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Almagro, US

Irving Almagro, Irvine, CA US

Patent application numberDescriptionPublished
20100135504Foldable wireless voice muffling device for mobile communications - A handheld foldable voice-muffling device using passive noise silencing materials to dampen noise and a microphonic transceiver to transmit a user's speech and receive incoming signals allowing him to wirelessly communicate with another person or other communication devices without causing a disturbance to others in his surrounding area.06-03-2010
20100169073Foldable Wireless Device for Language Translation - A foldable handheld communication device with a clamshell housing which when used is unfolded to cover the mouth area of a user wherein such arrangement allows said device to be portable and be stored in a pocket or purse. Said device comprises a microphone to capture speech, a transceiver to transmit and receive signals, and a loudspeaker to deliver a received translated speech to a person other than said user.07-01-2010
20100185432Headset Wireless Noise Reduced Device for Language Translation - A wireless hands-free language translation device in accordance to a headset configuration which when used swivels said device inwards to cover the mouth area of a user wherein such arrangement prevents the person spoken to from hearing most of the user's voice. Said device comprises a microphone to capture speech, a transceiver to transmit and receive signals, and a loudspeaker to deliver a received translated speech to a person other than said user.07-22-2010
20100250231Mouthpiece with sound reducer to enhance language translation - A language translation device having a contour shaped housing that covers the mouth area of a user thereby substantially preventing said user's speech from being heard by a person who speaks a different language thus enhancing realtime speech-to-speech interpretation. Said device comprises a microphone to capture a user's speech that is transmitted to a language processing system and a loudspeaker to output a received translated speech for said different language person to hear.09-30-2010

Juan C. Almagro, Radnor, PA US

Patent application numberDescriptionPublished
20100021477DESIGN AND GENERATION OF HUMAN DE NOVO pIX PHAGE DISPLAY LIBRARIES - Described and claimed herein are combinatorial synthetic Fab libraries displayed on a phage pIX protein. The libraries were built on scaffolds representing the most frequently used genes in human antibodies, which were diversified to mirror the variability of natural antibodies. After selection using a diverse panel of proteins, numerous specific and high-affinity Fabs were isolated. By a process called in-line maturation the affinity of some antibodies was improved up to one hundred-fold yielding low pM binders suitable for in vivo use. This work thus demonstrates the feasibility of displaying complex Fab libraries as pIX-fusion proteins for antibody discovery and lays the foundations for studies on the structure-function relationship of antibodies.01-28-2010
20100111959ENGINEERED ANTI-IL-13 ANTIBODIES, COMPOSITIONS, METHODS AND USES - The present invention relates to engineered antibodies immunospecific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications.05-06-2010

Juan C. Almagro, Haverford, PA US

Patent application numberDescriptionPublished
20090155850Horse:Human Chimeric Antibodies - The present invention provides a plurality of chimeric single chain variable region (scFv) antibodies. The chimeric scFv antibodies individually comprise variable regions from both horse and non-horse antibodies. Methods of making and using the plurality are also provided.06-18-2009

Juan Carlos Almagro, Radnor, PA US

Patent application numberDescriptionPublished
20100261620Methods of Humanizing and Affinity-Maturing Antibodies - Methods of humanizing and affinity-maturing antibodies are disclosed.10-14-2010
20110092372Methods of Affinity Maturing Antibodies - The invention relates to methods of affinity maturing antibodies.04-21-2011

Rafael Almagro, Miami, FL US

Patent application numberDescriptionPublished
20090126719METHOD FOR PROCESSING SUGAR CANE FILTER CAKE MUD AND EXTRACTING COMPONENT PRODUCTS - A process for the treatment of sugar cane filter cake mud separates and extracts the mud's components into useful materials. The materials include fiber, lignin, beta-carotene, oil containing a high content of phytosterols, and refined wax. The fiber can be used as an animal feed or a source of energy, the refined wax is a resource of policosanol and other established purposes, and resin can be used an additive in asphalt mixtures and tire manufacturing or can be recycled back into the sugar milling process. The process is self contained, requiring the input only of fresh water and chemical additives to adjust pH and coloration.05-21-2009
20110124894METHOD FOR OBTAINING LONG CHAIN ALIPHATIC ALCOHOLS AND FATTY ACIDS FROM SUGAR CANE MUD AND RELATED WAX ESTERS - Methods are provided for the extraction of wax esters from sugar cane mud, isolation of the wax, saponification of the wax, either after isolation or in an intermediate un-isolated form to provide higher primary aliphatic alcohols (HPAA's) and fatty acids having nutritional and medicinal uses. The solid waste resulting from the process can be disposed of or utilized as a soil substitute following an optional water wash. Additionally, methods are provided for providing modified forms of the sugar cane mud or cachaza having reduced volumes and/or water content that require less storage space and capable of being stored for long periods of time with little or no biological degradation.05-26-2011

Patent applications by Rafael Almagro, Miami, FL US