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Andreou
Andreas G. Andreou, Baltimore, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100245809 | DEEP SUBMICRON AND NANO CMOS SINGLE PHOTON PHOTODETECTOR PIXEL WITH EVENT BASED CIRCUITS FOR READOUT DATA-RATE REDUCTION COMMUNICATION SYSTEM - An avalanche photodiode and a sensor array comprising an array of said avalanche photodiodes is disclosed. Then avalanche photodiode comprises a substrate of a first conductivity type; a first well of a second conductivity type formed within the substrate; a second well of the second conductivity type formed substantially overlying and extending into the first well; a heavily doped region of the first conductivity type formed substantially overlying and extending into the first well, the junction between the heavily doped region and the second well forming an avalanche multiplication region; a guard ring formed from a first conductivity material positioned substantially about the periphery of the multiplication region at least partially underlying the heavily doped region; and an outer well ring of the second conductivity type formed about the perimeter of the deep well and the guard ring. The sensor array comprises a plurality of pixel elements, each of the pixel elements being configured to operate on discrete value continuous time (DVCT) basis. Each of the pixel elements can include the avalanche photodiode previously described. | 09-30-2010 |
Ioanna Andreou, Hilden DE
| Patent application number | Description | Published |
|---|---|---|
| 20100227406 | METHOD FOR PURIFYING CELLS, RECOVERING CELLS, AND TRANSFECTING CELLS GENTLY - The present invention relates to a process for cell purification, for cell recovery from cultures and for the transfection of the cells under especially gentle conditions, where this process can additionally be coupled with subsequent isolation and purification of polynucleotides from the optionally transfected cells, and a kit and a device for the implementation of this process. | 09-09-2010 |
Ioanna Andreou, Koln DE
| Patent application number | Description | Published |
|---|---|---|
| 20090197332 | Modified Short Interfering RNA - The present invention refers to a double-stranded siRNA molecule comprising a sense Strand and an antisense Strand which is essentially complementary to the sense Strand, each of the sense and the antisense Strands comprising at least 17 nucleotides (nt), the siRNA further comprising at least one overhang at the 5′ and/or 3′ end, wherein the overhang residue or overhang residues are chemically modified and selected independently from each other from the group consisting of: (a) 2′-deoxy modified nucleotides; (b) 2′-methoxy modified nucleotides; (c) two nucleosides linked by a 3′ to 5′ or 2′ to 5′ formacetal linkage; (d) nucleotides modified at the 2′-position by a -0-CH | 08-06-2009 |
| 20090317906 | GENE SILENCING USING SENSE DNA AND ANTISENSE RNA HYBRID CONSTRUCTS COUPLED TO PEPTIDES FACILITATING THE UPTAKE INTO CELLS - The present invention generally relates to gene silencing using sense DNA (sDNA)-antisense RNA (aRNA) hybrids wherein the sense DNA strand is coupled to a peptide which facilitates the uptake of the hybrid into cells. | 12-24-2009 |
Ioanna Andreou, Koeln DE
| Patent application number | Description | Published |
|---|---|---|
| 20090306177 | Modulation of Immunostimulatory Properties of Short Interfering Ribonucleic Acid (Sirna) by Nucleotide Modification - Double-stranded short interfering ribonucleic acid (siRNA) are modified to reduce or eliminate their immunostimulatory effect without significantly affecting their gene silencing effect. Modified siRNA include one or more 2′ sugar modifications and, optionally, internucleotide linkages on the sense strand. Compositions containing the modified siRNA and methods of making and using the modified siRNA are disclosed. New and previously characterized siRNA can be synthesized to incorporate modifications according to the invention. | 12-10-2009 |
Michael Andreou, Oakville CA
| Patent application number | Description | Published |
|---|---|---|
| 20110298527 | REAL TIME DYNAMIC OPTIMIZATION OF DEADTIME - A deadtime optimization apparatus and method may determine when it is safe to turn a switch ON, eliminating the need to have a switch controller purposely insert a deadtime period in the algorithm (i.e., it can go back to producing ideal PWM). Since the decision of when it is safe to turn ON the switch may be achieved through measurement, it is expected that the length of time may change for each pulse as the operating conditions change. Therefore, the apparatus and methods of the present invention may take on a dynamic characteristic because the safe to turn ON (STTO) time may vary for each pulse. | 12-08-2011 |
Michael Paul Andreou, West Sussex GB
| Patent application number | Description | Published |
|---|---|---|
| 20080198379 | Device For Detection And Measurement Of A Target Compound Such As A Food Toxin - Apparatus comprising a holder for a sample which comprises a packing or coating capable of immobilising or isolating a target compound in a layer or band, an excitation unit that emits radiation that excites fluorescence in a target compound or derivatised target compound immobilised or isolated in the packing or coating, or in another moiety stimulated by the target compound, a detection unit that is sensitive to radiation emitted by a fluorescing target compound, derivative or target compound-stimulated moiety and outputs a signal proportional to the amount of radiation detected, means for relatively moving the sample cartridge and the detection unit whereby the radiation may be sensed and a processing unit that converts the output of the detector unit into a readable value related to the amount of target compound immobilised in the layer or band. | 08-21-2008 |
| 20100264332 | APPARATUS AND METHOD FOR DETECTION AND MEASUREMENT OF TARGET COMPOUNDS SUCH AS A FOOD TOXIN - A method for the detection or determination of a target comprising a plurality of target compounds, or derivatised target compounds, said method comprising: immobilising said target on a carrier, directing radiation at said target, said radiation being selected to cause said target to emit a relevant radiation, detecting said relevant radiation emitted by said target, and analysing said detected radiation to identify and/or quantify the plurality of target compounds in said target. | 10-21-2010 |