| Patent application number | Description | Published |
| 20080213240 | RAC-PK as a therapeutic agent or in diagnostics, screening method for agents and process for activating RAC-PK - The invention concerns RAC-PK and fragments thereof, as well as activators and inhibitors of RAC-PK for use as medicaments, particularly in the treatment of diseases concerned with abnormalities in processes modulated by insulin, such as cellular proliferation, insulin deficiency and/or excess blood sugar levels. Moreover, the invention provides RAC-PK for use in screening potential mimics or modulators thereof. A method for screening for agents capable of affecting the activity of GSK3 is also disclosed. The invention further provides a screening kit comprising the RAC-PK as an active principle, and a method for screening compounds which are candidate mimics or modulators of RAC-PK activity comprising detecting specific interactions between the candidate compounds and RAC-PK. There is also provided a process for activating RAC-PK comprising treatment thereof with a phosphatase inhibitor. | 09-04-2008 |
| 20080300279 | PIPERIDINE-AMIDE DERIVATIVES - The invention is concerned with novel piperidine-amide derivatives of formula (I) | 12-04-2008 |
| 20090143409 | 3-PYRIDINECARBOXAMIDE DERIVATIVES AS HDL-CHOLESTEROL RAISING AGENTS - The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula | 06-04-2009 |
| 20090270500 | 4-TRIMETHYLAMMONIO-BUTYRATES AS CPT2 INHIBITORS - This invention relates to novel 4-trimethylammoniobutyrates of the formula | 10-29-2009 |
| 20090270505 | 4-DIMETHYLAMINOBUTYRIC ACID DERIVATIVES - This invention relates to novel 4-dimethylaminobutyric acid derivatives of the formula | 10-29-2009 |
| 20100267745 | 3-Pyridinecarboxamide Derivatives as HDL-Cholesterol Raising Agents - The present invention relates to a method of raising HDL cholesterol comprising administering to a patient in need thereof a compound of the formula | 10-21-2010 |