Patent application number | Description | Published |
20080228443 | SYSTEM AND METHOD FOR BENCHMARKING CORRELATED STREAM PROCESSING SYSTEMS - A system, method, and computer program product for benchmarking a stream processing system are disclosed. The method comprises generating a plurality of correlated test streams. A semantically related data set is embedded within each of the test streams in the plurality of correlated test streams. The plurality of correlated test streams is provided to at least one stream processing system. A summary is generated for each of the semantically related embedded data sets. A common identifier, which is transparent to the system being tested, is embedded within each stream in the plurality of correlated test streams. The common identifier is extracted from the output data set generated by the stream processing system. At least one of the stored copies of the summaries and the common identifier are compared to an output data set including a set of zero or more correlation results generated by the stream processing system. | 09-18-2008 |
20080235691 | SYSTEM AND METHOD OF STREAM PROCESSING WORKFLOW COMPOSITION USING AUTOMATIC PLANNING - An automatic planning system is provided for stream processing workflow composition. End users provide requests to the automatic planning system. The requests are goal-based problems to be solved by the automatic planning system, which then generates plan graphs to form stream processing applications. A scheduler deploys and schedules the stream processing applications for execution within an operating environment. The operating environment then returns the results to the end users. | 09-25-2008 |
20090024358 | BENCHMARKING CORRELATED STREAM PROCESSING SYSTEMS - A system, method, and computer program product for benchmarking a stream processing system are disclosed. The method comprises generating a plurality of correlated test streams. A semantically related data set is embedded within each of the test streams in the plurality of correlated test streams. The plurality of correlated test streams is provided to at least one stream processing system. A summary is generated for each of the semantically related embedded data sets. A common identifier, which is transparent to the system being tested, is embedded within each stream in the plurality of correlated test streams. The common identifier is extracted from the output data set generated by the stream processing system. At least one of the stored copies of the summaries and the common identifier are compared to an output data set including a set of zero or more correlation results generated by the stream processing system. | 01-22-2009 |
20090282487 | Method of Managing and Mitigating Security Risks Through Planning - An exemplary method is provided for managing and mitigating security risks through planning. A first security-related information of a requested product is received. A second security-related information of resources that are available for producing the requested product is received. A multi-stage process with security risks managed by the first security-related information and the second security-related information is performed to produce the requested product. | 11-12-2009 |
20090327492 | TEMPLATE-BASED APPROACH FOR WORKLOAD GENERATION - A system and method for workload generation include a processor for identifying a workload model by determining each of a hierarchy for workload generation, time scales for workload generation, and states and transitions at each of the time scales, and defining a parameter by determining each of fields for user specific attributes, application specific attributes, network specific attributes, content specific attributes, and a probability distribution function for each of the attributes; a user level template unit corresponding to a relatively slow time scale in signal communication with the processor; an application level template corresponding to a relatively faster time scale in signal communication with the processor; a stream level template corresponding to a relatively fastest time scale in signal communication with the processor; and a communications adapter in signal communication with the processor for defining a workload generating unit responsive to the template units. | 12-31-2009 |
20100242120 | Mitigating and managing privacy risks using planning - System and methods are provided for managing and mitigating privacy risks in a system having a network of processing elements. According to one method, there is receive a request for at least one output product from the system. The request includes a set of privacy parameters. At least one set of workflow generating strategies are created that results in the output product having a privacy risk value below a predefined threshold. At least one of the workflow generating strategies is deployed for automatically producing the at least one output product. | 09-23-2010 |
Patent application number | Description | Published |
