Patent application number | Description | Published |
20120083868 | METHODS AND APPARATUSES FOR FLOW RESTORATION AND IMPLANTING MEMBERS IN THE HUMAN BODY - A medical device for blood flow restoration and/or for use as an implantable member in a human vessel includes a self-expanding member, a guidewire, and a connection mechanism. The self-expanding member includes a plurality of cells and filaments having specific ranges of thicknesses, widths, and heights. The self-expanding member can take on a volume-reduced coiled form with overlapped edges, and can generate optimal radial forces against a vessel wall and/or thrombus when deployed and expanded. | 04-05-2012 |
20120143237 | VASCULAR REMODELING DEVICE - Described herein are vascular remodeling devices that include a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchors the device in an afferent vessel of a bifurcation. The distal section expands from the compressed delivery state to an expanded state that may be substantially planar, approximately semi-spherical, umbrella shaped, or reverse umbrella shaped. The distal section is positioned in a bifurcation junction across the neck of an aneurysm or within an aneurysm. The intermediate section allows perfusion to efferent vessels. Before or after the device is in position, embolic material may be used to treat the aneurysm. The distal section can act as a scaffolding to prevent herniation of the embolic material. The device can be used for clot retrieval with integral distal embolic protection. | 06-07-2012 |
20120143317 | VASCULAR REMODELING DEVICE - Described herein are vascular remodeling devices that include a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchors the device in an afferent vessel of a bifurcation. The distal section expands from the compressed delivery state to an expanded state that may be substantially planar, approximately semi-spherical, umbrella shaped, or reverse umbrella shaped. The distal section is positioned in a bifurcation junction across the neck of an aneurysm or within an aneurysm. The intermediate section allows perfusion to efferent vessels. Before or after the device is in position, embolic material may be used to treat the aneurysm. The distal section can act as a scaffolding to prevent herniation of the embolic material. The device can be used for clot retrieval with integral distal embolic protection. | 06-07-2012 |
20120290067 | VASCULAR REMODELING DEVICE - Described herein are flexible implantable devices or stents that can conform to the shape of vessels of the neurovasculature. In some embodiments, the devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. In some embodiments, a vascular remodeling device includes a first section and a protruding section. During deployment, the device expands from a compressed configuration to an expanded configuration. The first section anchors the device in an afferent vessel and/or in an efferent vessel of a bifurcation and the protruding section is positioned in the junction of the bifurcation having an aneurysm and across the neck of the aneurysm or at least partially within the aneurysm. | 11-15-2012 |
20120296361 | VASCULAR REMODELING DEVICE - A vascular remodeling device and methods for its use are provided. The device can be positionable at a junction of a bifurcation having an aneurysm and that defines afferent and efferent vessels. Ends of the device can be at least partially inserted into the aneurysm or can anchor the device by being at least partially inserted into efferent vessels. The device can act as a scaffolding to inhibit dislodging of objects out of the aneurysm. The device can permit perfusion to the efferent vessels. Embolic material can be inserted in the aneurysm before, during, and/or after positioning the device. | 11-22-2012 |
20120296362 | VASCULAR REMODELING DEVICE - A vascular remodeling device is provided that can comprise a proximal section, an intermediate section, and a distal section. During deployment, the proximal section can expand from a compressed delivery state to an expanded state and anchor the device in the afferent vessel of a bifurcation. The distal section can comprise at least one embolization coil that can be positioned within an aneurysm to treat the aneurysm and expand from the compressed delivery state to an expanded state upon deployment. The intermediate section can allow perfusion to efferent vessels. Before, during, and/or after the device is positioned, additional embolic material can be used to treat the aneurysm. | 11-22-2012 |
20140074144 | RETRIEVAL CATHETER WITH EXPANDABLE TIP - Catheters of the present disclosure include a catheter shaft and an expandable tip, which can retrieve materials slightly larger than an inner diameter of the catheter shaft. The tip may be expandable such that it can easily transform from a first size and shape to a second size and shape to aid in the retrieval of the materials (i.e., the thrombus, embolus, or foreign body). Catheter tips may be expanded by inflation, removal of a constraining member, or an input such as heat, light, or electrical energy. | 03-13-2014 |
