Patent application number | Description | Published |
20120070383 | POLYMERIC NANO-CARRIERS WITH A LINEAR DUAL RESPONSE MECHANISM AND USES THEREOF - The present invention features compositions in which nano-carriers are synthesized with polymers that respond to lower pH and/or ROS by being degraded. The compositions may be utilized to selectively deliver payloads within patients by responding to lower pH and/or ROS at localities within the patient. The present invention also features methods of synthesizing nano-carriers that are degraded by lower pH and/or ROS. | 03-22-2012 |
20120259267 | Chemically Amplified Response Strategies for Medical Sciences - Compositions are provided in which dendrimers and/or nanoparticles are synthesized with multi-photon responsive elements and self-immolative oligomers. The compositions may be utilized to selectively deliver Payloads within tissue by irradiating the compositions. The compositions may also be used to amplify sensitivity to irradiation. | 10-11-2012 |
20130234372 | SINGLE STEP POLYMERIZATION OF COVALENTLY BOUND MULTILAYER MATRICES - A method is provided for forming complex tissue using density gradient multilayer polymerization (DGMP) to form strong hydrogels with smooth transitions between layers. The multicompartment hydrogel is formed by co-dissolving a polymer precurser with a constituent in multiple solvent fractions to a create prepolymer solutions with different densities, layering the prepolymer solutions on top of each other from high to low solvent density, and irradiating the prepolymer solutions to form a polymer. The hydrogels may be used as biomimetic matrices. | 09-12-2013 |
20140255311 | BIOCOMPATIBLE POLYMERIC NANOPARTICLES DEGRADE AND RELEASE CARGO IN RESPONSE TO BIOLOGICALLY RELEVANT LEVELS OF HYDROGEN PEROXIDE - Disclosed are compositions and synthesis methods that pertain to biocompatible polymeric capsules capable of undergoing backbone degradation and cargo release upon exposure to biologically relevant concentrations of hydrogen peroxide (50-100 μM of H | 09-11-2014 |
20140358068 | SELECTIVE LIPOLYSIS USING NIR LIGHT AND NANOPARTICLES - A system and method are provided for minimally-invasive lipolysis in a target area by injecting the area with a solution of photo-absorbing nanoparticles and irradiating the injected area with a beam of near infrared (NIR) light. The NIR emission wavelength excites the nanoparticles to melt fat within the target area so that the liquefied fat can be aspirated from the target area. The nanoparticles may be gold nanorods having aspect ratios selected to produce surface plasmon resonance when irradiated with NIR light around 800 nm. | 12-04-2014 |
20150018812 | FINE SPATIOTEMPORAL CONTROL OF THERMOLYSIS AND LIPOLYSIS USING NIR LIGHT - A system and method are provided for minimally-invasive lipolysis in a target area by injecting the area with a solution of photo-absorbing nanoparticles and irradiating the injected area with a beam of near infrared (NIR) light. The NIR emission wavelength is adapted to excite the nanoparticles to melt fat within the target area so that the liquefied fat can be aspirated from the target area. The nanoparticles may be gold nanorods having aspect ratios selected to produce surface plasmon resonance when irradiated with NIR light around 800 nm. | 01-15-2015 |
20150056181 | NANOCARRIERS WITH MULTI-PHOTON RESPONSE ELEMENTS - Compositions are provided in which dendrimers and/or nanoparticles are synthesized with multi-photon responsive elements and self-immolative oligomers. The compositions may be utilized to selectively deliver Payloads within tissue by irradiating the compositions. The compositions may also be used to amplify sensitivity to irradiation. | 02-26-2015 |
20150079005 | POLYMERIC NANOCARRIERS WITH LINEAR DUAL RESPONSE MECHANISM - Nanocarriers are synthesized with polymers that respond to lower pH and/or ROS by being degraded. The compositions may be utilized to selectively deliver payloads within patients by responding to lower pH and/or ROS at localities within the patient. The present invention also features methods of synthesizing nanocarriers that are degraded by lower pH and/or ROS. | 03-19-2015 |
