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Andersen, Naerum

Jens Toenne Andersen, Naerum DK

Patent application numberDescriptionPublished
20090317865Eubacterial RNA-Polymerase Mutants With Altered Product Production - The present invention relates to an isolated mutant eubacterium comprising at least one mutation resulting in a substitution of at least one amino acid in the beta-subunit of the RNA-polymerase encoded for by the rpoB-gene providing an altered production of a product of interest when said production of a product of interest is compared to the production of the same product in an isogenic wild type strain grown at identical conditions, wherein the substitution of at least one amino acid occurs at any of positions 469, 478, 482, 485, or 487 of SEQ ID NO:2, or at the equivalent positions in any eubacterial RNA-polymererase beta-subunit family member. Another aspect of the invention relates to a process for producing at least one product of interest in a mutant eubacterium and to a use of the mutant eubacterium according to the invention for producing at least one product of interest.12-24-2009

Jens Tonne Andersen, Naerum DK

Patent application numberDescriptionPublished
20090176290Bacillus Host Cell07-09-2009
20090203074Bacillus Host Cell08-13-2009
20090275104Bacillus licheniformis chromosone - The present invention relates to an isolated polynucleotide of the complete chromosome of 11-05-2009

Patent applications by Jens Tonne Andersen, Naerum DK

Jens Tønne Andersen, Naerum DK

Patent application numberDescriptionPublished
20110086407Bacillus licheniformis chromosome - The present invention relates to an isolated polynucleotide of the complete chromosome of 04-14-2011

Mads Hald Andersen, Naerum DK

Patent application numberDescriptionPublished
20110002954RHOC-BASED IMMUNOTHERAPY - The present invention relates generally to the field of prophylaxis and therapy of metastatic cancer. In particular there is provided a protein; Ras Homology gene family, member C (RhoC) or peptide fragments thereof that are capable of eliciting anti-cancer immune responses. Specifically, the invention relates to use of RhoC or peptides derived thereof or RhoC specific T-cells for treatment of metastatic cancer. Hence, the invention in one aspect relates to RhoC specific T-cells adoptively transferred or induced in vivo by vaccination as a treatment of cancer. Also the use of RhoC and immunogenic peptide fragments hereof in cancer treatment, diagnosis and prognosis is provided.01-06-2011
20110091489SURVIVIN PEPTIDE VACCINE - The present invention relates to a therapeutic vaccine comprising one or more survivin polypeptide fragments. The vaccine can be used for prophylactic, ameliorating and/or curative treatment of e.g. cancer diseases. The invention further relates to methods of combination treatment.04-21-2011
20110318372INDOLEAMINE 2,3-DIOXYGENASE BASED IMMUNOTHERAPY - The present invention relates to the field of prophylaxis and therapy of cancer. In particular there is provided a protein Indoleamine 2,3-dioxygenase (IDO) or peptide fragments here of that are capable of eliciting anti-cancer immune responses. Specifically, the invention relates to the use of DO or peptides derived here from or IDO specific T-cells for treatment of cancer. The invention thus relates to an anti-cancer vaccine which optionally may be used in combination with other immunotherapies and to IDO specific T-cells adoptively transferred or induced in vivo by vaccination as a treatment of cancer. It is an aspect of the invention that the medicaments herein provided may be used in combination with cancer chemotherapy treatment. A further aspect relates to the prophylaxis and therapy of infections by the same means as described above. The use of IDO and immunogenic peptide fragments hereof in cancer and infection treatment, diagnosis and prognosis is also provided.12-29-2011