secondary coil bobbin. Typically, the two parts of the split core can be manufactured into net shapes by utilizing a powder metal or metal injection molding process. Moreover, the split core design disclosed herein can reduce costs and time associated with manufacturing and assembly of the current transformer.11-03-2011

Jeffrey R. Annis, Waukesha, WI US

Patent application numberDescriptionPublished
20120081202HIGH SPEED TRANSFORMER - Embodiments of the present invention provide novel techniques for creating a high speed transformer such as a pulse transformer. In particular, a secondary coil of the high speed transformer may include a single turn. The use of a single turn secondary coil simplifies the design and manufacture of the transformer and aids in more efficient inspections. Further, the single turn secondary coil transformer may reduce the number of vias used to interconnect the components of the transformer. Additionally, the embodiments described herein may significantly improve voltage isolation by single turn coils, and eliminate vias between board layers.04-05-2012

Jeffrey Ramsey Annis, Waukesha, WI US

Patent application numberDescriptionPublished
20090094820Contractor Assembly With Arc Steering System - A contactor assembly includes a stationary contact, an arc contact, an arc arrestor, and a magnetic intensifier. The magnetic intensifier is constructed to be secured in generally close proximity to the stationary contact. During communication of power through the contactor assembly, the magnetic intensifier accentuates a magnetic field associated with the stationary contact and increases the magnitude of a magnetic force directed to the arc arrestor. A pair of arc guides extend along the magnetic intensifier and, cooperatively with the magnetic force, ensure efficient, repeatable, and expedient transfer of a circuit termination arc to the arc arrestor. Such a construction increases the operable range and lifecycle of the contactor by reducing the damage associated with propagation of the circuit termination arc.04-16-2009
20090102585Contactor Assembly With Arc Steering System - A contactor assembly includes a stationary contact, an arc contact, an arc arrestor, and a magnetic intensifier. The magnetic intensifier is constructed to extend in generally close proximity to one of the stationary contact and the arc contact. During communication of power through the contactor assembly, the magnetic intensifier manipulates a magnetic field associated with current passing through the contactor assembly and increases the magnitude of a magnetic force directed to the arc arrestor. Preferably, the magnetic intensifier is formed integrally with a turnback associated with one of the stationary contact or the arc contact. Such a construction simplifies the manufacture and assembly of the contactor assembly and provides efficient and repeatable arc suppression.04-23-2009
20110133870Contactor Assembly With Arc Steering System - A contactor assembly includes a stationary contact, an arc contact, an arc arrestor, and a magnetic intensifier. The magnetic intensifier is constructed to be secured in generally close proximity to the stationary contact. During communication of power through the contactor assembly, the magnetic intensifier accentuates a magnetic field associated with the stationary contact and increases the magnitude of a magnetic force directed to the arc arrestor. A pair of arc guides extend along the magnetic intensifier and, cooperatively with the magnetic force, ensure efficient, repeatable, and expedient transfer of a circuit termination arc to the arc arrestor. Such a construction increases the operable range and lifecycle of the contactor by reducing the damage associated with propagation of the circuit termination arc.06-09-2011

Patent applications by Jeffrey Ramsey Annis, Waukesha, WI US

Kent V. Annis, Burnsville, MN US

Patent application numberDescriptionPublished
20090104864TOOL FOR WORKING ON A SURFACE - Embodiments of the present disclosure provide working tools that provide suction to a working surface and/or dust removal from a working surface. One embodiment of a tool includes a tool support having an upper surface and a sidewall defining a cavity defined by the sidewall and the upper surface. The tool includes a base attached to the upper surface of the tool support and a vacuum attachment structure attached to the base. The attachment structure includes a connector member having an opening in a first end for releasable attachment to a vacuum source.04-23-2009

Patent applications by Kent V. Annis, Burnsville, MN US

Kyle Gary Annis, Hummelstown, PA US

Patent application numberDescriptionPublished
20130034984LATCH FOR A CARD EDGE CONNECTOR SYSTEM - A latch for securing a circuit card assembly to a circuit board mounted card edge connector includes first and second arms disposed on opposite ends of the card edge connector. The first and second arms define a reception space that receives the circuit card assembly. The first arm has a deflectable spring latch that is movable between a released position and a latched position. The circuit card assembly is secured by the spring latch in the latched position. The second arm has a latch hook that is configured to hook around and engage a portion of the circuit card assembly during mating of the circuit card assembly and the card edge connector. The latch hook defines a pivot point for pivoting the circuit card assembly into the card edge connector during mating of the circuit card assembly and the card edge connector.02-07-2013

Ted Annis, Ann Arbor, MI US

Patent application numberDescriptionPublished
20090096219ENERGY GENERATION APPARATUS AND METHODS BASED UPON MAGNETIC FLUX SWITCHING - In an electrical energy generator, at least one permanent magnet generates flux and a magnetizable member forms the single flux path. An electrically conductive coil is wound around the magnetizable member, and a plurality of flux switches are operative to sequentially reverse the flux from the magnet through the member, thereby inducing electrical current in the coil. A “Figure-8” construction comprises two continuous loops of magnetizable material sharing a magnetizable member common to both loops. An alternative configuration uses stacked loops and a separate piece of material acting as the magnetizable member. One end of the magnet is coupled to one of the loops, with the other end being coupled to the other loop. Each loop further includes two flux switches operated in a 2×2 sequence to sequentially reverse the flux through the magnetizable member. A relatively small amount of electrical power is used to control the magnetic flux of a permanent magnet by switching the flux between alternate paths. The resulting power from the switched magnetic flux yields substantially more power than the power required for the input switching.04-16-2009

Theodore C. Annis, Ann Arbor, MI US

Patent application numberDescriptionPublished
20120171249COMPOSITIONS FOR INACTIVATING PATHOGENIC MICROORGANISMS, METHODS OF MAKING THE COMPOSITIONS, AND METHODS OF USE THEREOF - Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.07-05-2012