20150119792 | LIGHT DEGRADABLE DRUG DELIVERY SYSTEM FOR OCULAR THERAPY - A system and method for delivering a payload to ocular tissue includes a solution of light-degradable nanoparticles encapsulating the payload. The solution may be introduced to the ocular tissue by way of injection or through a contact lens into which the solution is embedded. A light source delivers a beam of light to the ocular tissue at the location where the solution was introduced to initiate breakdown of the particles, releasing the payload. The light source may be a laser, LED, LCD or arc lamp emitting in the ultraviolet light range. | 04-30-2015 |
20150258195 | POLYMERIC NANOCARRIERS WITH LIGHT-TRIGGERED RELEASE MECHANISM - Near infrared radiation at a wavelength that induces resonance in water is used to remotely activate thermal plasticization of polymeric particles to trigger the release of encapsulated molecules from the particles. Nanocarriers formed from biocompatible hydrophilic polymers may be used to deliver encapsulated molecules to tissue with a reversible transition that allows repeated activations for extended release of the payload. | 09-17-2015 |
Patent application number | Description | Published |
20120091203 | METHOD OF ENCODING AND DECODING TEXT ON A MATRIX CODE SYMBOL - The present invention provides method of encoding and decoding text on a matrix code symbol. A method of encoding text on a matrix code symbol includes; receiving a predefined encoding value associated with each of one or more characters of the plurality of characters and modifying the predefined encoding value associated with each of the one or more characters to obtain a corresponding modified encoding value. Thereafter, the one or more characters are encoded on the matrix code symbol using the corresponding modified encoding value. Further, the method of decoding the text on the matrix code symbol includes; retrieving one or more encoded values from the matrix code symbol and mapping each of one or more modified encoded values in the one or more encoded values with a corresponding predefined encoded value. Thereafter, the corresponding predefined encoded value is decoded to determine a corresponding character. | 04-19-2012 |
20120091205 | APPARATUS AND METHOD FOR DECODING MATRIX CODE SYMBOL - An apparatus and method for decoding a matrix code symbol is disclosed. The apparatus includes an image processor configured to process an image corresponding to the matrix code symbol. The apparatus further includes a decoder configured to retrieve one or more encoded values from the matrix code symbol in response to the processing of the image corresponding to the matrix code symbol. The one or more encoded value includes one or more modified encoded values. The decoder is further configured to map each of the one or more modified encoded values with a corresponding predefined encoded value. A modified encoded value includes two or more digits of a corresponding predefined encoded value. The corresponding predefined encoded value is decoded by the decoder to determine a corresponding character. | 04-19-2012 |
20120193424 | METHOD OF ENCODING AND DECODING DATA ON A MATRIX CODE SYMBOL - The invention provides a method of encoding and decoding data on a matrix code symbol. The method of encoding data on a matrix code symbol includes receiving the data in the form of a table of data elements and converting the table of data elements into a string of characters. Thereafter, the string of characters is encoded on the matrix code symbol. Further, the method of decoding data from the matrix code symbol includes retrieving a string of characters from the matrix code symbol and converting the string of characters into a table of data elements representing the data. | 08-02-2012 |
20140124572 | SYSTEM AND METHODS FOR ENCODING AND DECODING MULTI-LINGUAL TEXT IN A MATRIX CODE SYMBOL - A method for encoding a multi-lingual text in a matrix code symbol includes receiving a multi-lingual text comprising Latin-based characters in a Latin-based language and non-Latin-based characters in a non-Latin-based language, converting the non-Latin-based characters in the multi-lingual text to index values to produce a pseudo text, and encoding the pseudo text in a matrix-code symbol. The conversion is based on a predefined mapping that converts the Unicode values of the non-Latin-based characters to index values having fewer digits than the corresponding Unicode values of the non-Latin-based characters. | 05-08-2014 |