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Almond, US
Brian D. Almond, Fitchburg, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20090191622 | SYNTHETIC NUCLEIC ACIDS FROM AQUATIC SPECIES - A synthetic nucleic acid molecule is provided that includes nucleotides of a coding region for a fluorescent polypeptide having a codon composition differing at more than 25% of the codons from a parent nucleic acid sequence encoding a fluorescent polypeptide. The synthetic nucleic acid molecule has at least 3-fold fewer transcription regulatory sequences relative to the average number of such sequences in the parent nucleic acid sequence. The polypeptide encoded by the synthetic nucleic acid molecule preferably has at least 85% sequence identity to the polypeptide encoded by the parent nucleic acid sequence. | 07-30-2009 |
Bruce Almond, Phoenix, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20100187119 | COLD SPRAY AND ANODIZATION REPAIR PROCESS FOR RESTORING WORN ALUMINUM PARTS - A method for repairing an aluminum part having a worn portion is provided. In one embodiment, the method includes the steps of: (i) producing a first substantially non-porous coating over the worn portion utilizing a cold spray process wherein a powder mixture is propelled against the worn portion of the aluminum part, and (ii) anodizing the aluminum part to grow an aluminum oxide layer overlaying the first substantially non-porous coating. The powder mixture includes aluminum and an alloy media. | 07-29-2010 |
Jennifer Lee Almond, Raleigh, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090126043 | GENERATION OF PLANTS WITH IMPROVED PATHOGEN RESISTANCE AND DROUGHT TOLERANCE - The present invention is directed to plants that display a pathogen resistance and increased drought tolerance phenotype due to altered expression of a PRDT1 nucleic acid. The invention is further directed to methods of generating plants with a pathogen resistance and increased drought tolerance phenotype. | 05-14-2009 |
Merrick Almond, Apex, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100297079 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTION - The present invention describes compounds of formulae I and II and methods for treating viral infection, such as Flaviviridae virus infection, including Hepatitis C infection (HCV). | 11-25-2010 |
Merrick R. Almond, Apex, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100249056 | Metabolically Stable Alkoxyalkyl Esters of Antiviral or Antiproliferative Phosphonates, Nucleoside Phosphonates and Nucleoside Phosphates - The present invention relates to phosphonate, nucleoside phosphonate or nucleoside phosphate compounds, compositions containing them, processes for obtaining them, and their use in treating a variety of medical disorders, in particular viral infections, cancers and the like. | 09-30-2010 |
| 20110015149 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS AND OTHER MEDICAL DISORDERS - The present application provides methods and compositions for improving the bioavailability of a lipid-containing antiviral compound, and in particular, an antiviral lipid-containing compound. In one embodiment, pharmaceutically acceptable compositions are provided that include an antiviral lipid-containing compound, or salt, ester, or prodrug thereof and one or more bioavailability enhancing compounds, such as inhibitors of cytochrome P450 enzymes. | 01-20-2011 |
| 20110021464 | METHODS OF TREATING VIRAL INFECTIONS - The present invention provides methods of treating human immunodeficiency virus (HIV) and/or hepatitis B virus (HBV) infection, including administering a compound described in the invention in an amount effective treat the HIV and/or HBV infection and at least substantially inhibit the development of resistance to said antiviral compounds in the subject. Pharmaceutical compositions are also provided. | 01-27-2011 |
| 20110130559 | Methods to Manufacture 1,3-Dioxolane Nucleosides - This application provides a process for preparing enantiomerically pure β-D-dioxolane nucleosides. In particular, a new synthesis of (−)-DAPD, suitable for large scale development, is described. In one embodiment the invention provides a process for preparing a substantially pure β-D- or β-L-1,3-dioxolane nucleosides comprising a) preparing or obtaining an esterified 2,2-dialkoxy ethanol; b) cyclizing the esterified 2,2-dialkoxy ethanol with glycolic acid to obtain a 1,3-dioxolane lactone; c) resolving the 1,3-dioxolane lactone to obtain a substantially pure D- or L-lactone; d) selectively reducing and activating the D- or L-chiral lactone to obtain a substantially pure D- or L-1,3-dioxolane; e) coupling the D- or L-1,3-dioxolane to an activated and/or protected purine or pyrimidine base; and f) optionally purifying the nucleoside to obtain a substantially pure protected β-D- or β-L-1,3-dioxolane nucleoside. | 06-02-2011 |
Michael Almond, Boulder Creek, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110314532 | IDENTITY PROVIDER SERVER CONFIGURED TO VALIDATE AUTHENTICATION REQUESTS FROM IDENTITY BROKER - Techniques are disclosed for an identity broker to authenticate users to a network device, system, or hosted application that uses certain legacy protocols for user authentication. For example, the identity broker may be configured to respond to a user authentication request from a network device formatted as a RADIUS or LDAP message. The identity broker may operate in conjunction with an identity provider to authenticate a user requesting access to a computing resource (e.g., to the network device, system, or hosted application). | 12-22-2011 |
| 20110314533 | IDENTITY BROKER CONFIGURED TO AUTHENTICATE USERS TO HOST SERVICES - Techniques are disclosed for an identity broker to authenticate users to a network device, system, or hosted application that uses certain legacy protocols for user authentication. For example, the identity broker may be configured to respond to a user authentication request from a network device formatted as a RADIUS or LDAP message. The identity broker may operate in conjunction with an identity provider to authenticate a user requesting access to a computing resource (e.g., to the network device, system, or hosted application). | 12-22-2011 |
Stephen W. Almond, Spring, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110062085 | Method of Removing Metal Contaminants from High-Density Brines - A method for the removal of soluble metal ion contamination from fluids is disclosed. The method includes passing the contaminated fluid through a filter medium comprising a reducing metal and a filter aid, such as diatomaceous earth, and collecting a filtrate with lower concentration of soluble metal ion contamination. The reducing metal can have a reduction potential of from −0.50 volt to −3.10 volt and can be capable of reducing the soluble metal ions to insoluble metal, which can then be entrapped in the filter medium or otherwise separated. | 03-17-2011 |