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Amara, US

Ashok Babu Amara, Mountain View, CA US

Patent application numberDescriptionPublished
20090157898Generic Format for Efficient Transfer of Data - Methods, systems and apparatus, including computer program products, for transferring, receiving, and storing multiple element data in a string of characters. Multiple data elements are sent in a string of delimited characters and have respective project identifiers, data types, and index numbers used to extract and store the data elements at a receiving computer.06-18-2009
20110307515Conversion Path Performance Measures And Reports - Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for providing conversion path performance measures and reports. In one aspect, user interaction data are obtained, were the user interaction data specify user interactions for a plurality of conversions. User interactions that are associated with each conversion are selected from the user interaction data, where the associated user interactions for each conversion are user interactions with a converting user during the conversion cycle for the conversion. Using the user interaction data for the selected user interactions, a quantity of user interactions that are associated with each conversion and occurred during the conversion cycle for the conversion are determined. In turn, conversion path performance measures are computed and reports specifying the conversion path performance measures are generated.12-15-2011

John Amara, Reading, MA US

Patent application numberDescriptionPublished
20120029176Chromatography Media And Method - Adsorptive media for chromatography, particularly ion-exchange chromatography, derived from a shaped fiber. In certain embodiments, the functionalized shaped fiber presents a fibrillated or ridged structure which greatly increases the surface area of the fibers when compared to ordinary fibers. Also disclosed herein is a method to add surface pendant functional groups that provides cation-exchange or anion-exchange functionality to the high surface area fibers. This pendant functionality is useful for the ion-exchange chromatographic purification of biomolecules, such as monoclonal antibodies (mAbs).02-02-2012

John P. Amara, Reading, MA US

Patent application numberDescriptionPublished
20100297556Coating compositions suitable for use with an overcoated photoresist - Organic coating compositions, particularly antireflective coating compositions, are provided that comprise that comprise a diene/dienophile reaction product. Preferred compositions of the invention are useful to reduce reflection of exposing radiation from a substrate back into an overcoated photoresist layer and/or function as a planarizing, conformal or via-fill layer.11-25-2010
20100297557Coating compositions suitable for use with an overcoated photoresist - Organic coating compositions, particularly antireflective coating compositions, are provided that can be developed with an aqueous alkaline developer, including in a single step during development of an overcoated photoresist layer. Preferred coating compositions comprise a tetrapolymer that comprises at least four distinct functional groups.11-25-2010
20110003250COATING COMPOSITIONS SUITABLE FOR USE WITH AN OVERCOATED PHOTORESIST - In one aspect, organic coating compositions, particularly antireflective coating compositions, are provided that comprise that comprise a diene/dienophile reaction product. In another aspect, organic coating compositions, particularly antireflective coating compositions, are provided that comprise a component comprising a hydroxyl-naphthoic group, such as a 6-hydroxy-2-naphthoic group Preferred compositions of the invention are useful to reduce reflection of exposing radiation from a substrate back into an overcoated photoresist layer and/or function as a planarizing, conformal or via-fill layer.01-06-2011

John P. Amara, Charlestown, MA US

Patent application numberDescriptionPublished
20090148789Coating compositions for use with an overcoated photoresist - In one aspect, the invention relates to silicon-containing organic coating compositions, particularly antireflective coating compositions, that contain a repeat unit wherein chromophore moieties such as phenyl are spaced from Si atom(s). In another aspect, silicon-containing underlayer compositions are provided that are formulated as a liquid (organic solvent) composition, where at least one solvent of the solvent component comprise hydroxy groups.06-11-2009
20100063225Polymer synthetic technique - The present invention generally relates to methods for the synthesis of species including monomers and polymers. Methods of the invention comprise the use of chemical techniques including metathesis chemistry to synthesize, for example, monomers and/or polymers with desired functional groups.03-11-2010

Patent applications by John P. Amara, Charlestown, MA US

Rama Amara, Atlanta, GA US

Patent application numberDescriptionPublished
20100040614COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFECTIONS AND TUMORS - PD-1 antagonists are disclosed that can be used to reduce the expression or activity of PD-1 in a subject. An immune response specific to an infectious agent or to tumor cells can be enhanced using these PD-1 antagonists in conjunction with an antigen from the infectious agent or tumor. Thus, subjects with infections, such as persistent infections can be treated using PD-1 antagonists. In addition, subjects with tumors can be treated using the PD-1 antagonists. In several examples, subjects can be treated by transplanting a therapeutically effective amount of activated T cells that recognize an antigen of interest and by administering a therapeutically effective amount of a PD-1 antagonist.02-18-2010

Rama Amara, Decatur, GA US

Patent application numberDescriptionPublished
20100151492METHODS FOR THE TREATMENT OF INFECTIONS AND TUMORS - PD-1 antagonists are disclosed that can be used to reduce the expression or activity of PD-1 in a subject. An immune response specific to an infectious agent or to tumor cells can be enhanced using these PD-1 antagonists in conjunction with an antigen from the infectious agent or tumor. Thus, subjects with infections, such as persistent infections can be treated using PD-1 antagonists. In addition, subjects with tumors can be treated using the PD-1 antagonists. In several examples, subjects can be treated by transplanting a therapeutically effective amount of activated T cells that recognize an antigen of interest and by administering a therapeutically effective amount of a PD-1 antagonist. Methods are also disclosed for determining the efficacy of a PD-1 antagonist in a subject administered the PD-1 antagonist. In some embodiments, these methods include measuring proliferation of memory B cells in a sample from a subject administered the PD-1 antagonist.06-17-2010

Rama Rao Amara, Decatur, GA US

Patent application numberDescriptionPublished
20120076820CD40L VACCINES, COMPOSITIONS, AND METHODS RELATED THERETO - The disclosure relates to vaccinating a subject against a viral infection, compositions, and methods related thereto. In certain embodiments, the disclosure relates to the use of CD40L expressed on viral like particle as an adjuvant, in combination with a viral antigen, to vaccinate a subject.03-29-2012

Ryan Amara, Tewksbury, MA US

Patent application numberDescriptionPublished
20100198040Methods and apparatus for assessing and improving electrode contact with cardiac tissue - Embodiments of the invention relate to methods for assessing and/or improving contact between an electrophysiology catheter and tissue, and catheters for performing the methods. One embodiment relates to a catheter comprising a braided conductive member coupled to the distal end of a shaft, wherein the braided conductive member comprises a plurality of pressure sensitive wires. Another embodiment relates to a catheter comprising a braided conductive member having a plurality of sectors and coupled to the distal end of a shaft, and a balloon assembly constructed and arranged to selectively apply distal pressure to one or more sectors of the braided conductive member.08-05-2010