| Patent application number | Description | Published |
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| 20100004504 | EPICARDIAL CLIP - An epicardial clip for reshaping the annulus of the mitral valve of a heart. The epicardial clip includes a curved member having an anterior segment configured to be positioned in the transverse sinus of the heart, a posterior segment configured to be positioned on the posterior side of the heart, such as on or inferior to the atrioventricular groove, and a lateral segment extending between the anterior segment and the posterior segment. The lateral segment includes a curve such that the first end of the member is positioned at or above the plane of the mitral valve and the second end of the member is positioned at or below the plane of the mitral valve. | 01-07-2010 |
| 20100137775 | DEVICE FOR DELIVERY OF REDUCED PRESSURE TO BODY SURFACES - Disclosed herein is a device which is intended to deliver and maintain reduced pressure to body surfaces for application of reduced pressure wound therapy (RPWT) also known as negative pressure wound therapy (NPWT). During application of this type of therapy, a substantially airtight seal is formed around a section of tissue to be treated. This seal is formed by a dressing which provides fluid communication from a section of tissue to a reduced pressure source. Disclosed herein is a dressing system which is configured to enhance usability and functionality of this dressing. First, the system may be configured to allow full rotation of the fluid communication conduit to the reduced pressure source along the axis substantially normal to the dressing. Second, the system may be configured to include a one-way valve to prevent backflow of any drainage fluids. Third, the system may be configured with transparent windows covered by opaque flaps to allow inspection through the dressing. Fourth, the system may be configured to include an indicator which visually makes clear whether reduced pressure is being applied or not. Fifth, the system is configured to minimize the profile of the dressing system. | 06-03-2010 |
| 20100160901 | DEVICE FOR DELIVERY OF REDUCED PRESSURE TO BODY SURFACES - Disclosed herein is a device which is intended to deliver and maintain reduced pressure to body surfaces for application of reduced pressure wound therapy (RPWT) also known as negative pressure wound therapy (NPWT). During application of this type of therapy, a substantially airtight seal is formed around a section of tissue to be treated. This seal is formed by a dressing which provides fluid communication from a section of tissue to a reduced pressure source. Disclosed herein is a dressing system which is configured to enhance usability and functionality of this dressing. First, the system may be configured to allow full rotation of the fluid communication conduit to the reduced pressure source along the axis substantially normal to the dressing. Second, the system may be configured to include a one-way valve to prevent backflow of any drainage fluids. Third, the system may be configured with transparent windows covered by opaque flaps to allow inspection through the dressing. Fourth, the system may be configured to include an indicator which visually makes clear whether reduced pressure is being applied or not. Fifth, the system is configured to minimize the profile of the dressing system. | 06-24-2010 |
| 20110137270 | PRESSURE INDICATOR - Disclosed herein is a device which is intended to deliver and maintain reduced pressure to body surfaces for application of reduced pressure wound therapy (RPWT) also known as negative pressure wound therapy (NPWT). During application of this type of therapy, a substantially airtight seal is formed around a section of tissue to be treated. This seal is formed by a dressing which provides fluid communication from a section of tissue to a reduced pressure source. Disclosed herein is a dressing system which is configured to enhance usability and functionality of this dressing. First, the system may be configured to allow full rotation of the fluid communication conduit to the reduced pressure source along the axis substantially normal to the dressing. Second, the system may be configured to include a one-way valve to prevent backflow of any drainage fluids. Third, the system may be configured with transparent windows covered by opaque flaps to allow inspection through the dressing. Fourth, the system may be configured to include an indicator which visually makes clear whether reduced pressure is being applied or not. Fifth, the system is configured to minimize the profile of the dressing system. | 06-09-2011 |
| 20120071845 | CONTROLLED NEGATIVE PRESSURE APPARATUS AND ABSORBENCY MECHANISM - Methods and devices for treatment of damaged tissue are disclosed, including treatment of wounds by employing non-electrically powered, reduced pressure therapy devices. The devices are capable of generating a substantially constant reduced pressure with low tolerance for pressure fluctuations. Also disclosed herein are reduced pressure therapy systems that comprise an alarm system to detect the depleted state of the suction device and provide an alert to the patient and/or practitioner. | 03-22-2012 |
| 20120083754 | CONTROLLED NEGATIVE PRESSURE APPARATUS AND ALARM MECHANISM - Methods and devices for treatment of damaged tissue are disclosed, including treatment of wounds by employing non-electrically powered, reduced pressure therapy devices. The devices are capable of generating a substantially constant reduced pressure with low tolerance for pressure fluctuations. Also disclosed herein are reduced pressure therapy systems that comprise an alarm system to detect the depleted state of the suction device and provide an alert to the patient and/or practitioner. | 04-05-2012 |
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| 20080260210 | TEXT CAPTURE AND PRESENTATION DEVICE - Embodiments of the invention provide devices and methods for capturing text found in a variety of sources and transforming it into a different user-accessible formats or medium. For example, the device can capture text from a magazine and provide it to the user as spoken words through headphones or speakers. Such devices are useful for individuals such as those having reading difficulties (such as dyslexia), blindness, and other visual impairments arising from diabetic retinopathy, cataracts, age-related macular degeneration (AMD), and glaucoma. | 10-23-2008 |
