| Patent application number | Description | Published |
|---|
| 20080268502 | Multiple Promoters and the Use Thereof For Gene Expression - The present invention relates to multiple promoters and to expression units comprising them; to the use thereof for regulating transcription and expression of genes; to expression cassettes which comprise multiple promoters or expression units of this kind; to vectors which comprise such expression cassettes; to genetically modified microorganisms which comprise vectors and/or expression units of this kind; and to processes for preparing biosynthetic products by culturing said genetically modified microorganisms. | 10-30-2008 |
| 20090029425 | PROCESS FOR THE PRODUCTION OF BETA-LYSINE - Process for the production of -lysine by constructing a recombinant microorganism which has a deregulated lysine 2,3-aminomutase gene and at least one deregulated gene selected from the group (i) which consists of aspartokinase, aspartatesemialdehyde dehydrogenase, dihydrodipicolinate synthase, dihydrodipicolinate reductase, tetrahydrodipicolinate succinylase, succinyl-amino-ketopimelate transaminase, succinyl-diamino-pimelate desuccinylase, diaminopimelate epimerase, diamino-pimelate dehydrogenase, arginyl-tRNA synthetase, diaminopimelate decarboxylase, pyruvate carboxylase, phosphoenolpyruvate carboxylase, glucose-6-phosphate dehydrogenase, transketolase, transaldolase, 6-phosphogluconolactonase, fructose 1,6-biphosphatase, homoserine dehydrogenase, phophoenolpyruvate carboxykinase, succinyl-CoA synthetase, methylmalonyl-CoA mutase, provided that if aspartokinase is deregulated as gene (i) at least a second gene (i) other than aspartokinase has to be deregulated, and cultivating said microorganism. | 01-29-2009 |
| 20090053778 | Microorganisms for producing sulfur-containing compounds - The present invention relates to microorganisms and methods for producing at least one sulfur-containing compound. | 02-26-2009 |
| 20090191610 | Microorganisms With Increased Efficiency for Methionine Synthesis - The present invention relates to methods for the production of microorganisms with increased efficiency for methionine synthesis, microorganisms with increased efficiency for methionine synthesis, and methods for determining the optimal metabolic flux for organisms with respect to methionine synthesis. | 07-30-2009 |
| 20090246838 | Process For The Production Of Cadaverine - Process for the production of cadaverine by constructing a recombinant microorganism which has a deregulated lysine decarboxylase gene and at least one deregulated gene selected from the group (i) which consists of aspartokinase, aspartatesemialdehyde dehydrogenase, dihydrodipicolinate synthase, dihydrodipicolinate reductase, tetrahydrodipicolinate succinylase, succinyl-amino-ketopimelate transaminase, succinyl-diamino-pimelate desuccinylase, diaminopimelate epimerase, diaminopimelate dehydrogenase, arginyl-tRNA synthetase, diaminopimelate decarboxylase, pyruvate carboxylase, phosphoenolpyruvate carboxylase, glucose-6-phosphate dehydrogenase, transketolase, transaldolase, 6-phosphogluconolactonase, fructose 1,6-biphosphatase, homoserine dehydrogenase, phophoenolpyruvate carboxykinase, succinyl-CoA synthetase, methylmalonyl-CoA mutase, provided that if aspartokinase is deregulated as gene (i) at least a second gene (i) other than aspartokinase has to be deregulated, and cultivating said microorganism. | 10-01-2009 |
| 20090281353 | Use of dimethyl disulfide for methionine production in microoragnisms - The present invention features improved processes and organisms for the production of methionine. The invention demonstrates that a ΔmetF organism or a ΔmetE AmetH organism, for example, mutants of | 11-12-2009 |
| 20090298136 | Methionine producing recombinant microorganisms - This invention relates to methionine producing recombinant microorganisms. Specifically, this invention relates to recombinant strains of | 12-03-2009 |
| 20090311756 | Microorganisms with a Reactivation System for cob(I)Alamin-Dependent Methionine Synthase - The present invention relates to microorganisms and methods for producing methionine by reactivation of the MetH enzyme. | 12-17-2009 |
| 20090325244 | METHOD OF INCREASING GENE EXPRESSION USING MODIFIED CODON USAGE - The present invention relates to a method of increasing the amount of at least one polypeptide in the host cell by expressing a modified nucleotide sequence encoding for a polypeptide in a host cell with said modified nucleotide sequence being derived from a different non-modified nucleotide sequence encoding for a polypeptide of identical amino acid sequence such that the codon usage of the modified nucleotide sequence is adjusted to the codon usage of abundant proteins in the host cell. | 12-31-2009 |
| 20100003727 | Coryneform Bacteria with Formate-THF-Synthetase and/or Glycine Cleavage Activity - The present invention relates to microorganisms, in particular | 01-07-2010 |
| 20100009416 | Process for the Preparation of L-Methionine - The present invention relates to microorganisms and processes for the efficient preparation of L-methionine. In particular, the present invention relates to processes in which the amount of serine available for the metabolism of the microorganism is increased. | 01-14-2010 |
| 20100035307 | Methionine Synthases with Reduced Product Inhibition - The present invention relates to nulceotide sequences encoding enzymatically active cobalamin-methionine synthase and functional fragments thereof being modified in comparison to the respective wild-type enzyme such that said enzymes show reduced product inhibition by methionine. The present invention also relates to polypeptides being encoded by such nucleotide sequences and host cells comprising such nucleotide sequences. Furthermore, the present invention relates to methods for producing methionine in host organisms by making use of such nucleotide sequences. | 02-11-2010 |
| 20100041107 | METHOD OF REDUCING GENE EXPRESSION USING MODIFIED CODON USAGE - The present invention is directed to a method of reducing the amount of at least one polypeptide in a host cell by expressing a nucleotide sequence encoding for the polypeptide in the host cell wherein the nucleotide sequence uses codons that are rarely used according to the codon usage of the host organism. Furthermore, the present invention relates to nucleotide sequences encoding for a polypeptide with a codon usage that has been adjusted to use codons that are only rarely used according to the codon usage of the host organism. The present invention further relates to the use of such sequences and methods for producing fine chemicals such as amino acids, sugars, lipids, oils, carbohydrates, vitamins, cofactors etc. | 02-18-2010 |
| 20100047881 | Microorganisms with Deregulated Vitamin B12 System - The present invention relates to microorganisms with improved efficiency of vitamin B12 utilization. | 02-25-2010 |
| 20100324258 | Process for the Production of Gamma-Aminobutyric Acid - The present invention relates to a novel method for the fermentative production of gamma-aminobutyric acid (GABA) by cultivating a recombinant micro-organism expressing an enzyme having a glutamate decarboxylase activity. The present invention also relates to corresponding recombinant hosts, recombinant vectors, expression cassettes and nucleic acids suitable for preparing such hosts as well as to a method for preparing polyamides making use of GABA as obtained fermentative production. | 12-23-2010 |
| 20110003963 | METHOD FOR THE PRODUCTION OF DIPICOLINATE - The present invention relates to a novel method for the fermentative production of dipicolinate by cultivating a recombinant microorganism expressing an enzyme having dipicolinate synthetase activity. The present invention also relates to corresponding recombinant hosts, recombinant vectors, expression cassettes and nucleic acids suitable for preparing such hosts as well as a method of preparing polyester or polyamide copolymers making use of dipicolinate as obtained by fermentative production. | 01-06-2011 |
