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Andreotti
Amy H. Andreotti, Ames, IA US
| Patent application number | Description | Published |
|---|---|---|
| 20080247953 | METHODS AND COMPOSITIONS FOR AFFECTING SUBSTRATE DOCKING OF KINASES IN MODULATING CELLULAR ACTIVITIES - The present invention relates to drug screening assays, therapeutic protocols and pharmaceutical compositions designed to target non-receptor tyrosine family kinases and components of the tyrosine kinase family signal transduction pathways. This includes primarily diseases or conditions associated with immune responses and can include treatment for cancers as well as various immune disorders. The invention reports a novel substrate SH2 domain docking mechanism apart from the kinase active site that is required for appropriate tyrosine phosphorylation by these tyrosine kinases. | 10-09-2008 |
| 20090010911 | METHODS AND COMPOSITIONS FOR AFFECTING CYCLOPHILIN A REGULATION OF KINASES IN MODULATING CELLULAR ACTIVITIES - The present invention relates to drug screening assays, therapeutic protocols and pharmaceutical compositions designed to target non-receptor tyrosine family kinases and components of the tyrosine kinase family signal transduction pathways. It has been previously reported by the inventors that a substrate SH2 domain docking mechanism apart from the kinase active site is required for appropriate tyrosine phosphorylation by these tyrosine kinases. According to the invention, it has been discovered that Cyclophilin A, the target of drugs such as cyclosporin A, mediates its regulatory effects by interacting with this remote SH2 domain, making modulation of this interaction possible for regulation and improved therapeutic intervention. | 01-08-2009 |
Claudio Andreotti, Munich DE
| Patent application number | Description | Published |
|---|---|---|
| 20090033364 | INTEGRATED CIRCUIT DEVICE FOR RECEIVING DIFFERENTIAL AND SINGLE-ENDED SIGNALS - An integrated circuit device includes a receiver that is capable of receiving and converting either differential input signals or two unrelated single-ended input signals. | 02-05-2009 |
Daniele Andreotti, Verona IT
| Patent application number | Description | Published |
|---|---|---|
| 20080269208 | Pyridine Derivatives and Their Use in the Treatment of Psychotic Disorders - There are provided according to the invention novel compounds of formula (I) or a pharmaceutically acceptable salt or solvate thereof: | 10-30-2008 |
| 20080306122 | Novel Compounds - Compounds of formula (I) wherein the variables are defined herein, pharmaceutical compositions thereof and methods for treatment using the same. | 12-11-2008 |
| 20090023757 | PROCESS FOR PREPARING BICYCLIC COMPOUNDS - The present invention relates to a novel process for preparing compounds of formula (IA), which are potent and specific antagonists of corticotropin-releasing factor (CRF) receptors, from intermediate compounds of formula (I), by a coupling reaction catalysed by copper. | 01-22-2009 |
| 20090170902 | COMPOUNDS WHICH POTENTIATE GLUTAMATE RECEPTOR AND USES THEREOF IN MEDICINE - Compounds of formula (I), salts and solvates thereof are provided: | 07-02-2009 |
| 20100048656 | GLYT1 TRANSPORTER INHIBITORS AND USES THEREOF IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS - Compounds of formula (I) or a salt thereof are provided: | 02-25-2010 |
| 20100152175 | Pyridine Derivatives and Their Use in The Treatment of Psychotic Disorders - There are provided according to the invention novel compounds of formula (I) or a pharmaceutically acceptable salt thereof: | 06-17-2010 |
Leonardo Andreotti, Ferrara IT
| Patent application number | Description | Published |
|---|---|---|
| 20110014433 | Multilayer paper material, method for its forming and method for obtaining three-dimensional containers - A multilayer papery material comprising at least one first sheet of three-dimensional structure and at least one second sheet fixedly coupled to the first sheet and defining empty spaces therein, wherein at least said second sheet is made of a papery material having a degree of extensibility of not less than 5% in all directions. | 01-20-2011 |
Stefano Andreotti, Modena IT
| Patent application number | Description | Published |
|---|---|---|
| 20110120059 | PACKAGING METHOD AND UNIT FOR PRODUCING SEALED PACKAGES OF A FOOD PRODUCT POURABLE INTO A TUBE OF PACKAGING MATERIAL - A method of producing a sealed package of a pourable food product involving feeding a tube of packaging material along an axis; moving a pair of first jaws and a pair of second jaws cyclically and alternately along sealing paths parallel to the axis, and along repositioning paths; moving the jaws, as they travel along the sealing paths, into a closed position in which the sealing members grip the tube and respectively form, at different times, a first and a second seal sealing the tube and defining respective opposite ends of the package; and moving the jaws, as they travel along the respective repositioning paths, into an open position, in which they are detached from the tube; acquiring a desired value of a quantity related to the package weight; and forming the second seal at a distance, which is a function of the value, from the first seal. | 05-26-2011 |