20150209133 | VASCULAR REMODELING DEVICE - Described herein are flexible implantable devices or stents that can conform to the shape of vessels of the neurovasculature. In some embodiments, the devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. In some embodiments, a vascular remodeling device includes a first section and a protruding section. During deployment, the device expands from a compressed configuration to an expanded configuration. The first section anchors the device in an afferent vessel and/or in an efferent vessel of a bifurcation and the protruding section is positioned in the junction of the bifurcation having an aneurysm and across the neck of the aneurysm or at least partially within the aneurysm. | 07-30-2015 |
20150297375 | METHODS AND APPARATUSES FOR FLOW RESTORATION AND IMPLANTING MEMBERS IN THE HUMAN BODY - A medical device for blood flow restoration and/or for use as an implantable member in a human vessel includes a self-expanding member, a guidewire, and a connection mechanism. The self-expanding member includes a plurality of cells and filaments having specific ranges of thicknesses, widths, and heights. The self-expanding member can take on a volume-reduced coiled form with overlapped edges, and can generate optimal radial forces against a vessel wall and/or thrombus when deployed and expanded. | 10-22-2015 |
Patent application number | Description | Published |
20090143415 | Tetrodotoxin And Its Derivatives For The Treatment Of Central-Nervously Derived Neuropathic Pain - The present invention refers to the use of a sodium channel blocker such as tetrodotoxin or saxitoxin, their analogues and derivatives as well as their physiologically acceptable salts, in medicinal products for human therapeutics for the treatment of central-nervously derived neuropathic pain. | 06-04-2009 |
20100048592 | Use of sodium channel blockers for the management of musculoskeletal pain - The invention provides methods for managing musculoskeletal pain. The compounds useful in the methods of the invention are blockers of sodium ion channels, and in particular compounds that bind to the SS1 or SS2 extracellular mouth of the a-subunit thereof. Particularly useful compounds are saxitoxin and its derivatives and analogues and tetrodotoxin and its derivatives and analogues. | 02-25-2010 |
20100075992 | Tetrodotoxin and its derivatives for the treament of peripheral-nervously derived neuropathi pain - The present invention refers to the use of a sodium channel blocker such as tetrodotoxin or saxitoxin, their analogues and derivatives as well as their physiologically acceptable salts, in medicinal products for human therapeutics for the treatment of peripheral-nervously derived neuropathic pain. | 03-25-2010 |
20100144767 | Use of sodium channel blockers for the treatment of visceral pain or pain caused by cancer treatment - The invention provides methods for treating visceral pain and pain associated with therapy. The compounds useful in the methods of the invention are blockers of sodium ion channels, and in particular compounds that bind to the SS1 or SS2 extracellular mouth of the α-subunit thereof. Particularly useful compounds are saxitoxin and its derivatives and analogues and tetrodotoxin and its derivatives and analogues. | 06-10-2010 |
Patent application number | Description | Published |
20090155445 | TINGLING AND SALIVATING COMPOSITIONS - A sensate composition that includes a salivating component, a tingling component and a flavor, the salivating component being formed of at least a mixture of citric, malic and succinic acid, or one of each of their salts, and the tingling component being formed of a Jambu oleoresin, spilanthol, any extract containing either or both, and their mixtures. The sensate composition allows the preparation of consumer products having improved salivating properties. | 06-18-2009 |
20090208604 | FAT, WAX OR OIL-BASED FOOD INGREDIENT COMPRISING ENCAPSULATED FLAVORS - The present invention relates to food ingredients, or entire food products, that contain fats or oils, and, dispersed with the fat or oil, flavor capsules. The flavor capsules include a micro-organism, a surrounding matrix component and at least one flavor, which is mainly present within the micro-organism. The food or food ingredients may be used as such, or as coatings or fillings for conventional food products. The fat or oil based food ingredient of the invention has increased flavor intensity if compared to similar food ingredients in which the flavor is not encapsulated. The flavors are immediately released upon consumption of the food or food ingredient. Owing to the particular encapsulation of flavors, the food ingredient is largely resistant to flavor evaporation due to elevated temperatures during food manufacturing processes. | 08-20-2009 |
