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Anikó

Anikó Keller-Pintér, Csongrad HU

Patent application numberDescriptionPublished
20090305329INTRACELLULAR TARGETING OF MOLECULES - The present invention provides methods for intracellular and/or nuclear targeting of an agent capable of specifically binding to syndecan-4. The present invention further provides methods for the modification of the intracellular and/or nuclear targeting of said agent, as well methods for identifying compounds capable of modifying the syndecan-4 delivery pathway. The present invention further provides experimental kits to perform the methods according to the invention.12-10-2009

Anikó Keller-Pintér, Csongrad HU

Patent application numberDescriptionPublished
20090305329INTRACELLULAR TARGETING OF MOLECULES - The present invention provides methods for intracellular and/or nuclear targeting of an agent capable of specifically binding to syndecan-4. The present invention further provides methods for the modification of the intracellular and/or nuclear targeting of said agent, as well methods for identifying compounds capable of modifying the syndecan-4 delivery pathway. The present invention further provides experimental kits to perform the methods according to the invention.12-10-2009
20110124572SYNDECAN-4 IS A REGULATOR OF RAC1-GTP - The present invention provides a method for modulating the activity of Rac1, comprising modifying the phosphorylation state of Ser179 in syndecan-4 through influencing the interaction between syndecan-4 and the guanin nucleotide exchange factor of Rac1 (RacGEF) named Tiam1 in a GTP-dependent manner. In particular, methods are provided for enhancing the epithelial phenotype of a cell and for initiating the polarization of a cell by increasing the de-phosphorylation of said Ser179 of syndecan-4, and for enhancing the migratory phenotype of a cell and for initiating the neuronal differentiation of a cell by increasing the phosphorylation of said Ser179 of syndecan-4. Polypeptides for use in modulating the activity of the small GTPase Rac are also provided, as well as a method for identifying an agent capable of indirectly modulating the activity of the small GTPase Rac 1.05-26-2011

Anikó Tegdes, Budapest HU

Patent application numberDescriptionPublished
20100209967PROCESS FOR THE SYNTHESIS OF 9A-HYDROXY-STEROIDS - The present invention relates to a novel selective synthesis of 9α-hydroxy-steroid derivatives of the general formula (I) (I)—wherein the meaning of -A-A′- is —CH08-19-2010

Anikó Tegdes, Budapest HU

Patent application numberDescriptionPublished
20100209967PROCESS FOR THE SYNTHESIS OF 9A-HYDROXY-STEROIDS - The present invention relates to a novel selective synthesis of 9α-hydroxy-steroid derivatives of the general formula (I) (I)—wherein the meaning of -A-A′- is —CH08-19-2010