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Andrew Turner
Andrew Turner, King Of Prussia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080220002 | MODIFIED TRANSFERIN-ANTIBODY FUSION PROTEINS - Modified fission proteins of transferrin and therapeutic proteins or peptides, preferably antibody variable regions, with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor. | 09-11-2008 |
| 20110091543 | ORAL DELIVERY OF MODIFIED TRANSFERRIN FUSION PROTEINS - Pharmaceutical compositions containing modified fusion proteins of transferrin and therapeutic proteins or peptides with increased serum half-life or increased serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, but does exhibit binding to iron and/or the transferrin receptor. Such fusion proteins may be administered orally. | 04-21-2011 |
| 20110092677 | MODIFIED TRANSFERIN-ANTIBODY FUSION PROTEINS - Modified fusion proteins of transferrin and therapeutic proteins or peptides, preferably antibody variable regions, with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor. | 04-21-2011 |
Andrew Turner, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100316623 | PHENYLALANINE HYDROXYLASE FUSION PROTEIN AND METHODS FOR TREATING PHENYLKETONURIA - The present invention provides Phenylalanine Hydroxylase (PAH) fusion proteins and pharmaceutical compositions comprising the same, as well as encoding polynucleotides and vectors, and methods for treating hyperphenylalaninemia, including PKU, by enzyme replacement therapy. The fusion proteins have phenylalanine hydroxylase activity when administered: and have an increased half-life or persistence in circulation, as compared to unfused counterparts. The PAH fusion proteins are suitable for enzyme replacement therapy in PKU patients by converting phenylalanine in the circulation to tyrosine, thereby controlling phenylalanine levels. | 12-16-2010 |
Andrew Turner, Heighington GB
| Patent application number | Description | Published |
|---|---|---|
| 20100140240 | POSITIONING MEANS AND METHOD OF USE THEREOF - A positioning device ( | 06-10-2010 |
Andrew Turner, Morrisville, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090275481 | Anchored Transferrin Fusion Protein Libraries - Fusion proteins comprising a transferrin moiety, a stalk moiety, and cell wall linking member and peptide libraries thereof are disclosed. The present invention includes a method of screening peptide libraries displayed in fusion proteins expressed by host cells. The fusion proteins of the present invention include transferrin fusion proteins capable of expression in yeast. | 11-05-2009 |
Andrew Turner, Cheshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20080269294 | Benzamide Compounds Useful as Histone Deacetylase Inhibitors - The invention concerns benzamide compounds of formula (I), wherein R | 10-30-2008 |
Andrew Turner, Warwickshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20080220930 | Linear Actuator - A linear actuator includes permanent magnet annuli arranged about an armature core for axial movement in a tubular stator upon energisation of coils arranged in concentric association with the armature. The stator has portions extending radially inwards of the coils and towards one another beneath each coil, which define a spacing between the coil and the armature. The annuli have a substantially radially magnetised structure and the coils are configured for single phase power input. In one embodiment (FIG. | 09-11-2008 |
Andrew Turner, Nashville, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20110112933 | SYSTEM AND METHOD OF MEDIA DISTRIBUTION MANAGEMENT - There is a media distribution system and method configured to distribute media over a computerized network including a media distribution module configured to selectively permit access to media over a computerized network and including a user interface module. The media distribution system also includes an operational administration module in communication with the media distribution module and configured to facilitate operational management of the media distribution module by selectably altering operational parameters of the media distribution module. In addition, the media distribution system includes a supervisory administration module in communication with the operational administration module and configured to selectably determine operational parameters available to the operational administration module for control. Furthermore, the media distribution system includes a network module in communication with the media distribution module and configured to transfer data over a computerized network. | 05-12-2011 |