Patent application number | Description | Published |
20090144561 | Method and System for Software Protection Using Binary Encoding - Software is protected by encoding the target software instructions and decoding the target instructions. | 06-04-2009 |
20150106872 | METHOD OF INSTRUCTION LOCATION RANDOMIZATION (ILR) AND RELATED SYSTEM - A method and system for relocating executable instructions to arbitrary locations are disclosed. The instruction relocation may be arbitrary or random, and may operate on groups of instructions or individual instructions. Such relocation may be achieved through hardware or software, and may use a virtual machine, software dynamic translators, interpreters, or emulators. Instruction relocation may use or produce a specification governing how to relocate the desired instructions. Randomizing the location of instructions provides defenses against a variety of security attacks. The disclosed embodiments provide many advantages over other instruction relocation techniques, such as low runtime overhead, no required user interaction, applicability post-deployment, and the ability to operate on arbitrary executable programs. | 04-16-2015 |
20150304337 | METHODS, SYSTEMS AND COMPUTER READABLE MEDIA FOR DETECTING COMMAND INJECTION ATTACKS - Methods and systems are described for detecting command injection attacks. A positive, taint inference method includes receiving signature fragments on one hand, converting command injection instructions into command fragments on another hand, thus identifying potential attacks upon the condition that a command injection instruction includes critical untrusted parts by using signature fragments. A system detects command injection attacks using this kind of method, and remediates and rejects potential attacks. | 10-22-2015 |
Patent application number | Description | Published |
20100137495 | EXTERIOR PAINT FORMULATION - The present invention provides increased stain resistance, tannin blocking, adhesion, and various other properties. A composition in accordance with the principles of the present invention comprises at least two binders, nanoparticle pigment, and pigmentary titanium dioxide. In one embodiment, the present invention relates to a coating on a substrate wherein the coating has two binders, nanoparticle metal oxide pigment, and pigmentary titanium dioxide. Various additives may be included to formulate paint as known in the art. | 06-03-2010 |
20110224349 | Exterior Deep Base Paint Formulation - The present invention provides increased stain resistance, tannin blocking, adhesion, and various other properties. A composition in accordance with the principles of the present invention comprises at least three binders, nanoparticle pigment, and pigmentary titanium dioxide. In one embodiment, the present invention relates to a coating on a substrate wherein the coating has three binders, nanoparticle metal oxide pigment, and pigmentary titanium dioxide. Various additives may be included to formulate paint as known in the art. | 09-15-2011 |
Patent application number | Description | Published |
20130130265 | METHODS AND DEVICES FOR OBTAINING AND ANALYZING CELLS - A method for concentrating and isolating nucleated cells, such as maternal and fetal nucleated red blood cells (nRBCs), in a maternal whole blood sample. The invention also provides methods and apparatus for preparing to analyze and analyzing the sample for identification of fetal genetic material as part of prenatal genetic testing. The invention also pertains to methods and apparatus for discriminating fetal nucleated red blood cells from maternal nucleated red blood cells obtained from a blood sample taken from a pregnant woman. | 05-23-2013 |
20130130929 | METHODS, DEVICES, AND KITS FOR OBTAINING AND ANALYZING CELLS - A method for concentrating and isolating nucleated cells, such as maternal and fetal nucleated red blood cells (nRBCs), in a maternal whole blood sample. The invention also provides methods and apparatus for preparing to analyze and analyzing the sample for identification of fetal genetic material as part of prenatal genetic testing. The invention also pertains to methods and apparatus for discriminating fetal nucleated red blood cells from maternal nucleated red blood cells obtained from a blood sample taken from a pregnant woman. | 05-23-2013 |
20130130930 | METHODS AND DEVICES FOR OBTAINING AND ANALYZING CELLS - A method for concentrating and isolating nucleated cells, such as maternal and fetal nucleated red blood cells (nRBCs), in a maternal whole blood sample. The invention also provides methods and apparatus for preparing to analyze and analyzing the sample for identification of fetal genetic material as part of prenatal genetic testing. The invention also pertains to methods and apparatus for discriminating fetal nucleated red blood cells from maternal nucleated red blood cells obtained from a blood sample taken from a pregnant woman. | 05-23-2013 |