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Amar, US

Anshul Amar, Los Angeles, CA US

Patent application numberDescriptionPublished
20090313194METHODS AND APPARATUS FOR AUTOMATED IMAGE CLASSIFICATION - A system for automated classification of an image of an electronic document such as a facsimile document. The image is converted to a textual representation, and at least some of the terms in the textual representation may be associated with one or more predefined classification types, thereby enabling the document to be classified, and for multi-page documents, determining boundaries used to split the document into sections. The development of associations between terms and classification types may result from providing, to the system, a training set of manually-classified documents. A training module analyzes the training set to calculate probabilities that particular terms may appear in documents of a particular classification type. Probabilities established during training are used during automated document processing to assign a classification type to the document. A confidence score associated with the assigned classification type provides a metric for assessing the accuracy of the automated process.12-17-2009

Anshul Amar, Cambridge, MA US

Patent application numberDescriptionPublished
20090192821Medical image annotation - Incorporating new technology into an existing medical practice is often difficult. Documents associated with a patient, for example, a patient's medical charts, are typically provided physically, i.e., as “hard copies,” when a patient is being serviced by multiple health care providers Disclosed are means for electronically annotating an image associated with a patient workflow. In one implementation, there is a method that includes receiving an image via a communications network, presenting the image to a user, and capturing an annotation made to the image by the user. The annotations and the image to a medical practice management server via the communications network and the annotated image is stored as part of a patient medical record.07-30-2009

Marcele J.a. Amar, Gaithersburg, MD US

Patent application numberDescriptionPublished
20090270331MULTI-DOMAIN AMPHIPATHIC HELICAL PEPTIDES AND METHODS OF THEIR USE - Disclosed herein are peptides or peptide analogs with multiple amphipathic α-helical domains that promote lipid efflux from cells via an ABCA1-dependent pathway. Also provided herein are methods of using multi-domain amphipathic α-helical peptides or peptide analogs to treat or inhibit dyslipidemic disorders. Methods for identifying non-cytotoxic peptides that promote ABCA1-dependent lipid efflux from cells are also disclosed herein.10-29-2009
20100203099MULTI-DOMAIN AMPHIPATHIC HELICAL PEPTIDES AND METHODS OF THEIR USE - Disclosed herein are peptides or peptide analogs with multiple amphipathic α-helical domains that promote lipid efflux from cells via an ABCA1-dependent pathway. Also provided herein are methods of using multi-domain amphipathic α-helical peptides or peptide analogs to treat or inhibit dyslipidemic disorders. Methods for identifying non-cytotoxic peptides that promote ABCA1-dependent lipid efflux from cells are also disclosed herein.08-12-2010

Marcelo J.a. Amar, Gaithersburg, MD US

Patent application numberDescriptionPublished
20110033518PEPTIDES PROMOTING LIPID EFFLUX VIA ABCA1 AND ACTIVATING A LIPOPROTEIN LIPASE - Disclosed herein are peptides and peptide analogs with multiple amphipathic α-helical domains that promote lipid efflux from cells via an ABCA1-dependent pathway, as well as peptides that activate lipoprotein lipase, and compositions comprising such peptides or combinations thereof. Also provided herein are methods of using multi-domain amphipathic α-helical peptides or peptide analogs to treat or inhibit dyslipidemic disorders. Methods for identifying non-cytotoxic peptides that promote ABCA1-dependent lipid efflux from cells and activate lipoprotein lipase within cells are also disclosed herein.02-10-2011

Salomon Amar, Brookline, MA US

Patent application numberDescriptionPublished
20090062190Transcriptional Regulation of Cytokines by LITAF and STAT (6)(B) - The present invention relates to novel proteins (LITAF and STAT6(B)) and the nucleotide sequences encoding the same. The present invention also relates to the use of the novel peptides and nucleotide sequences of the present invention, or functional fragments thereof, for the regulation of cytokine expression. The present invention also relates to the use of the novel proteins and nucleotides sequences of the present invention for the regulation of inflammatory responses in mammals including the regulation of angiogenesis and tubulogenesis. Also in this regard, the present invention relates to the generation of null mutant animals deficient in the expression of one or both of the proteins of the present invention.03-05-2009
20090215049NOVEL LITAF BINDING SITE PEPTIDES AND METHODS OF USING THE SAME - The invention provides molecules containing nucleic acid sequences for fragments of LPS-induced TNF-α factor (LITAF) and vectors containing these sequences. Also provided are molecules that contain the peptide sequence SQTWREPGAAGSPFHL, or homologs thereof. Such molecules may be useful in the treatment of diseases that relate to the expression of TNF-α, where treatment involves the modulation of this expression. The invention also provides methods for identifying compounds that inhibit or enhance the transcription of TNF-α.08-27-2009
20110053849REGULATION OF LITAF MODULATED CYTOKINE PRODUCTION BY A NOVEL P53 SHORT PEPTIDE - The present invention relates to a novel isolated and purified peptide of the sequence KQSQHMT [SEQ ID NO: 1], nucleic acid sequences encoding said peptide sequence and capable of expressing said sequence as an exogenous protein in a target cell; as well as methods for the reduction or inhibition of LITAF activity by transfecting the peptide KQSQHMT [SEQ ID NO: 1] or a nucleic acid capable of expressing said peptide, into a target cell. The present invention also relates to the use of the novel peptide (and corresponding nucleotide sequences) of the present invention for the regulation of cytokine expression in target cells. The present invention also relates to the use of the novel peptide (and corresponding nucleotide sequences) of the present invention for the regulation of inflammatory responses in mammals.03-03-2011
20110288035PIMAP39 MODULATES INFLAMMATORY RESPONSE - The present invention relates to a novel peptide sequence named PIMAP39 (herein referred to as SEQ ID NO.: 1) and methods of use of the novel sequence and functional variants thereof. The present invention also relates to methods for reducing and/or modulating inflammatory responses by administration of the peptide of the present invention. Furthermore, the present invention relates to the modulation of the expression of cytokines effected as part of an inflammatory response by administration of the peptide of the present invention.11-24-2011

Shaoul Amar, Los Angeles, CA US

Patent application numberDescriptionPublished
20120072501System and Method Providing Universal Addressing in Digital Communication Systems - A system, method and computer program product providing a universal naming system.03-22-2012