Patent application number | Description | Published |
20120045771 | METHOD FOR ANALYSIS OF NUCLEIC ACID POPULATIONS - The invention relates to a method for isolation of target molecules from a nucleic acid population. | 02-23-2012 |
20120108462 | MIRNA FINGERPRINT IN THE DIAGNOSIS OF LUNG CANCER - The present invention provides novel methods for diagnosing diseases based on the determination of specific miRNAs that have altered expression levels in disease states compared to healthy controls. | 05-03-2012 |
20120157336 | miRNA FINGERPRINT IN THE DIAGNOSIS OF DISEASES - The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls. | 06-21-2012 |
20120157337 | miRNA FINGERPRINT IN THE DIAGNOSIS OF MULTIPLE SCLEROSIS - The present invention provides novel methods for diagnosing diseases based on the determination of specific miR-NAs that have altered expression levels in disease states compared to healthy controls. | 06-21-2012 |
20120309645 | miRNA IN THE DIAGNOSIS OF OVARIAN CANCER - The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls. | 12-06-2012 |
20130035251 | miRNA FINGERPRINT IN THE DIAGNOSIS OF WILMS' TUMOUR - MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls. | 02-07-2013 |
20130245958 | ACCURATE COMPARISON AND VALIDATION OF SINGLE NUCLEOTIDE VARIANTS - A method is disclosed for validation of single nucleotide variants (SNV) in a sequence of interest. In at least one embodiment, the method includes: interrogating a BAM-file of the sequence of interest and a reference sequence file and producing a summary table for genomic coordinates of interest; generating a plurality of sequence reads from a sample of said sequence of interest; filtering sequence reads using a plurality of filter levels; extracting SNV counts for each strand for a genomic region of interest within the sequence of interest, resulting in ten SNV counts; for each genomic region of interest determining a rule based genotype decision and inferring a best genotype from the 10 counts; and creating a single consensus file for said sequence of interest including information of best genotype and a best quality for each genomic region of interest. | 09-19-2013 |
20140058752 | COMPUTER NETWORK FOR QUALITY TESTING CLINICAL TRIAL DATA - A computer network system and a method for quality testing input clinical trial data are disclosed. The trial data is recorded by way of a form provided on a patient device or a physician device and is passed on in an encrypted, anonymized form to a central server. A quality testing device is installed on the server in order to test the recorded medical data sets with regard to the quality thereof. The scope of the quality test is configurable. In the event of successful testing, an incentive attribute is read out from a database in order to generate an incentive signal and to transmit the signal to the respective terminal device. | 02-27-2014 |
20150031777 | miRNA FINGERPRINT IN THE DIAGNOSIS OF WILMS' TUMOUR - MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls. | 01-29-2015 |