Patent application number | Description | Published |
20110250670 | LIGHT ENERGY-INDUCED STABILITY OF BIOMATERIALS - Disclosed are methods and apparatuses for stabilizing labile biomolecules in an aqueous solution without the use of chemicals. For example, some embodiments involve exposing an aqueous solution of a labile biomolecule, such as a protein, to light energy to stabilize the biomolecule in the solution. | 10-13-2011 |
20120021010 | ANTIPLATELET AGENT AND METHODS OF USING THE SAME - Disclosed herein are compositions and methods for inhibiting platelet aggregation in a patient in need thereof. The compositions and methods use superparamagnetic iron oxide nanoparticles (SPIONs), which are shown to inhibit aggregation of platelets. Such methods are useful in preventing blood clotting in diseases such as acute coronary syndrome. Also disclosed are in vitro methods of sensing platelet function using SPIONs. | 01-26-2012 |
20120021453 | LABEL-FREE CELL SORTING USING NEAR INFRARED EMISSION - Disclosed are methods and systems for identifying and sorting cells based on a near-infrared emission pattern of the cell in response to excitation at 630±nm. The NIR emission pattern can be used for monitoring and sorting of cells in a label-free manner, and thus provides a positive method for selecting cells, such as stem cells, for use in therapy. | 01-26-2012 |
20120206721 | NIR FLUORESCENCE OF HEAVY WATER - A method includes detecting D | 08-16-2012 |
20120267551 | APPARATUS AND METHODS FOR CHIRALITY DETECTION - Technologies are generally described for systems and methods for detecting chiral properties of materials and separating materials based on their chiral properties. A chiral vector is constructed from anisotropy properties of a polarization-dependent output signal from a sample. Different types of molecules from the sample can be differentiated based on a magnitude of the chiral vector. Chiral properties of the sample can be detected based on an angle of the chiral vector. The output signal can be a fluorescent emission from the sample and can be used to detect chiral properties of a substantially opaque sample. | 10-25-2012 |
20130027706 | NANO SENSING OF TEMPERATURE USING EQUAL INTENSITY DOUBLE PLASMON RESONANCE (EIDPR) - Technologies are generally described for providing and using a material including: a template molecule; a first cluster of one or more nanoparticles located at a first site on the template molecule; and a second cluster of one or more nanoparticles located at a second site on the template molecule and spaced apart from the first cluster. In some embodiments, the first and second clusters of nanoparticles exhibit a plasmon resonance having a first resonant peak and a second resonant peak. | 01-31-2013 |
20130300865 | STATIC MAGNETIC FIELD INDUCED DIFFERENTIAL FLUORESCENCE EMISSION - Exposure to a static magnetic field changes the fluorescence intensity of a wide range of fluorophores, including small molecules (e.g., tryptophan), complex organizations of fluorophores (e.g., proteins), quantum dots, nanoparticles, and other materials. Different materials may experience different changes in fluorescence emission upon exposure to a magnetic field—for instance, some or all of a material's fluorescence emission spectrum may increase in amplitude or shift in wavelength. Different materials may also experience different changes in relaxation time, which is the time constant associated with fluorescence decay. These magnetically induced differences fluorescence emission spectra and decay can be used to identify, classify, or sort materials noninvasively. | 11-14-2013 |
20140107942 | APPARATUS AND METHODS FOR CHIRALITY DETECTION - Technologies are generally described for systems and methods for detecting chiral properties of materials and separating materials based on their chiral properties. A chiral vector is constructed from anisotropy properties of a polarization-dependent output signal from a sample. Different types of molecules from the sample can be differentiated based on a magnitude of the chiral vector. Chiral properties of the sample can be detected based on an angle of the chiral vector. The output signal can be a fluorescent emission from the sample and can be used to detect chiral properties of a substantially opaque sample. | 04-17-2014 |
20140193890 | THERMOSTABLE ENZYMES AND METHODS OF MAKING AND USING THE SAME - Provided herein are compositions and methods for enhancing enzyme activity, half-life and/or thermostability. Also provided herein are compositions and methods including the enhanced enzymes. Also provided herein are methods and compositions related to improved pectinolytic enzymes, such as pectate lyase, which exhibit enhanced activity, thermostability and/or longer half-life. | 07-10-2014 |
20140377792 | HALF-FREQUENCY SPECTRAL SIGNATURES - A technique for determining whether or not a fluorescent material exhibits a directionally dependent property, such as anisotropy or chirality, involves illuminating the particle at its excitation wavelength to stimulate fluorescent emission at both a full-frequency (fundamental) wavelength and a half-frequency wavelength. The ratio of the full-frequency signal strength to the half-frequency signal strength provides an indication of the sample's directionally dependent property. This half-frequency spectral analysis can be used to sort anisotropic particles suspended in fluid flowing through a flow cytometer. For instance, the present technique may be used to separate racemic mixtures of chiral enantiomers of cells, pharmaceutical compounds, and other samples. | 12-25-2014 |
20150044710 | ENZYMATIC SENSORS AND METHODS FOR THEIR PREPARATION AND USE - Disclosed herein are methods, compositions and devices for detecting oxygen in various samples such as environmental and biological samples. | 02-12-2015 |
20150044731 | PSYCHROPHILIC ENZYMES COMPOSITIONS AND METHODS FOR MAKING AND USING SAME - Enzyme compositions with enhanced enzyme activity and/or thermophilic and psychrophilic stability are described. Additionally, methods and kits for making and using the enzyme compositions are provided. | 02-12-2015 |
20150079656 | ENZYME STABILIZATION BY CARBON NANOTUBES - The present technology provides for enzyme compositions with enhanced enzyme activity, thermophilic and psychrophilic stability. Additionally, the present technology provides for methods and kits for making and using the enzyme compositions. | 03-19-2015 |