| 20090169061 | READING DEVICE WITH HIERARCHAL NAVIGATION - In some embodiments, disclosed is reading device that comprises a camera, at least one processor, and a user interface. The camera scans at least a portion of a document having text to generate a raster file. The processor processes the raster file to identify text blocks. The user interface allows a user to hierarchically navigate the text blocks when they are read to the user. | 07-02-2009 |
| 20090172513 | READING DEVICE WITH SHORTCUT READ FUNCTION - In some embodiments, a reading device is provided with a shortcut read mode in which a user can instruct the reading device of the type of document (e.g., invoice, package label, newspaper, etc.) that is to be read so that the device can more efficiently find and read back to the user desired (target) information from the document. | 07-02-2009 |
| 20090245695 | DEVICE WITH AUTOMATIC IMAGE CAPTURE - In some embodiments, provided are methods and reading devices with image capture capabilities for efficiently capturing multiple images. | 10-01-2009 |
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| 20080227195 | Expanding the eukaryotic genetic code - This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided. | 09-18-2008 |
| 20100160618 | Expanding the eukaryotic genetic code - This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided. | 06-24-2010 |
| 20100291559 | Compositions of orthogonal lysyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof - Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal lysyl-tRNAs, orthogonal lysyl-aminoacyl-tRNA synthetases, and orthogonal pairs of lysyl-tRNAs/synthetases, which incorporate homoglutamines into proteins are provided in response to a four base codon. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins with homoglutamines using these orthogonal pairs. | 11-18-2010 |
| 20110217733 | Expanding the eukaryotic genetic code - This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided. | 09-08-2011 |
| 20120004183 | Unnatural reactive amino acid genetic code additions - This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided. | 01-05-2012 |
| 20120129215 | Compositions of Orthogonal Lysyl-tRNA and Aminoacyl-tRNA Synthetase Pairs and Uses Thereof - Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal lysyl-tRNAs, orthogonal lysyl-aminoacyl-tRNA synthetases, and orthogonal pairs of lysyl-tRNAs/synthetases, which incorporate homoglutamines into proteins are provided in response to a four base codon. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins with homoglutamines using these orthogonal pairs. | 05-24-2012 |
| 20120135524 | Novel Nucleic Acid Constructs Containing Orthogonal Site Selective Recombinases (OSSRs) - The present invention provides for a recombinant nucleic acid comprising a nucleotide sequence comprising a plurality of constructs, wherein each construct independently comprises a nucleotide sequence of interest flanked by a pair of recombinase recognition sequences. Each pair of recombinase recognition sequences is recognized by a distinct recombinase. Optionally, each construct can, independently, further comprise one or more genes encoding a recombinase capable of recognizing the pair of recombinase recognition sequences of the construct. The recombinase can be an orthogonal (non-cross reacting), site-selective recombinase (OSSR). | 05-31-2012 |
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| 20100163057 | STERILE SURGICAL ADAPTOR - A sterile adaptor, a sterile drape with the integrated sterile adaptor, and a telerobotic surgical system including the sterile drape with a drape interface are provided. The adaptor, drape, and system allow for draping portions of a telerobotic surgical system to maintain a sterile barrier between the sterile surgical field and the non-sterile robotic system while also providing an interface for transferring mechanical and electrical energy and signals between a robotic arm and a surgical instrument in the sterile field. | 07-01-2010 |
| 20100174293 | STERILE SURGICAL ADAPTOR - A sterile drape with integrated sterile adaptor, a telerobotic surgical system, and method of use are provided for draping portions of a telerobotic surgical system to maintain a sterile barrier between the sterile surgical field and the non-sterile robotic system while also providing an interface for transferring mechanical and electrical energy and signals. | 07-08-2010 |
| 20100200002 | STERILE SURGICAL DRAPE - An improved sterile drape, system, and method for draping portions of a telerobotic surgical system are provided. In one embodiment, a sterile drape includes an exterior surface adjacent to a sterile field for performing a surgical procedure, and an interior surface forming a cavity for receiving the non-sterile portion of a robotic surgical system, such as a manipulator. The drape further includes a fastener coupled to the exterior surface for securing the sterile drape to the non-sterile portion of the robotic surgical system while reducing the volume of the sterile drape. Advantageously, the drape allows for quick and simple installation and increases visualization of the patient by reducing the size of the drape with more form fitting features, while allowing for freedom of movement of the manipulator. | 08-12-2010 |