20100273219 | MULTI-PRIMER AMPLIFICATION METHOD FOR BARCODING OF TARGET NUCLEIC ACIDS - In certain embodiments, the present invention provides amplification methods in which nucleotide tag(s) and, optionally, a barcode nucleotide sequence are added to target nucleotide sequences. In other embodiments, the present invention provides a microfluidic device that includes a plurality of first input lines and a plurality of second input lines. The microfluidic device also includes a plurality of sets of first chambers and a plurality of sets of second chambers. Each set of first chambers is in fluid communication with one of the plurality of first input lines. Each set of second chambers is in fluid communication with one of the plurality of second input lines. The microfluidic device further includes a plurality of first pump elements in fluid communication with a first portion of the plurality of second input lines and a plurality of second pump elements in fluid communication with a second portion of the plurality of second input lines. | 10-28-2010 |
20130005585 | NUCLEIC ACID ENCODING REACTIONS - Described herein are methods useful for incorporating one or more adaptors and/or nucleotide tag(s) and/or barcode nucleotide sequence(s) one, or typically more, target nucleotide sequences. In particular embodiments, nucleic acid fragments having adaptors, e.g., suitable for use in high-throughput DNA sequencing are generated. In other embodiments, information about a reaction mixture is encoded into a reaction product. Also described herein are methods and kits useful for amplifying one or more target nucleic acids in preparation for applications such as bidirectional nucleic acid sequencing. In particular embodiments, methods of the invention entail additionally carrying out bidirectional DNA sequencing. Also described herein are methods for encoding and detecting and/or quantifying alleles by primer extension. | 01-03-2013 |
20130323732 | SINGLE-PARTICLE ANALYSIS OF PARTICLE POPULATIONS - In certain embodiments, the invention provides methods and devices for assaying single particles in a population of particles, wherein at least two parameters are measured for each particle. One or more parameters can be measured while the particles are in the separate reaction volumes. Alternatively or in addition, one or more parameters can be measured in a later analytic step, e.g., where reactions are carried out in the separate reaction volumes and the reaction products are recovered and analyzed. In particular embodiments, one or more parameter measurements are carried out “in parallel,” i.e., essentially simultaneously in the separate reaction volumes. | 12-05-2013 |
20140272952 | MULTI-PRIMER AMPLIFICATION METHOD FOR BARCODING OF TARGET NUCLEIC ACIDS - In certain embodiments, the present invention provides amplification methods in which nucleotide tag(s) and, optionally, a barcode nucleotide sequence are added to target nucleotide sequences. In other embodiments, the present invention provides a microfluidic device that includes a plurality of first input lines and a plurality of second input lines. The microfluidic device also includes a plurality of sets of first chambers and a plurality of sets of second chambers. Each set of first chambers is in fluid communication with one of the plurality of first input lines. Each set of second chambers is in fluid communication with one of the plurality of second input lines. The microfluidic device further includes a plurality of first pump elements in fluid communication with a first portion of the plurality of second input lines and a plurality of second pump elements in fluid communication with a second portion of the plurality of second input lines. | 09-18-2014 |
Patent application number | Description | Published |
20080217254 | Magnetic Bead Trap and Mass Spectrometer Interface - A device and method for capture of magnetic beads in a rotary magnetic bead trap is disclosed. The device allows capture, washing, elution and ejection of beads in an automated system. Analyte is eluted in a small volume in a capillary-scale fluid system compatible with LC-MS/MS analysis. | 09-11-2008 |
20140017716 | PROTEOLYTIC DIGESTION KIT WITH DRIED REAGENTS - Compositions and methods are provided for the rapid and efficient denaturation and degradation of protein samples. The compositions and methods produce samples that can readily be analyzed by, for example, mass spectrometry. Unwanted dilution of the sample is avoided and the samples and methods are amenable for use with robotic laboratory sample handling instruments. The compositions and methods surprisingly provide significantly improved reproducibility and accuracy of the resulting mass spectrometric analyses. | 01-16-2014 |
20140120549 | HIGH SENSITIVITY QUANTITATION OF PEPTIDES BY MASS SPECTROMETRY - The instant invention provides an economical flow-through method for determining amount of target proteins in a sample. An antibody preparation (whether polyclonal or monoclonal, or any equivalent specific binding agent) is used to capture and thus enrich a specific monitor peptide (a specific peptide fragment of a protein to be quantitated in a proteolytic digest of a complex protein sample) and an internal standard peptide (the same chemical structure but including stable isotope labels). Upon elution into a suitable mass spectrometer, the natural (sample derived) and internal standard (isotope labeled) peptides are quantitated, and their measured abundance ratio used to calculate the abundance of the monitor peptide, and its parent protein, in the initial sample. | 05-01-2014 |