| 20100228284 | SURGICAL TOOL HAVING POSITIVELY POSITIONABLE TENDON-ACTUATED MULTI-DISK WRIST JOINT - The present invention is directed to a tool having a wrist mechanism that provides pitch and yaw rotation in such a way that the tool has no singularity in roll, pitch, and yaw. A positively positionable multi-disk wrist mechanism includes a plurality of disks or vertebrae stacked in series. Each vertebra is configured to rotate in pitch or in yaw with respect to each neighboring vertebra. Actuation cables are used to manipulate and control movement of the vertebrae. In specific embodiments, some of the cables are distal cables that extend from a proximal vertebra through one or more intermediate vertebrae to a distal vertebra, while the remaining cables are medial cables that extend from the proximal vertebra to one or more of the intermediate vertebrae. The cables are actuated by a pivoted plate cable actuator mechanism. In specific embodiments, the actuator mechanism includes a plurality of small radius holes or grooves for receiving the medial cables and a plurality of large radius holes or grooves for receiving the distal cables. The holes or grooves restrain the medial cables to a small radius of motion and the distal cables to a large radius of motion, so that the medial cables to the medial vertebra move only a fraction of the amount as the distal cables to the distal vertebra, so as to achieve precise control and manipulation of the vertebrae. | 09-09-2010 |
| 20110028991 | Cardiac Tissue Ablation Instrument with Flexible Wrist - An articulate minimally invasive surgical instrument with a flexible wrist to facilitate the safe placement and provide visual verification of the ablation catheter or other devices in Cardiac Tissue Ablation (CTA) treatments is described. In one embodiment, the instrument is an endoscope which has an elongate shaft, a flexible wrist at the working end of the shaft, and a vision scope lens at the tip of the flexible wrist. The flexible wrist has at least one degree of freedom to provide the desired articulation. It is actuated and controlled by a drive mechanism located in the housing at the distal end of the shaft. The articulation of the endoscope allows images of hard-to-see places to be taken for use in assisting the placement of the ablation catheter on the desired cardiac tissue. The endoscope may further include couplings to releasably attach an ablation device/catheter or a catheter guide to the endoscope thereby further utilizing the endoscope articulation to facilitate placement of the ablation catheter on hard-to-reach cardiac tissues. In another embodiment, the articulate instrument is a grasper or any other instrument with a flexible wrist and a built-in lumen to allow an endoscope to insert and be guided to the distal end of the instrument. | 02-03-2011 |
| 20110118755 | Flexible Wrist for Surgical Tool - The present invention is directed to a tool having a wrist mechanism that provides pitch and yaw rotation in such a way that the tool has no singularity in roll, pitch, and yaw. In one embodiment, a minimally invasive surgical instrument comprises an elongate shaft having a working end, a proximal end, and a shaft axis between the working end and the proximal end; and an end effector. A wrist member has a flexible tube including an axis extending through an interior surrounded by a wall. The wall of the flexible tube includes a plurality of lumens oriented generally parallel to the axis of the flexible tube. The wrist member has a proximal portion connected to the working end of the elongate shaft and a distal portion connected to the end effector. A plurality of actuation cables have distal portions connected to the end effector and extend from the distal portion through the lumens of the wall of the wrist member toward the elongate shaft to proximal portions which are actuatable to bend the wrist member in pitch rotation and yaw rotation. | 05-19-2011 |
| 20110125166 | Flexible Wrist for Surgical Tool - The present invention is directed to a tool having a wrist mechanism that provides pitch and yaw rotation in such a way that the tool has no singularity in roll, pitch, and yaw. In one embodiment, a minimally invasive surgical instrument comprises an elongate shaft having a working end, a proximal end, and a shaft axis between the working end and the proximal end; and an end effector. A wrist member has a flexible tube including an axis extending through an interior surrounded by a wall. The wall of the flexible tube includes a plurality of lumens oriented generally parallel to the axis of the flexible tube. The wrist member has a proximal portion connected to the working end of the elongate shaft and a distal portion connected to the end effector. A plurality of actuation cables have distal portions connected to the end effector and extend from the distal portion through the lumens of the wall of the wrist member toward the elongate shaft to proximal portions which are actuatable to bend the wrist member in pitch rotation and yaw rotation. | 05-26-2011 |
| 20110218551 | INSTRUMENT INTERFACE OF A ROBOTIC SURGICAL SYSTEM - An instrument interface of a robotic manipulator and a surgical system including the instrument interface are provided. In one embodiment, the instrument interface includes a spring-loaded input for providing axial load and torque to a sterile adaptor capable of operably coupling an instrument. In another embodiment, a robotic surgical manipulator system includes a manipulator assembly, including a base link operably coupled to a distal end of a manipulator arm, and a carriage link movably coupled to the base link along a lengthwise axis, the carriage link including an integrated instrument interface. The system further includes an instrument operably coupled to the carriage link via the instrument interface, and a processor operably coupled to the manipulator assembly for sensing presence of the instrument. | 09-08-2011 |
| 20110277579 | Cable Re-ordering Device - A cable guide re-orders a plurality of cables. A first guide plate has a plurality of first guide holes that receive a plurality of cables in a first order. A second guide plate has a plurality of second guide holes that receive the plurality of cables in a different second order. An intermediate guide plate is located between the first and second guide plates. The intermediate guide plate has a plurality of intermediate guide holes. Each of the intermediate guide holes receives one of the plurality of cables and causes a change of direction in the cable to facilitate the change from the first to the second order. The intermediate guide plate may further include cable passages to allow some cables to pass through without changing direction. There may be more than one intermediate guide plate. The cables may change from a generally linear to a generally circular arrangement. | 11-17-2011 |
